Integrating Shared Decision-Making Into Breast Cancer Postmastectomy Reconstruction: A Systematic Review of Evidence, Barriers, and Real-World Implementation [0.03%]
乳房癌术后重建中共同决策的应用：证据、障碍及实施的系统性回顾
Marta Maes-Carballo,Natalia de-la-Puente-Mota,Laura Sampol-Ramírez et al.
Marta Maes-Carballo et al.
This systematic review synthesizes empirical evidence on the development, effectiveness, patient experience, and implementation of decision aids (DAs) for postmastectomy breast reconstruction (PMBR) and to evaluate the role of pre-consultat...
Penpulimab and Gemcitabine With or Without Anlotinib in Metastatic Nasopharyngeal Carcinoma: A Randomized, Open-Label, Multicenter Phase 2 Study [0.03%]
派安普利单抗联合吉西他滨与或不联合阿尼鲁单抗用于转移性鼻咽癌：一项随机、开放标签、多中心Ⅱ期研究
Shuang Huang,Ya-Qian Han,Kun-Yu Yang et al.
Shuang Huang et al.
This prospective exploratory phase 2 study employed a three-cohort, two-phase design to evaluate the potential of anlotinib as a substitute for cisplatin in gemcitabine-penpulimab combinations for metastatic nasopharyngeal carcinoma (NPC) p...
Can Response Outcomes Predict Survival in Paediatric Patients Receiving Treatment for Relapsed and Refractory Rhabdomyosarcoma? Results From the Living-REFoRMS Systematic Review [0.03%]
儿童复发和难治性横纹肌肉瘤患者接受治疗后的缓解情况能否预测生存期？Living-REFoRMS系统评价的结果
Preethi Muthukumar,Lucy Shepherd,Sumayya Anwer et al.
Preethi Muthukumar et al.
The relationship between radiological response and survival outcomes has been studied in upfront treatment in paediatric rhabdomyosarcoma and adult cancer settings. However, the extent of the relationship between these outcomes is unknown i...
Population-Based First Estimates of the Effect of HPV Vaccination in Three Italian Areas Covered by Organised Cervical Screening [0.03%]
基于人口的宫颈癌筛查项目中接种HPV疫苗的效果评估初步估计-以意大利3个地区为例
Paola Armaroli,Marco Zappa,Paolo Giorgi Rossi et al.
Paola Armaroli et al.
In Italy, the first women invited for HPV vaccination at 15-16 years reached the age for cervical screening (25 years) in 2018. The real-world vaccination impact was evaluated. Women born in 1993-1996 invited for organised cervical screenin...
Late and Durable Minimal Residual Disease Response Predicts Favorable Outcomes in Newly Diagnosed Multiple Myeloma [0.03%]
新诊断的多发性骨髓瘤患者晚期且持久的微小残留病灶缓解预示着良好的结局
Jieqiong Zhou,Wenqiang Yan,Yuntong Liu et al.
Jieqiong Zhou et al.
Minimal residual disease (MRD) negativity is a well-established prognostic marker in multiple myeloma (MM), yet the clinical relevance of MRD response timing and duration remains unclear, particularly in real-world settings. We retrospectiv...
Targeting ERα Coregulator Networks to Overcome Endocrine Resistance in ER+ Breast Cancer [0.03%]
靶向ERα共调节网络以克服阳性乳腺癌中的内分泌耐药性
Monika Bar,Wiesława Widłak,Natalia Vydra
Monika Bar
Breast cancer (BC) is the most commonly diagnosed tumor among women worldwide. Approximately 70% of cases are estrogen receptor-positive (ER+), whose growth is driven by estrogen signaling. Endocrine therapies targeting ER signaling are the...
Skeletal Muscle Metastasis in Patients With SMARCA4-Deficient Thoracic Tumors: A Retrospective Cohort Study [0.03%]
SMARCA4缺陷型胸部肿瘤患者中骨骼肌转移的回顾性队列研究
Xueyuan Chen,Mengting Shi,Yuwen Yang et al.
Xueyuan Chen et al.
SMARCA4-deficient thoracic tumor (SDTT) is a malignant tumor with a poor prognosis that often presents with distant metastases at the time of clinical diagnosis. Skeletal muscle metastasis is a rare subtype of metastasis patterns, and there...
Associations of Outdoor Air Pollution With Incidence of Cancers Other Than Lung Cancer in a Large US Prospective Cohort [0.03%]
美国一大型前瞻性队列中室外空气污染与除肺癌外的癌症发病率的关系
W Ryan Diver,Lauren R Teras,Emily L Deubler et al.
W Ryan Diver et al.
Outdoor air pollution, including particulate matter (PM), is a Group 1 carcinogen based on evidence for lung cancer; however, evidence for other cancers is limited. Further research on cancer incidence rather than mortality endpoints is nee...
Higher Daytime Light Exposure Predicts Lower Risk of Gastrointestinal Cancer Incidence and Mortality [0.03%]
较高的白天光暴露预测较低的消化系统癌症发病率和死亡率
Xionge Mei,Wei Wang,Nana Zheng et al.
Xionge Mei et al.
Daytime light exposure is essential for health, primarily by synchronizing tissue and cellular-level clocks with the external light/dark cycle. Insufficient exposure may disrupt circadian alignment and contribute to adverse outcomes, includ...
Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer [0.03%]
仑伐替尼与抗生素联合使用提高分化型甲状腺癌敏感性的潜在机制研究
Celina Ablinger,Petra Huber-Cantonati,Daniela D Weber et al.
Celina Ablinger et al.
Approved in 2015 for radioiodine-refractory differentiated thyroid carcinoma (RR-DTC), the multikinase inhibitor lenvatinib has demonstrated substantial efficacy; nevertheless, severe adverse effects, intrinsic resistance or development of ...