Bone Metastasis Distribution Matters: Prognostic Effect of the Axial-to-Peripheral Ratio in Metastatic Hormone-Sensitive Prostate Cancer [0.03%]
骨转移的位置很重要：轴位与外周骨转移比例在转移性激素敏感型前列腺癌中的预后价值研究
Ali Fuat Gürbüz,Murat Araz,Hacer Demir et al.
Ali Fuat Gürbüz et al.
Background: Bone metastases represent the dominant pattern of spread in metastatic hormone-sensitive prostate cancer (mHSPC). Current prognostic classifications mainly rely on metastatic burden defined by lesion number or...
Challenging the Evolving Nomenclature of Ultrasound-Guided Transperineal Prostate Biopsy: A Call for Standardization [0.03%]
挑战经直肠超声引导的前列腺靶向穿刺活检命名法并呼吁标准化命名法
Pedro Ivo C Ravizzini,Luis Fernando Delmonte,Victor Arthur G Valdo et al.
Pedro Ivo C Ravizzini et al.
Background: The rapid global adoption of ultrasound-guided transperineal prostate biopsy has been accompanied by inconsistent nomenclature, particularly surrounding the term "freehand." This lexical imprecision creates co...
Review
The Prostate. 2026 Apr 8. DOI:10.1002/pros.70170 2026
Genomic Prostate Score (GPS) as a Prognostic Biomarker in Patients With Localized Prostate Cancer Undergoing Focal Therapy [0.03%]
基因组前列腺评分(GPS)作为局灶治疗的局部前列腺癌患者的预后生物标志物
Sriram Deivasigamani,Srinath Kotamarti,Mahdi Mottaghi et al.
Sriram Deivasigamani et al.
Background: Focal therapy (FT) encompasses ablation of the prostate cancer (PCa) while preserving the surrounding benign tissue, aiming to minimize or spare patients from postoperative complications. Although FT has been ...
A Two-Factor Bedside Prognostic Score Integrating Eastern Cooperative Oncology Group (ECOG) Performance Status and Aggressive Metastatic Burden in Metastatic Hormone-Sensitive Prostate Cancer [0.03%]
一项结合东部协作组肿瘤学组（ECOG）体能状态和侵袭性转移负担的二线预后评分在转移性激素敏感型前列腺癌中的作用
Koichiro Kurokawa,Satoshi Yamamoto,Yasutaka Yamada et al.
Koichiro Kurokawa et al.
Background: Metastatic hormone-sensitive prostate cancer (mHSPC) remains clinically heterogeneous despite upfront treatment intensification. The commonly used CHAARTED high-volume and LATITUDE high-risk criteria stratify ...
Is Saturation Biopsy Still a Viable Alternative to Fusion Biopsy in the Era of Multiparametric MRI? A Comparative Analysis in Patients With Prior Negative Biopsy [0.03%]
饱和活检在多参数MRI时代的融合活检的替代选择吗？对既往阴性活检患者的比较分析
Arda Taşkın Taşkıran,Yusuf Şenoğlu
Arda Taşkın Taşkıran
Background: We aimed to compare the diagnostic accuracy of transrectal ultrasound (TRUS)-guided saturation biopsy (SB) and multiparametric MRI (mpMRI)-TRUS fusion-guided combined biopsy (CB) in patients with prior negativ...
Global Trends in Prostate Cancer Incidence Among Men Aged 55+ (1992-2021): An Age-Period-Cohort Analysis [0.03%]
1992年至2021年全球55岁以上男性前列腺癌发病趋势（基于年龄、时期和队列的分析）
Xinling Han,Xuelian Zhao,Ning Zhang et al.
Xinling Han et al.
Background: With global population aging, lifestyle transitions, and the widespread expansion of screening practices, the burden of prostate cancer has shown complex geographical variations. The study aims to dissect the ...
Spatial Robustness of Prostate Cancer Biomarkers Evaluated by Spatial Transcriptomics [0.03%]
利用空间转录组学评估前列腺癌生物标志物的空间稳健性
Kristofer G Taylor,Bjarne Johannessen,Ian G Mills et al.
Kristofer G Taylor et al.
Background: Prognostic biomarker panels identified through bulk sequencing approaches have shown utility in localized prostate cancer but are limited by underlying molecular heterogeneity. Spatial transcriptomics offers a...
Development of Machine Learning Models for Predicting Prostate Cancer in Biopsy Candidates Using Prostate-Specific Antigen, Magnetic Resonance Imaging, and Hematologic Parameters [0.03%]
基于PSA、MRI和血液学参数的前列腺癌活检患者的机器学习模型构建及验证
Deniz Noyan Özlü,Yusuf Arıkan,Büşra Emir et al.
Deniz Noyan Özlü et al.
Introduction: Prostate-specific antigen (PSA) alone is insufficient for the diagnosis of prostate cancer (PCa), particularly within the gray zone range of 4-10 ng/mL. Multiparametric magnetic resonance imaging (mpMRI), al...
Socioeconomic and Demographic Factors in Genetic Testing Utilization Among Advanced Prostate Cancer Patients [0.03%]
晚期前列腺癌患者中影响基因检测利用的社会经济及人口因素分析
Alexandra T Skowron,Karen Childers,Courtney M Rose et al.
Alexandra T Skowron et al.
Purpose: Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized and hypothesized to be impacted by socioeconomic and demographic factors. This single institution, retrospective study ass...
Impact of Intraprostatic Simultaneous Integrated Boost on Long-Term Outcomes in Unfavorable Intermediate-Risk Prostate Cancer Treated With Dose-Escalated Radiotherapy and Short-Term Androgen Deprivation Therapy [0.03%]
立体定向根治性放疗联合短期雄激素剥夺治疗不利中危前列腺癌的长期疗效及预后因素分析
Cem Onal,Aysenur Elmali,Birhan Demirhan et al.
Cem Onal et al.
Background: Unfavorable intermediate-risk prostate cancer (UIR-PCa) represents a biologically heterogeneous subgroup with a higher risk of recurrence compared with favorable intermediate-risk disease. Contemporary managem...