Andrew D Folkerts,Lauren M Janczewski,Ryan P Merkow
Andrew D Folkerts
Colorectal cancer is the third most common cancer diagnosed in the United States, with an anticipated 53,000 deaths from this disease in 2025. Greater than one in five patients will present with synchronous colorectal liver metastases (CRLM...
5-fluoro-deoxyglucose PET/CT response after neoadjuvant chemotherapy predicts long-term outcomes in soft tissue sarcomas: Results from a prospective trial [0.03%]
新辅助化疗后18F-氟脱氧葡萄糖正电子发射断层扫描/计算机体层摄影响应可预测软组织肉瘤长期预后：一项前瞻性试验的结果
Edward Y Cheng,Andrea P Espejo Freire,Juan C Manivel et al.
Edward Y Cheng et al.
Background: Only 30%-40% of high-grade sarcomas respond to initial chemotherapy, which can have significant toxicities. Computed tomography imaging alone has limitations in evaluating treatment response. Imaging with 5-fl...
Incidence of chronic medical conditions among survivors of adolescent and young adult cancer compared to a population without cancer [0.03%]
与无癌症人群相比，青少年及年轻成人癌症幸存者的慢性疾病发生率分析
Theresa H M Keegan,Renata Abrahão,Jessica Chubak et al.
Theresa H M Keegan et al.
Background: Few studies have assessed the burden of chronic medical conditions in adolescent and young adult (AYA) cancer survivors. This study estimated the risk of these conditions among AYA survivors compared to a matc...
Comparative Study
Cancer. 2025 Oct 15;131(20):e70125. DOI:10.1002/cncr.70125 2025
From treatment escalation to ultra de-intensification: When androgen-deprivation therapy alone remains a rational choice in metastatic hormone-sensitive prostate cancer [0.03%]
从治疗升级到极度减毒治疗：在转移性雄激素敏感前列腺癌的情况下仅使用雄激素剥夺治疗的合理性探讨
Giandomenico Roviello,Martina Catalano,Lorenzo Antonuzzo
Giandomenico Roviello
Reply to "From treatment escalation to ultra de-intensification: When androgen-deprivation therapy alone remains a rational choice in metastatic hormone-sensitive prostate cancer" [0.03%]
对《从治疗升级到超强减化治疗：在激素敏感性前列腺癌去势治疗单药足矣吗？》一文的回应
Irene Tsung,Zachery R Reichert,Suresh S Ramalingam
Irene Tsung
Multilevel challenges and adaptations to patient navigation programs for colorectal cancer screening and follow-up: Findings from the Accelerating Colorectal Cancer Screening and follow-up through Implementation Science consortium [0.03%]
结直肠癌筛查和随访的多级挑战与患者导航项目调整：通过实施科学加速结直肠癌筛查和随访联盟的结果
Gloria D Coronado,Priyanka Gautom,Jennifer L Schneider et al.
Gloria D Coronado et al.
Background: Patient navigation services can substantially boost participation in colorectal cancer screening and follow-up. As part of the Accelerating Colorectal Cancer Screening and follow-up through Implementation Scie...
Efficacy and safety of OB756 (a novel selective JAK2 inhibitor) for essential thrombocythemia in patients intolerant of or resistant to hydroxyurea or intolerant of interferon: A phase 2, open-label, multicenter study [0.03%]
OB756(一种新型选择性JAK2抑制剂)治疗羟基脲不耐受或耐药及干扰素不耐受的原发性血小板增多症患者疗效和安全性：一项二期、开放性、多中心临床研究
Jian Huang,Rumeng Li,Tiejun Gong et al.
Jian Huang et al.
Background: OB756 is a novel oral selective JAK2 inhibitor targeting the JAK-STAT pathway. This study assessed its safety and efficacy in patients with essential thrombocythemia (ET) who were resistant to or intolerant of...
Clinical Trial
Cancer. 2025 Oct 15;131(20):e70101. DOI:10.1002/cncr.70101 2025
Genome-wide association analysis identifies fucosyltransferase 2 variants associated with pancreatic intraductal papillary mucinous neoplasms [0.03%]
全基因组关联分析确定了与胰腺导管内乳头状黏液性肿瘤相关的FUT2变异体
Apostolos Gaitanidis,Carlos Fernandez-Del Castillo,Shravya Srinivas Rao et al.
Apostolos Gaitanidis et al.
Background: Intraductal papillary mucinous neoplasms (IPMNs) are common pancreatic cystic neoplasms. Observation or surgical resection in patients with high-risk IPMNs is recommended because there is a risk of malignant t...