Treatment of Hot Flashes in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy [0.03%]
前列腺癌男性患者雄激素剥夺治疗期间潮热的治疗
Ellen Lund Schaldemose,Mads Hvid Poulsen,Bettina Nørby et al.
Ellen Lund Schaldemose et al.
Background: Hot flashes are common and often debilitating side effects of castration therapy; a cornerstone in the treatment of metastatic prostate cancer (PCa) as well as in localized or locally advanced PCa when combine...
Review
The Prostate. 2026 Aug 2. DOI:10.1002/pros.70229 2026
Comparisons of Novel Risk Stratification Models to the Current cT1a/b Staging in Incidental Prostate Cancer [0.03%]
新型风险分层模型与偶然发现的前列腺癌现行cT1a/b分期比较研究
Lukas Scheipner,Andrea Baudo,Letizia Maria Ippolita Jannello et al.
Lukas Scheipner et al.
Objective: Incidental prostate cancer (PCa) patients are currently stratified to either cT1a vs. cT1b stage, depending on tumor volume (< 5% vs. > 5%) in the resected tissue. We tested for other models that could improve ...
Clinical Impact of Gleason Pattern 5 on Doublet Versus Triplet Therapy in Metastatic Hormone-Sensitive Prostate Cancer [0.03%]
GLEASON 5级对转移性激素敏感性前列腺癌双联和三联治疗的临床影响
Saizo Fujimoto,Tsuyoshi Morita,Yutaka Yamamoto et al.
Saizo Fujimoto et al.
Background: Upfront treatment intensification with androgen deprivation therapy (ADT) plus an androgen receptor pathway inhibitor has become a standard approach for metastatic hormone-sensitive prostate cancer (mHSPC). Ho...
Thomas McMaster,Caitlin Ying Ming Louey,Jordan Santucci et al.
Thomas McMaster et al.
Background: Prostate-specific membrane antigen positron emission tomography (PSMA-PET) is reshaping nodal staging in prostate cancer by detecting regional lymph node metastases with greater accuracy than conventional imag...
Review
The Prostate. 2026 Aug 2. DOI:10.1002/pros.70231 2026
Predictive Value of [-2]proPSA-Related Indices for Prostate Cancer Detection Years Before Prostate-Specific Antigen Elevation: Insights From a Five-Year Longitudinal Screening Cohort [0.03%]
[-2]proPSA相关指标预测前列腺特异性抗原升高前几年检测前列腺癌的价值：一项五年纵向筛查队列的启示
Yoshitaka Sekine,Yuji Fujizuka,Syun Nakazawa et al.
Yoshitaka Sekine et al.
Background: [-2]proPSA(p2PSA)-related indices have demonstrated diagnostic value for detecting prostate cancer (PC) in males with modest increases in prostate-specific antigen levels (PSA) of < 10 ng/mL. However, the "lea...
Evaluation of [225Ac]Ac-PSMA-617 vis-a-vis Rechallenge [177Lu]Lu-PSMA-617 PRLT Versus Cabazitaxel or Oral Metronomic Chemotherapy in mCRPC: An Observational Analysis of Outcome and Toxicity Profiles in a Real-World Clinical Scenario [0.03%]
[225Ac]Ac-PSMA-617与复方[177Lu]Lu-PSMA-617 PRLT vs. 卡巴他赛或口服微量化疗治疗mCRPC：真实世界临床场景下的疗效和毒副反应观察分析
Roopal Agrawal,Rahul V Parghane,Amit Joshi et al.
Roopal Agrawal et al.
Introduction: A subset of prostate cancer progresses to aggressive state of metastatic castration-resistant prostate cancer (mCRPC), wherein multiple therapeutic options demonstrate limited success rates. In this observat...
Intense Focal Peripheral Uptake Pattern on 18F-PET/PSMA as a Predictor of Histological Upgrading in Prostate Cancer [0.03%]
前列腺癌中18F-PET/PSMA的强烈周边摄取模式可作为病理升级预测因子
Carlos Alexis González-Martínez,Jorge Augusto Alcacio-Mendoza,Rodrigo Hernández-Ramírez et al.
Carlos Alexis González-Martínez et al.
Background: Intraprostatic uptake patterns on 18F-PET/PSMA, such as those defined by the PRIMARY score, have been associated with clinically significant prostate cancer. However, the value of the peripheral focal intense ...
Prognostic Significance of the Modified Glasgow Prognostic Score and Systemic Immune-Inflammation Index in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Cabazitaxel [0.03%]
多西他赛治疗转移性去势抵抗性前列腺癌患者改良版格拉斯哥预后评分和全身免疫炎症指数的预后价值
Kotaro Suzuki,Junichiro Hirata,Hideto Ueki et al.
Kotaro Suzuki et al.
Background: The modified Glasgow Prognostic Score (mGPS) and systemic immune-inflammation index (SII) are useful prognostic markers for various malignancies. This study aimed to evaluate their prognostic significance in p...
Evaluating Risk Factors Associating With Late Recurrence After Low-Dose-Rate Brachytherapy for Prostate Cancer Using Machine Learning [0.03%]
利用机器学习评估低剂量率组织间植入治疗前列腺癌后晚期复发的相关危险因素
Kenta Onishi,Tomonori Nakahama,Yasushi Nakai et al.
Kenta Onishi et al.
Background: The Phoenix definition is widely used to define biochemical recurrence (BCR) after radiation therapy for prostate cancer; however, a definitive definition of cure remains unclear. This study aimed to identify ...
A Triple Clinical Filter Model for Selective Omission of Systematic Cores in Transperineal Cognitive Prostate Biopsy: A Retrospective Observational Study [0.03%]
一种针对经会阴认知前列腺活检选择性省略系统核心的三重临床过滤模型：一项回顾性观察研究
Muhammed Zübeyr Canbolat,İsa Dağlı,Tuncel Uzel et al.
Muhammed Zübeyr Canbolat et al.
Background: To determine whether systematic biopsy can be safely omitted in selected patients undergoing antibiotic-free transperineal cognitive MRI-targeted prostate biopsy under local anesthesia, and to identify clinica...