Effects of Melatonin on the Expression of Invasion-Related Markers (MMP2 and MMP9) in Breast Cancer Cells [0.03%]
褪黑激素对乳腺癌细胞中侵袭相关标志物(MMP2和MMP9)表达的影响
Parvin Ghadimi,Saeid Ghorbian
Parvin Ghadimi
Breast cancer is one of the most common types of cancer in women, and metastasis is a leading cause of mortality in patients with this disease. This study investigated the effects of melatonin, a natural hormone, on the migration of cancer ...
Platelet-Derived Growth Factor Promotes Glomerular Mesangial Cells Differentiation of Human Bone Marrow Hematopoietic Stem Cells - An In Vitro Study [0.03%]
血小板源生长因子促进人骨髓造血干细胞体外分化为肾小球系膜细胞
Surekha Kattaru,Samundeshwari Echambadi Loganathan,Sireesha Kodavala et al.
Surekha Kattaru et al.
Glomerular filtration function and homeostasis are largely due to the cross-talk between podocytes, endothelial cells, and mesangial cells (MCs). Any disturbance in this association causes glomerular diseases (GD). Cell-based therapies are ...
Correction to "Overexpression of lncRNA WWTR1-AS1 Associates With Tumor Aggressiveness and Unfavorable Survival in Head-Neck Squamous Cell Carcinoma" [0.03%]
对“lncRNA WWTR1-AS1的过表达与头颈鳞癌的肿瘤侵袭性及不良预后相关”的更正
Published Erratum
Journal of cellular biochemistry. 2025 Mar;126(3):e70004. DOI:10.1002/jcb.70004 2025
Identification and Evaluation of IGF1R and Its Associated Proteins as Targets and Design of Novel Inhibitors for Cancer Therapy [0.03%]
IGF1R及其相关蛋白作为癌症治疗中靶点的识别与评估及新型抑制剂的设计
Tabrez Faruqui,Aubaidah Akhtar,Farheen Showket et al.
Tabrez Faruqui et al.
The insulin-like growth factor 1 receptor (IGF1R) is a crucial receptor tyrosine kinase involved in cellular growth, survival, and metabolism. Abnormal overexpression and activation are common in various cancers and contribute to tumor deve...
RETRACTION: MiR-101-3p Regulates the Viability of Lung Squamous Carcinoma Cells via Targeting EZH2 [0.03%]
撤消:MiR-101-3p通过靶向EZH2调节肺鳞状细胞癌的活力
Y. Hou, L. Li, Y. Ju, Y. Lu, L. Chang, and X. Xiang, "MiR-101-3p Regulates the Viability of Lung Squamous Carcinoma Cells via Targeting EZH2," Journal of Cellular Biochemistry 118, no. 10 (2017): 3142-3149, https://doi.org/10.1002/jcb.25836...
Exploring the Impact of LRRK2 WD40 G2294R Mutation on Conformation and Dimerisation Dynamics: Insights From Molecular Dynamics Simulation [0.03%]
LRRK2 WD40 G2294R突变对构象和二聚体化动力学影响的分子动力学模拟研究
Chuancheng Wei,Choon Han Heh,Sek Peng Chin
Chuancheng Wei
LRRK2 has gained prominence in treating Parkinson's disease as a potential drug target. Mutations in the WD40 domain, like G2294R, are notable for their influence on the stability and dimerisation of the LRRK2. Studies have shown that G2294...
Decoding SARS-CoV-2 Inhibition: Insights From Molecular Dynamics Simulation of Condensed Amino Thiourea Scaffold Small Molecules [0.03%]
解码对SARS-CoV-2的抑制作用:来自浓缩氨基酸硫脲骨架小分子分子动力学模拟的见解
Xiaoli Shen,Hao Zhang,Pengyin Zhang et al.
Xiaoli Shen et al.
The main protease (Mpro) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) plays a crucial role in viral replication. In this study, the binding modes and inhibitory mechanisms of eight condensed amino thiourea scaffold inhibi...
Peroxisome Proliferator-Activated Receptor-Gamma Activation by an Active Compound in Lythrum anceps (Koehne) Makino [0.03%]
Lythrum anceps (Koehne) Makino中的一种活性化合物通过激活过氧化物酶体增殖物激活受体-gamma发挥活性
Ryo Miyata,Masanobu Suzuki,Yuka Okazaki et al.
Ryo Miyata et al.
Lythrum anceps (Koehne) Makino (Japanese common name: "Misohagi") is an edible plant belonging to the Lythraceae family. It is mainly distributed in Asia, Northern Africa, and Europe. Plants of the genus Lythrum exhibit a broad range of bio...
Transforming Growth Factor-β Modulates Cancer Stem Cell Traits on CD44 Subpopulations in Hepatocellular Carcinoma [0.03%]
转化生长因子-β通过CD44亚群调节肝癌干细胞样特征
Mario Alejandro Aguilar-Chaparro,Sonia Andrea Rivera-Pineda,Hury Viridiana Hernández-Galdámez et al.
Mario Alejandro Aguilar-Chaparro et al.
Hepatocellular carcinoma (HCC) is a formidable malignancy, with growing interest in identifying cancer stem cells (CSCs) as potential therapeutic targets. CD44 isoforms have emerged as promising CSC markers in HCC, often associated with epi...
Hypoxic Secretome and Exosomes Derived From Human Glioblastoma Cells (U87MG) Promote Protumorigenic Phenotype of Microglia in Vitro [0.03%]
人胶质母细胞瘤细胞(U87MG)的缺氧分泌组和外泌体可促进小胶质细胞的促肿瘤发生表型
Sangati Pancholi,Ritvi Shah,Utsav Bose et al.
Sangati Pancholi et al.
Glioblastoma multiforme (GBM), a highly heterogeneous CNS tumor known for its highest incidence rates and poor prognosis has shown limited success in the therapies due to hypoxia-driving immune-suppression in the tumor microenvironment (TME...