Toward Personalized Neuroscience: Evaluating Individual-Level Information in Neural Mass Models [0.03%]
迈向个性化神经科学：评估神经质量模型中的个体层面信息
Carlotta B C Barkhau,Clemens Pellengahr,Zheng Wang et al.
Carlotta B C Barkhau et al.
Macroscale brain modeling using neural mass models (NMMs) offers a framework for simulating human whole-brain dynamics. These models are pivotal for investigating the brain as a complex dynamic system, exploring phenomena like bifurcations,...
Lateralization Disruption and Dynamic Balance Alterations in Alzheimer's Disease: Impacts on Hemispheric Interaction and Cognitive Performance [0.03%]
阿尔茨海默病的半球功能失衡及动态平衡障碍对其半球间相互作用和认知表现的影响
Juan Wang,Yuxin Li,Yu Yang et al.
Juan Wang et al.
Brain lateralization is considered evolutionarily adaptive. Impaired functional specialization is thought to cause abnormal lateralization in neurological disorders. However, the dynamic changes in brain laterality in Alzheimer's disease (A...
Diffusion MRI Microstructure Markers of Changes in the Human Brain Across the Lifespan Using Constrained Spherical Deconvolution and Fixel-Based Techniques [0.03%]
基于约束球面卷积和像素技术的扩散MRI微结构标志物在人类一生中大脑变化的研究
Benjamin T Newman,John D Van Horn,T Jason Druzgal
Benjamin T Newman
Understanding how the brain develops, matures, ages, and declines is one of the fundamental questions facing neuroscience. This study uses 3-tissue constrained spherical deconvolution (3T-CSD) and more recently developed fixel-based derivat...
Association of Choroid Plexus Dysfunction and Cognitive Decline in Preeclampsia: Using T1WI Imaging, Quantitative Susceptibility Mapping and Deep-Learning-Based Segmentation [0.03%]
T1加权成像、定量磁敏感加基于深度学习的分割在子痫前期脑室脉络丛功能障碍及认知损害中的应用研究
Boyao Chen,Meng Li,Linfeng Yang et al.
Boyao Chen et al.
Preeclampsia is a severe pregnancy complication that can cause brain injury, yet early detection of related cognitive deficits remains challenging. Therefore, in order to investigate alterations in choroid plexus volume (CPV) and susceptibi...
Utility of Harmonisation for Fixel-Based Metrics in Travelling Subjects and Alzheimer's Disease Data [0.03%]
基于固定体素的度量在旅行受试者和阿尔茨海默病数据中的协调作用分析
Rui Zou,Koji Kamagata,Remika Mito et al.
Rui Zou et al.
Fixel-based analysis (FBA) is an advanced diffusion MRI analysis technique that facilitates the evaluation of white matter microstructure within 'fixels' (specific fibre populations within a voxel). In recent years, FBA has gained prominenc...
Multicenter Study
Human brain mapping. 2025 Nov;46(16):e70408. DOI:10.1002/hbm.70408 2025
Spatial Dissociation of Atrophy and Hypophysiology in Alzheimer's Disease: Implications for Biomarkers [0.03%]
阿尔茨海默病萎缩和垂体生理空间分离的解体标志物意义研究
Annie Dang,Di Wang,Jonathan M Towne et al.
Annie Dang et al.
The Amyloid/Tau/Neurodegeneration (A/T/N) biomarker framework is used for in vivo pathological profiling of Alzheimer's disease. A binary (+/-) label is assigned for each pathology (A, T, N) based on its presence or absence as determined by...
Age-Related Changes in the Amygdala From In Utero to Early Childhood: Association With Social and Cognitive Outcomes [0.03%]
胎儿期至学龄前杏仁核的年龄变化及其与社会行为和认知发育的关系
Megan E Mueller,Emily S Nichols,Sarah Al-Saoud et al.
Megan E Mueller et al.
The amygdala is a key element of the limbic system. It is involved in emotional processing controlling responses to social, affective, or motivational stimuli, facilitating interaction with the surrounding environment. Given its importance ...
Wired to Regulate: Brain Connectivity Predicts Emotion Regulation Capacity and Tendency [0.03%]
思维的自我调节：脑网络的连接性预测情绪调控能力及其倾向性
C Morawetz,M Hajrić,R A Rammensee et al.
C Morawetz et al.
Emotion regulation relies on the flexible coordination of neural networks involved in strategy selection and implementation. While previous studies have focused on task-related brain activity, the role of intrinsic, resting-state connectivi...
Brain Connectivity Gradients Alterations in Discordant Cerebrospinal Fluid Profile for Alzheimer's Disease Biomarkers [0.03%]
阿尔茨海默病生物标志物脑脊液谱型不一致相关的脑连接组变化模式
Lorenzo Pini,Chiara Tuzzato,Alessandra Griffa et al.
Lorenzo Pini et al.
Alzheimer's disease (AD) is a heterogeneous disorder characterized by brain accumulation of amyloid-beta (Aß, simplified as A for the AD biological model) and tau (T) proteins, with Aß emerging first. However, a significant proportion of ...