Phase III randomized trial comparing palliative systemic therapy to best supportive care in advanced esophageal/GEJ cancer [0.03%]
一项比较晚期食管/胃食管结合部癌姑息性全身治疗与最优支持护理的III期随机试验
Vanita Noronha,Vijay Maruti Patil,Nandini Menon et al.
Vanita Noronha et al.
No study has unequivocally proven that chemotherapy prolongs overall survival (OS) in advanced esophageal cancer. We conducted a Phase III randomized study in first-line advanced unresectable/metastatic esophageal/GEJ cancer. Patients aged ...
Evolution of genome and immunogenome in esophageal squamous cell carcinomas driven by neoadjuvant chemoradiotherapy [0.03%]
新辅助化学免疫治疗驱动的食管鳞癌基因组和免疫组氨酸的演变规律研究
Zelin Weng,Zihang Mai,Jianye Yuan et al.
Zelin Weng et al.
Neoadjuvant chemoradiotherapy (NCRT) followed by surgery is a standard treatment for locally advanced esophageal squamous cell carcinomas (ESCCs). However, the evolution of genome and immunogenome in ESCCs driven by NCRT remains incompletel...
Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy [0.03%]
放射治疗后三阴性乳腺癌细胞中半乳糖凝集素-9表达增强:靶向治疗的启示
Cédric Lerévérend,Nour Kotaich,Lucille Cartier et al.
Cédric Lerévérend et al.
Optimizations are expected in the development of immunotherapy for the treatment of Triple-negative breast cancer (TNBC). We studied the expression of galectin-9 (Gal-9) after irradiation and assessed the differential impacts of its targeti...
Pre-diagnostic plasma advanced glycation end-products and soluble receptor for advanced glycation end-products and mortality in colorectal cancer patients [0.03%]
结直肠癌患者术前血清晚期糖基化终产物和晚期糖基化终末产物受体在癌症特异性和全因死亡率中的作用研究
Jinze Li,Jacqueline Roshelli Baker,Elom K Aglago et al.
Jinze Li et al.
Advanced glycation end-products (AGEs), formed endogenously or obtained exogenously from diet, may contribute to chronic inflammation, intracellular signaling alterations, and pathogenesis of several chronic diseases including colorectal ca...
Fred Bunz
Fred Bunz
Association of opium use and tobacco smoking with α-, β-, and γ-human papillomavirus oral infection [0.03%]
鸦片使用和烟草吸烟与口腔α、β和γ人乳头瘤病毒感染的关系
Abbas Karimi,Elham Mohebbi,Sandrine Mckay-Chopin et al.
Abbas Karimi et al.
Head and neck squamous cell carcinomas (HNSCCs) are linked to tobacco smoking, opium use, and human papillomavirus (HPV) infection. However, little is known about the association of HPV infection with risk factors of HNSCCs, including opium...
Multicenter Study
International journal of cancer. 2024 Nov 1;155(9):1544-1548. DOI:10.1002/ijc.35086 2024