Comments on 'Survival by Detection Pathway in Patients With Lung Cancer: A Nationwide Descriptive Epidemiological Study in Japan' [0.03%]
关于“日本肺癌患者通过检测途径幸存的全国描述性流行病学研究”的评论
Masashi Matsuzaka,Rina Tanaka
Masashi Matsuzaka
Incidence Trends of Colorectal Cancer by Social and Behavioral Factors-A Pooled Cohort Study [0.03%]
基于社会和行为因素的结直肠癌发病趋势-一项队列研究
Emilia Muhonen,Karri Seppä,Heidi Ryynänen et al.
Emilia Muhonen et al.
Colorectal cancer (CRC) represents more than 10% of the global cancer burden. Unlike in some other cancers, no single risk factor accounts for most CRC cases. Despite the well-studied overall incidence trend of CRC, little information is av...
Aumolertinib Versus Osimertinib as First-Line Treatment for EGFR-Mutant Non-Small Cell Lung Cancer: A Retrospective Real-World Multicenter Study [0.03%]
艾伏敏与奥希替尼一线治疗EGFR突变型非小细胞肺癌的回顾性真实世界多中心研究
Jinxia Wang,Ping Qi,Jinhua Li et al.
Jinxia Wang et al.
While third-generation EGFR tyrosine kinase inhibitors (TKIs) improve outcomes in EGFR-mutant NSCLC, optimal selection between these agents remains uncertain. This real-world study compares the efficacy and safety of aumolertinib with those...
Reply to: Comments on "Survival by Detection Pathway in Patients With Lung Cancer-A Nationwide Descriptive Epidemiological Study in Japan" [0.03%]
关于“日本全国范围内的肺癌患者生存检测路径描述性流行病学研究”的评论回复
Ryo Koto,Atsuki Yamamoto,Ikumi Takashima et al.
Ryo Koto et al.
Changing the History of Science-An Editorial Perspective on Critical Developments in Current Citation Practice, "Forgetting" the Pioneers of Scientific Discoveries [0.03%]
改写科学史——对当前引用实践中的批判性发展的一种编辑视角以及“遗忘”科学发现的先驱者
Heike Allgayer,Petra Boukamp
Heike Allgayer
Future Trends in Cancer Prevention and Interception in Cancer Predisposition Syndromes: Leveraging Insights From High-Risk Populations [0.03%]
癌症易感综合征中癌症预防和阻断的未来趋势：利用高危人群的见解
Yiming Wang,David Malkin,Steven M Lipkin
Yiming Wang
Cancer predisposition syndromes (CPS), arising from germline pathogenic variants in cancer predisposition genes (CPGs), are increasingly recognized as major contributors to pediatric and adult malignancies. Recent genomic advances have sign...
Sodium-Glucose Cotransporter 2 Inhibitors and Cancer Risk in Patients With Type 2 Diabetes Mellitus: An Active Comparator, New-User Cohort Study [0.03%]
2型糖尿病 mellitus患者使用钠-葡萄糖共转运蛋白2抑制剂与癌症风险：一组活性对照、新用户队列研究
Yuhao Li,Huatang Zeng,Fang Du et al.
Yuhao Li et al.
The association between sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and cancer risk in type 2 diabetes mellitus (T2DM) patients remains controversial. This study aimed to investigate whether SGLT-2i use is associated with a reduced ...
Deficient Mismatch Repair Represents a Distinct Molecular Feature of Early-Onset Colorectal Cancer in Chinese Single-Center Cohort [0.03%]
中国单中心结直肠癌队列中错配修复缺陷是早期结直肠癌的一个独特分子特征
Deng Tang,Zhigang Mao,Siqi Lan et al.
Deng Tang et al.
Early-onset colorectal cancer (EOCRC), defined as colorectal cancer diagnosed before the age of 50 years, is increasing worldwide, with a similar trend emerging in China. However, the clinicopathological and mismatch repair features of EOCR...
DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management [0.03%]
Wilms瘤的DNA甲基化和转录组谱系揭示了肿瘤分层和管理相关的新的失调基因和表观遗传过程
Abu Saadat,Francesco Cecere,Federica Rossetti et al.
Abu Saadat et al.
Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute t...
The Optimal Lung Cancer Ct Screening Strategy: A Cost-Effectiveness Study Incorporating Nelson Evidence, Evolving Cost of Treatment and Smoking Cessation Interventions [0.03%]
基于Nelson证据和吸烟干预的肺癌CT筛查最优策略的成本效益分析研究
Koen de Nijs,Kevin Ten Haaf,Dana Moldovanu et al.
Koen de Nijs et al.
Lung cancer screening implementation is taking shape worldwide. Programme design requires specifying eligibility criteria, screening interval, and the optimal age range. We estimate benefits and harms of competing strategies, integrating NE...