Rationale, Design, and Experiences from the Vanguard Phase of the Bariatric Surgery for the Reduction of Cardiovascular Events (BRAVE) Trial [0.03%]
BAROCADE试验的rationale、设计及vanguard阶段经验
Jorge A Wong,David Conen,Aristithes Doumouras et al.
Jorge A Wong et al.
Background: Observational studies suggest that metabolic/bariatric surgery (MBS) reduces mortality and major adverse cardiovascular events in patients with obesity, but adequately powered randomized trials (RCTs) are lack...
Intensive Blood-Pressure Control for the Prevention of Major Cardiovascular Events in Patients with Type 2 Diabetes: Rationale, Design and Baseline Characteristics of the OPTIMAL-DIABETES Randomized Trial [0.03%]
糖尿病患者血压强化控制靶目标临床研究（OPTIMAL-DIABETES）设计与基线特征分析
Karla Santo,Eduardo Martins,Gisele S Silva et al.
Karla Santo et al.
Background: Evidence on the beneficial effects of intensive blood pressure (BP) control is still uncertain in patients with type 2 diabetes (T2D), particularly in an ethnically diverse population. ...
Rationale and Design of the TAILOR-HCM Multicenter Randomized Controlled Trial: Transapical Beating-Heart Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy [0.03%]
TAILO-HCM多中心随机对照试验的设计与立题依据：梗阻性肥厚型心肌病室间隔心内膜面切开术临床研究
Jing Fang,Yilei Ma,Yue Chen et al.
Jing Fang et al.
Background Septal myectomy is the gold standard treatment for drug-refractory obstructive hypertrophic cardiomyopathy (oHCM). However, conventional septal myectomy (CSM) has been largely confined to specialized centers owing to its technica...
Empagliflozin and Functional Capacity in Patients at Risk of Heart Failure [0.03%]
恩格列净与心力衰竭高风险患者的功能性容量之间的关系
Thomas H Marwick
Thomas H Marwick
Design, rationale, and baseline patient characteristics for the Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange (SCD-CARRE) trial [0.03%]
镰状细胞病和心血管风险-红细胞交换(SCD-CARRE)试验的设计、理由及基线患者特征
Marnie Bertolet,Darrell J Triulzi,Sally Campbell-Lee et al.
Marnie Bertolet et al.
Background: Despite wide utilization of automated red blood cell exchange (RBCX) transfusion in adult patients with sickle cell disease (SCD), no consensus or quality efficacy data exist on its use. The Sickle Cell Diseas...
Antegrade dissection and re-entry versus retrograde strategy in chronic total occlusion percutaneous coronary intervention: Rationale and design of the ADRENALINE randomized study [0.03%]
正向解剖再入路与逆向技术在慢性完全闭塞病变经皮冠状动脉介入治疗中效果的随机对照研究：ADRENALINE试验 rationale 和设计
Maksymilian P Opolski,Mateusz Spiewak,Filip Machaj et al.
Maksymilian P Opolski et al.
Rationale: While antegrade wiring (AW) is the most common initial strategy for chronic total occlusion (CTO) percutaneous coronary intervention (PCI), difficult CTO lesions frequently require either antegrade dissection a...
Integrative assessment of high-sensitivity C-reactive protein and lipid levels in predicting 20-year atherosclerotic cardiovascular disease risk, in a Mediterranean population: The ATTICA study (2002-2022) [0.03%]
高敏C反应蛋白和血脂水平在预测地中海人群20年动脉粥样硬化性心血管疾病风险方面的综合评估：ATTICA研究（2002-2022）
Sofia-Panagiota Giannakopoulou,Christina Chrysohoou,Smaragdi Antonopoulou et al.
Sofia-Panagiota Giannakopoulou et al.
Background: While inflammation is recognized as an independent risk factor for atherosclerotic cardiovascular disease (ASCVD), with high-sensitivity C-reactive protein (hs-CRP) serving as a prognostic indicator, the degre...
Interpreting apparent differences among the major colchicine trials for cardiovascular prevention: a descriptive compatibility analysis [0.03%]
解读科尔克辛心血管疾病预防主要试验结果表象差异：描述性兼容分析
Thomas C Scheier,Hertzel C Gerstein,Arend Mosterd et al.
Thomas C Scheier et al.
Background: Recent analyses and commentaries on the major colchicine trials have treated COLCOT and LoDoCo2 as defining the expected benefit of colchicine for cardiovascular prevention, with CLEAR SYNERGY viewed as the di...
Comparative effectiveness of torsemide vs furosemide in the management of heart failure patients: win-ratio reanalysis of the TRANSFORM-HF trial [0.03%]
托塞米与呋塞米治疗心力衰竭患者的疗效比较：TRANSFORM-HF试验的胜率重新分析结果
Guangyu Tong,Yukang Zeng,Stephen J Greene et al.
Guangyu Tong et al.
Background: Loop diuretics are widely used for managing congestion in patients with heart failure (HF). The TRANSFORM-HF trial is a multicenter randomized study that enrolled heart failure patients, comparing a strategy o...
Efficacy and safety of human albumin combined with furosemide in acute decompensated heart failure with hepatic dysfunction [0.03%]
人血白蛋白联合呋塞米治疗肝功能异常急性心衰患者的疗效及安全性研究
Georgios Chalikias,Dimitrios Stakos,Adina Thomaidis et al.
Georgios Chalikias et al.
Background: Congestion is the most common clinical presentation on admission of patients with acute decompensated heart failure (ADHF). Finding effective ways to alleviate congestion has become a pivotal management step. ...