Optical Genome Mapping Reveals Frequent Cryptic Structural Aberrations in Normal Karyotype Acute Myeloid Leukemia [0.03%]
光学基因组测绘揭示正常染色体急性髓系白血病中频繁出现的隐蔽性结构异常
Tuuni Turtinen,Andriana Valkama,Christopher Wray et al.
Tuuni Turtinen et al.
Approximately half of newly diagnosed acute myeloid leukemia (AML) cases are cytogenetically normal (CN) when analyzed with conventional karyotyping. However, CN-AML exhibits a wide range of clinical heterogeneity, which may partly be expla...
Cardiovascular disease incidence and cancer risk in two large European prospective cohorts [0.03%]
欧洲两大前瞻性队列研究中的心血管病发病率与癌症风险关系研究
Emma Fontvieille,Vivian Viallon,Laia Peruchet-Noray et al.
Emma Fontvieille et al.
Our study investigated the association between incident cardiovascular disease (CVD) and subsequent cancer risk in two large European prospective cohorts. We included 568,926 adults from the European Prospective Investigation into Cancer an...
Nimotuzumab Combined With Concurrent Curative Radiotherapy and S-1 in 75 Years and Older Patients With Stage II-IVB Esophageal Squamous Cell Carcinoma: A Phase II Study [0.03%]
尼莫单抗联合同步放疗和S-1治疗≥75岁II-IVB期食管鳞癌患者的Ⅱ期临床研究
Xiaojie Xia,Jingze Yan,Lu Xu et al.
Xiaojie Xia et al.
Concurrent chemoradiotherapy is the standard treatment for inoperable, locally advanced esophageal cancer. However, older patients often have reduced tolerance to radiotherapy and concurrent intravenous chemotherapy due to declining physica...
Cancer Risk in Marfan Syndrome: A Swedish Population-Based Cohort Study [0.03%]
马方综合征的癌症风险：一项瑞典人群队列研究
Ida Nordgren,Anna Skarin Nordenvall,Alexandra Wachtmeister et al.
Ida Nordgren et al.
Marfan syndrome is an autosomal dominant connective tissue disorder caused by pathogenic variants in the fibrillin-1-encoding gene. The cancer risk in Marfan syndrome is not fully understood, but recent reports have suggested an increased r...
Diurnal Patterns of Accelerometer-Measured Physical Activity and Sleep in Relation to Cancer Risk: Findings From a Nationally Representative Study [0.03%]
来自全国性研究的发现：加速计测量的日间身体活动和睡眠模式与癌症风险的关系
Bowen Chen,Yue Wu,Yining Li et al.
Bowen Chen et al.
Physical activity (PA) and sleep are modifiable lifestyle factors, yet their circadian patterns in relation to cancer risk remain unclear. This study investigated their independent and joint associations with cancer risk. We analyzed data f...
Chemoimmunotherapy With or Without Thoracic Radiotherapy for Elderly Patients in Advanced Non-Small Cell Lung Cancer [0.03%]
老年晚期非小细胞肺癌化疗免疫治疗联合或不联合胸部放疗的研究
Zhiru Gao,Linlin Yang,Linlin Wang
Zhiru Gao
The optimal integration of thoracic radiotherapy (TRT) with first-line chemoimmunotherapy for elderly patients with driver-negative advanced non-small cell lung cancer (NSCLC) remains undefined. We conducted a real-world study to assess the...
Comments on "Trends and Epidemiology of Human Papillomavirus-Related Oropharyngeal Cancer in Chinese Populations From 2010 to 2024" [0.03%]
关于“中国人群2010至2024年人类乳头瘤病毒相关口咽癌流行趋势”的评论
Hongshuai Liu,Taotao Zhang,Linrong Wu et al.
Hongshuai Liu et al.
Risk-Benefit of Phase 2 Monotherapy Trials in Adult Solid Cancers: A Systematic Review and Meta-Analysis [0.03%]
成人实体瘤二期单药试验的风险与效益：系统性回顾和meta分析
Charlotte Ouimet,Monica Rosu,Jonathan Kimmelman
Charlotte Ouimet
Phase 2 (and phase 1 dose expansion, which we label phase 2 for the purposes of this study) cancer trials are the first direct tests of a new drug's efficacy. Because efficacy evidence is lacking, the therapeutic status of drug administrati...
ICLAC Register Version 14: A Continuing Legacy of the International Journal of Cancer [0.03%]
ICLAC注册第14版：《国际癌症杂志》的延续遗产
Ralf Weiskirchen
Ralf Weiskirchen
The Relevance of Curative-Intent Metastasectomy in Colorectal Cancer Patients: Real-World Insights From a Certified Comprehensive Cancer Center in Germany [0.03%]
德国认证综合癌症中心直肠癌患者的治愈性转移灶手术的现实世界见解
Julian W Holch,Jo-Ann Eisenburger,Antony Weber et al.
Julian W Holch et al.
Long-term survival in metastatic colorectal cancer (mCRC) can be achieved by curative-intent metastasectomy. Patients ineligible for upfront (primary) metastasectomy (PM) may become candidates for secondary metastasectomy (SM) following res...