Alice L Mueller,Sabra L Klein
Alice L Mueller
The prevalence and severity of cancers in non-reproductive tissues are greater in males than females, but the sex-specific factors contributing to this remain ill described. In this issue of Immunity, Yang et al. (2022) uncover a mechanism ...
Leah S Hohman,Lisa C Osborne
Leah S Hohman
A plethora of studies have established the importance of eosinophils in protective immunity against infections and in allergy. In this issue of Immunity, Ignacio et al. (2022) define a vital for eosinophils in coordinating a microbiota-epit...
Ankit Malik,Bana Jabri
Ankit Malik
Intra-epithelial T cells make up a significant proportion of immune cells in the body, yet their development and function remain an enigma. In this issue of Immunity, Parsa et al. (2022) describe the differentiation and cross-protective fun...
CD4+ progenitor cells sustain helper responses during chronic infection [0.03%]
CD4+前体细胞在慢性感染期间维系辅助性反应
Laura M Snell
Laura M Snell
How CD4+ T cell responses are maintained during chronic infection is unknown. In this issue of Immunity, Xia et al. (2022) identify a progenitor T cell subset that gives rise to effector and follicular helper T cells to sustain antiviral re...
Response to contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells [0.03%]
小鼠 kupffer 细胞与肝窦内皮细胞分离培养的污染及应对措施
Matteo Iannacone,Camille Blériot,Francesco Andreata et al.
Matteo Iannacone et al.
Contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells [0.03%]
小鼠 kupffer 细胞与肝窦内皮细胞的交叉污染
David A Hume,Stefan Offermanns,Remy Bonnavion
David A Hume
Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients [0.03%]
基于高通量质谱流式技术的COVID-19住院患者免疫重建规律研究
Cassandra E Burnett,Trine Line Hauge Okholm,Iliana Tenvooren et al.
Cassandra E Burnett et al.
While studies have elucidated many pathophysiological elements of COVID-19, little is known about immunological changes during COVID-19 resolution. We analyzed immune cells and phosphorylated signaling states at single-cell resolution from ...
Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3 [0.03%]
人类中和抗体图谱及奥密克戎亚变体BA.1/BA.1.1/BA.2/BA.3的逃逸性
Min Huang,Lili Wu,Anqi Zheng et al.
Min Huang et al.
SARS-CoV-2 Omicron variant has presented significant challenges to current antibodies and vaccines. Herein, we systematically compared the efficacy of 50 human monoclonal antibodies (mAbs), covering the seven identified epitope classes of t...
Tom Aschman,Ronja Mothes,Frank L Heppner et al.
Tom Aschman et al.
Neurological symptoms in SARS-CoV-2-infected patients have been reported, but their cause remains unclear. In theory, the neurological symptoms observed after SARS-CoV-2 infection could be (1) directly caused by the virus infecting brain ce...
Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism [0.03%]
病毒感染通过容许机制产生真正和旁观者两类驻肺记忆B细胞亚群
Claude Gregoire,Lionel Spinelli,Sergio Villazala-Merino et al.
Claude Gregoire et al.
Lung-resident memory B cells (MBCs) provide localized protection against reinfection in respiratory airways. Currently, the biology of these cells remains largely unexplored. Here, we combined influenza and SARS-CoV-2 infection with fluores...