ESI-MS/MS Characterisation of Phenolic Reaction Products of Nitrogen Mustards and N,N-Dialkylaminoethyl-2-Chlorides and Their Rapid Screening by LC-MS/MS in Neutral Loss Scan Mode [0.03%]
氮芥和N，N-二烷基氨基乙基-2-氯化物反应产物的酚类反应产的ESI-MS/MS表征及其LC-MS/MS中通过中性丢失扫描模式快速筛选
M Nikita Singh,K G Harsha,V V S Lakshmi et al.
M Nikita Singh et al.
Rationale: Nitrogen mustards (HN1, HN2 and HN3) and N,N-dialkylaminoethyl-2-chlorides (where alkyl = methyl, ethyl, isopropyl, or propyl) contain reactive chloride bonds that react with phenol in environmental samples to ...
Advanced Phosphoproteomics Depth and Quantitative Performance Using an Integrated noFAIMS-FAIMS Approach [0.03%]
利用集成式无偏FAIMS-FAIMS技术提高磷酸化蛋白质组学的深度和定量性能
Byoung-Kyu Cho,Antonia Zamacona Calderon,Young Ah Goo
Byoung-Kyu Cho
Rationale: Protein phosphorylation plays a central role in regulating cellular signaling, and its dysregulation is closely linked to diseases such as cancer and neurodegeneration. Mass spectrometry-based phosphoproteomics...
Efficient and Simultaneous LC-MS/MS Detection of N-Nitroso and Di-Nitroso Leucovorin in Leucovorin Drug Products: Method Development and Validation [0.03%]
亚叶酸药品中N-亚硝基和Di- nitroso亚叶酸的高效同时LC-MS/MS检测：方法开发与验证
Jaya Yalamanchili,Himavathi Ganja,Suresh Salakolusu
Jaya Yalamanchili
Rationale: The occurrence of complex nitrosamines, namely, N-nitroso drug substance related impurities (NDRSI) in pharmaceuticals is of great concern due to their potential carcinogenic and mutagenic properties. This crea...
Characterization of Amidine-Based Degradation Products of Novichok A-Series Nerve Agents Using Single-Quadrupole GC-MS [0.03%]
基于酰胺
Priyanka Yadav,M V Jagadish,Prachi Thukral et al.
Priyanka Yadav et al.
Rationale: The identification of Novichok A-series nerve agents depends primarily on the detection of stable degradation products, as intact agents are rarely encountered in environmental or forensic samples. However, lim...
δ13C and δ15N Values of Residues Provide Insights Into Identification of the Explosive Source [0.03%]
残留物的碳氮同位素组成揭示爆炸物来源的新途径
James R Ehleringer,John D Howa
James R Ehleringer
Rationale: Postblast analyses of military and terrorist events will benefit from the capacity to learn more about the explosive materials used in an event. Here stable isotope ratio analyses (δ13C, δ15N) can provide add...
Correction to 'Analysing Sr Isotopes in Low-Sr Samples Such as Single Insects With Inductively Coupled Plasma Tandem Mass Spectrometry Using N2O as a Reaction Gas for In-Line Rb Separation' [0.03%]
关于“用N2O作为反应气体联线分离Rb进行ICP-MS/MS法分析昆虫等低Sr样品”的更正
Published Erratum
Rapid communications in mass spectrometry : RCM. 2026;40(10):e70059. DOI:10.1002/rcm.70059 2026
UHPLC-MS/MS Quantification of Human Cytosolic Aldehyde Oxidase: Heat-Assisted In-Solution Protein Denaturation and Digestion [0.03%]
高效液相色谱-串联质谱法定量人细胞质甲醛氧化酶：热辅助溶液中蛋白质变性和消化方法
Shiyan Chen,Aik Jiang Lau
Shiyan Chen
Rationale: The quality of protein denaturation and digestion is critical in determining the performance of a UHPLC-MS/MS method in absolute protein quantification. Previous UHPLC-MS/MS methods on human aldehyde oxidase (A...
Sensitive Detection of Salmonella Susceptibility to Ceftriaxone and Azithromycin Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry [0.03%]
基质辅助激光解析电离飞行时间质量测定法检测沙门氏菌对头孢曲松和阿奇霉素的敏感性
Guohao Zhan,Shujin Xie,Jinyu Zhang et al.
Guohao Zhan et al.
Background: The rising incidence of Salmonella-induced diarrhea highlights the critical need for judicious antibiotic use to ensure effective treatment outcomes. ...
Michael J Mohr,Linus Strähle,Tobias Bader et al.
Michael J Mohr et al.
Rationale: The quality of analytical measurements is typically evaluated after completion of the entire, or possibly multiple, measurement batch(es). Automated, near real-time quality control (QC) during LC-HRMS acquisiti...
Rapid Detection of Plasticizer Migration From UV-Aged PVC Films by DART-HRMS [0.03%]
基于DART-HRMS的PVC薄膜紫外老化后塑化剂快速迁移检测方法研究
Odilon Leite-Barbosa,Marcelo Ferreira Leão de Oliveira,Márcia Gomes de Oliveira et al.
Odilon Leite-Barbosa et al.
Rationale: The migration of phthalate plasticizers from high-volume polymers, such as poly(vinyl chloride) (PVC), raises significant toxicological concerns, particularly when materials are subjected to aging and environme...