Minji Jung,Xiaoyu Wang,Sun Y Jeon et al.
Minji Jung et al.
Background: Metabolic dysregulation may contribute to kidney cancer development through shared biological mechanisms and/or as an independent risk factor. However, evidence on this association in the US population remains...
Samantha D Martin,Danial Pitafi,Florence Bourgeois et al.
Samantha D Martin et al.
Background: Attrition of new therapies is a major concern in oncology drug development. Little is known about subsequent drug development milestones once an oncology agent has entered clinical testing in children and adol...
Eligibility criteria for cancer drug trials in adult patients: Evidence from China, 2013-2021 [0.03%]
Zhuo Ma,Yichen Zhang,Dingyi Chen et al.
Zhuo Ma et al.
Background: Eligibility criteria used in cancer clinical trials ensure internal validity but may restrict enrollment and limit external generalizability. The US National Cancer Institute (NCI) has recommended broader crit...
Lei Li,Nan Song,Depu Zhang et al.
Lei Li et al.
Background: Large-scale studies of germline variants in hereditary cancer susceptibility genes among Chinese epithelial ovarian cancer (EOC) patients remain limited. This study assessed the prevalence and clinical signifi...
Multicenter Study
Cancer. 2026 May 1;132(9):e70395. DOI:10.1002/cncr.70395 2026
Neoadjuvant chemotherapy for soft-tissue sarcoma of the extremities: A post-hoc Sarculator-based risk analysis of the EORTC 62961-ESHO 95 randomized trial [0.03%]
Markus Albertsmeier,Valeria Milani,Lars H Lindner et al.
Markus Albertsmeier et al.
Background: In the EORTC 62961-ESHO 95 randomized trial (European Organization for Research and Treatment 62961-European Society of Hyperthermia Oncology 95; ClinicalTrials.gov identifier NCT00003052), neoadjuvant chemoth...
Randomized Controlled Trial
Cancer. 2026 May 1;132(9):e70427. DOI:10.1002/cncr.70427 2026
Cost-effectiveness of interventions to increase colorectal cancer screening among populations with low screening uptake [0.03%]
Florence K L Tangka,Sujha Subramanian,Sonja Hoover et al.
Florence K L Tangka et al.
Background: The decrease in colorectal cancer (CRC) mortality over the past 2 decades is largely attributed to increased screening. This progress has not been evenly distributed across populations. Individuals who seek ca...
Acute myeloid leukemia after myeloproliferative neoplasms: Real-world outcomes in the new treatment era in the United States [0.03%]
Jan Philipp Bewersdorf,Rong Wang,Lourdes Mendez et al.
Jan Philipp Bewersdorf et al.
Background: Progression to acute myeloid leukemia (AML) is a rare complication of myeloproliferative neoplasms (MPNs) with limited treatment options and median overall survival (OS) of 3-6 months. The treatment of AML has...
Fianlimab, a human lymphocyte activation gene-3 monoclonal antibody, in combination with cemiplimab: Tumor-specific expansion cohorts in advanced malignancies [0.03%]
Tae Min Kim,Stephen K Williamson,Kyriakos P Papadopoulos et al.
Tae Min Kim et al.
Background: The dose escalation phase of a first-in-human (FIH) study demonstrated acceptable safety and preliminary antitumor activity of fianlimab (anti-lymphocyte activation gene-3 [LAG-3]) as monotherapy and in combin...
Clinical Trial
Cancer. 2026 May 1;132(9):e70396. DOI:10.1002/cncr.70396 2026
Poverty in the residential and surrounding counties and its impact on mortality in women with breast cancer [0.03%]
Ifeoma Nwigwe,Ramkrishnan V Tenkasi,Michael R Desjardins et al.
Ifeoma Nwigwe et al.
Background: The influence of poverty on cancer outcomes beyond a woman's county of residence remains understudied, despite individuals frequently interacting within a larger ecosocial system. ...
Disability-adjusted life-years from human papillomavirus-related oral cavity and pharynx cancers in US men, 2017-2021 [0.03%]
2017至2021年美国男性与人乳头瘤病毒相关的口腔和咽部癌症的伤残调整寿命年
Harshank V Patel,Madison C Laird,Michael D Crone et al.
Harshank V Patel et al.
Background: Squamous cell oropharyngeal cancer (OPC) incidence in men has surpassed cervical cancer in women as the most common cancer linked to high-risk human papillomavirus (HPV). However, vaccine uptake remains subopt...