Intestinal mucositis, systemic inflammation and bloodstream infections following high-dose methotrexate treatment in childhood acute lymphoblastic leukaemia: Comparison between the NOPHO ALL 2008 protocol and the ALLTogether1 protocol [0.03%]
高剂量化疗治疗儿童急性淋巴细胞白血病后肠道黏膜炎、全身性炎症和血液感染：NOPHO ALL 2008方案与ALLTogether1方案的比较
Sarah Weischendorff,Silvia de Pietri,Mathias Rathe et al.
Sarah Weischendorff et al.
Severe intestinal mucositis (IM) increases the risk of bloodstream infections (BSI) and inflammatory toxicity during acute lymphoblastic leukaemia (ALL) induction treatment. However, the implications of IM in subsequent ALL therapy phases a...
Comparative Study
International journal of cancer. 2025 Jan 1;156(1):164-173. DOI:10.1002/ijc.35136 2025
Identification of epigenetic modifiers essential for growth and survival of AML1/ETO-positive leukemia [0.03%]
鉴定对AML1/ETO阳性白血病生长和生存必不可少的表观遗传修饰因子
Jesús Duque-Afonso,Pia Veratti,Usama-Ur Rehman et al.
Jesús Duque-Afonso et al.
Aberrant gene expression patterns in acute myeloid leukemia (AML) with balanced chromosomal translocations are often associated with dysregulation of epigenetic modifiers. The AML1/ETO (RUNX1/MTG8) fusion protein, caused by the translocatio...
Clinical and molecular features of early onset pancreatic adenocarcinoma [0.03%]
早发性胰腺导管腺癌的临床和分子特征分析
Maxime Rémond,Cristina Smolenschi,Anthony Tarabay et al.
Maxime Rémond et al.
Pancreatic adenocarcinoma (PDAC) is a major health burden and may become the second cause of death by cancer in developed countries. The incidence of early-onset pancreatic cancer (EOPC, defined by an age at diagnosis 50). Eight hundred and...
Laila Sara Arroyo Mühr,Jiangrong Wang,Sadaf S Hassan et al.
Laila Sara Arroyo Mühr et al.
In well-screened populations, most cervical cancers arise from small groups of women with inadequate screening. The present study aims to assess whether registry-based cancer risk assessment could be used to increase screening intensity amo...
Stemness and hybrid epithelial-mesenchymal profiles guide peritoneal dissemination of malignant mesothelioma and pseudomyxoma peritonei [0.03%]
间充质和混合上皮-间质细胞特征引导恶性间皮瘤和腹膜假黏液瘤的腹膜转移
Nayana Lazzari,Giulia Rigotto,Barbara Montini et al.
Nayana Lazzari et al.
Intrabdominal dissemination of malignant mesothelioma (MM) and pseudomyxoma peritonei (PMP) is poorly characterized with respect to the stemness window which malignant cells activate during their reshaping on the epithelial-mesenchymal (E/M...
A multicenter, prospective, phase II trial of second-line aflibercept plus FOLFIRI in patients with metastatic colorectal cancer refractory to an anti-EGFR antibody: HGCSG1801 [0.03%]
抗EGFR抗体耐药的转移性结直肠癌二线使用阿柏西普联合FOLFIRI的多中心前瞻性Ⅱ期临床研究：HGCSG1801
Hiroshi Nakatsumi,Yoshito Komatsu,Kazuaki Harada et al.
Hiroshi Nakatsumi et al.
Aflibercept (AFL) plus FOLFIRI prolongs overall survival (OS) in patients with metastatic colorectal cancer (mCRC). However, there is limited evidence on the efficacy and safety of AFL plus FOLFIRI previously treated with anti-epidermal gro...
Reply to: Comments on "Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta-analysis" [0.03%]
关于“心理社会因素、健康行为与癌症发病率：在个体患者数据meta分析中测试交互作用和效应修饰”的评论回复
Maartje Basten,Lonneke A van Tuijl,Kuan-Yu Pan et al.
Maartje Basten et al.
The implications of the TNFα-TNFR2 immune checkpoint signaling pathway in cancer treatment: From immunoregulation to angiogenesis [0.03%]
肿瘤治疗中TNFα-TNFR2免疫检查点信号通路的含义：从免疫调节到促血管生成
Melissa Emamalipour,Sara Shamdani,Behzad Mansoori et al.
Melissa Emamalipour et al.
Despite the tremendous advances that have been made in biomedical research, cancer remains one of the leading causes of death worldwide. Several therapeutic approaches have been suggested and applied to treat cancer with impressive results....
Self-collected versus clinician-collected anal swabs for anal cancer screening: A systematic review and meta-analysis [0.03%]
自采与临床医生采集肛管拭子用于肛管癌筛查：系统评价和 meta 分析
Clare E F Dyer,Fengyi Jin,Richard J Hillman et al.
Clare E F Dyer et al.
Anal squamous cell carcinoma (ASCC) incidence is increasing globally. International consensus guidelines published in 2024 include HPV and/or cytology testing of anal swabs in those at greatest risk of ASCC. Self-collected anal swabs may be...