Aflatoxin exposure is associated with an increased risk of gallbladder cancer [0.03%]
黄曲霉毒素的暴露与胆囊癌的发病风险增加有关
Amit Yadav,Pankaj Gupta,Parikshaa Gupta et al.
Amit Yadav et al.
Gall bladder cancer (GBC) is common among the socioeconomically deprived populations of certain geographical regions. Aflatoxin is a genotoxic hepatocarcinogen, which is recognized to have a role in the pathogenesis of hepatocellular carcin...
Response to: Comments on "Epidemiological trends and survival of oropharyngeal cancer in a high HPV-prevalent area: A Danish population-based study from 2000 to 2020" [0.03%]
对“丹麦2000-2020年人乳头瘤病毒高流行区的口腔癌流行趋势及生存研究”一文的回复
Christian von Buchwald,Benedicte Bitsch Lauritzen,Amanda-Louise Fenger Carlander et al.
Christian von Buchwald et al.
14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer [0.03%]
14-3-3σ通过将YY1限制在细胞质中促进结直肠癌的治疗抵抗及肿瘤进展
Amol Lonare,Kumarkrishna Raychaudhuri,Sanket Shah et al.
Amol Lonare et al.
14-3-3σ functions as an oncogene in colorectal cancer and is associated with therapy resistance. However, the mechanisms underlying these observations are not clear. The results in this report demonstrate that loss of 14-3-3σ in colorecta...
Combined inhibition of RAD51 and CHK1 causes synergistic toxicity in cisplatin resistant cancer cells by triggering replication fork collapse [0.03%]
RAD51和CHK1的联合抑制通过触发复制叉崩溃在顺铂耐药癌细胞中引起协同毒性反应
Julia Mann,Kathrin Niedermayer,Johannes Krautstrunk et al.
Julia Mann et al.
The therapeutic efficacy of the anticancer drug cisplatin is limited by acquired drug resistance. Cisplatin forms DNA crosslinks, that, if not removed, lead to replication stress. Due to this, the DNA damage response (DDR) gets activated re...
Tumor deposits should not be placed in the M category of TNM: A comparative survival analysis using SEER data [0.03%]
肿瘤沉积不应放在TNM的M分类中：使用SEER数据进行的比较生存分析
Ayse Selcen Oguz Erdogan,Femke Simmer,Iris D Nagtegaal
Ayse Selcen Oguz Erdogan
Tumor deposits (TD) are tumor nodules in the lymphatic drainage area of colorectal cancer patients, and they are currently classified in the N category in the TNM classification. However, due to the associated poor prognosis, some small coh...
Comparative Study
International journal of cancer. 2025 Jan 15;156(2):274-279. DOI:10.1002/ijc.35165 2025
The Man Van: A pilot study of using mobile targeted case-finding to address health inequalities in prostate cancer [0.03%]
针对前列腺癌采用流动诊所开展目标病例搜索以解决健康不平等的试点研究
Masood Moghul,Amina Tran,Fionnuala Croft et al.
Masood Moghul et al.
Early diagnosis remains a major limitation of cancer outcomes with ethnicity and deprivation being determinants of inequalities that impact outcomes. Prostate cancer suffers from lower incidence rates and higher mortality rates in the most ...
Impact of accelerated biological aging and genetic variation on esophageal adenocarcinoma: Joint and interaction effect in a prospective cohort [0.03%]
加速衰老与遗传变异相互作用增加食管腺癌发病风险：一项前瞻性队列研究证据
Renjia Zhao,Huangbo Yuan,Shuaizhou Chen et al.
Renjia Zhao et al.
Accelerated biological aging may be associated with increased risk of esophageal adenocarcinoma (EAC). However, its relationship with genetic variation, and its effect on improving risk population stratification, remains unknown. We perform...
Use of menopausal hormone therapy before and after diagnosis and ovarian cancer survival-A prospective cohort study in Australia [0.03%]
绝经激素治疗与卵巢癌生存的关系：澳大利亚前瞻性队列研究
Renhua Na,Susan J Jordan,Anna DeFazio et al.
Renhua Na et al.
Menopausal hormone therapy (MHT) use before ovarian cancer diagnosis has been associated with improved survival but whether the association varies by type and duration of use is inconclusive; data on MHT use after treatment, particularly th...
Fredrik Mertens,Jakob Hofvander,Nils Mandahl et al.
Fredrik Mertens et al.
Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typica...