Influence of pelvic lymph node dissection and node-positive disease on biochemical recurrence, secondary treatment, and survival after radical prostatectomy in men with prostate cancer [0.03%]
盆腔淋巴结清扫和阳性淋巴结对前列腺癌根治术后生化复发，二次治疗和生存期的影响分析
Samuel L Washington rd,Janet E Cowan,Annika Herlemann et al.
Samuel L Washington rd et al.
Background: The benefit of pelvic lymph node dissection (PLND) at radical prostatectomy (RP) remains unclear given the low prevalence of known nodal disease (pN1) and concerns about its therapeutic utility. ...
Spine metastasis in patients with prostate cancer: Survival prognosis assessment [0.03%]
前列腺癌患者的脊柱转移：生存预后评估
Aymeric Amelot,Louis-Marie Terrier,Louis-Romée Le Nail et al.
Aymeric Amelot et al.
Background: Patients presenting spine metastasis (SpM) from prostate cancer (PC) form a heterogeneous population, through this study, we aimed to clarify and update their prognostic assessment. ...
Androgen receptor signaling-targeted therapy and taxane chemotherapy induce visceral metastasis in castration-resistant prostate cancer [0.03%]
雄激素受体信号通路靶向治疗和紫杉烷化疗在去势抵抗性前列腺癌中诱导内脏转移
Hiroaki Iwamoto,Kouji Izumi,Takashi Shimada et al.
Hiroaki Iwamoto et al.
Background: Visceral metastasis (VM), an important poor prognostic factor of prostate cancer (PC), is not commonly observed in castration sensitive status but is often observed after castration-resistant progression. Howe...
Neuropeptide Y nerve paracrine regulation of prostate cancer oncogenesis and therapy resistance [0.03%]
神经肽Y神经旁分泌调控前列腺癌的发生和耐药性
Yi Ding,MinJae Lee,Yan Gao et al.
Yi Ding et al.
Background: Nerves are key factors in prostate cancer (PCa) progression. Here, we propose that neuropeptide Y (NPY) nerves are key regulators of cancer-nerve interaction. ...
CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage [0.03%]
CHD1和SPOP协同保护前列腺上皮细胞免受DNA损伤
Yini Zhu,Jiling Wen,Gang Huang et al.
Yini Zhu et al.
Background: Recent genomic profiling has identified a subtype of prostate cancer (PCa) characterized by two key genetic alterations: missense mutation of speckle-type POZ protein (SPOP) and homozygous deletion of chromodo...
Association between CD8 and PD-L1 expression and outcomes after radical prostatectomy for localized prostate cancer [0.03%]
CD8和PD-L1表达与局灶前列腺癌根治性前列腺切除术后结局之间的关联
Cecile Vicier,Praful Ravi,Lucia Kwak et al.
Cecile Vicier et al.
Background: Characterization of markers of both immune suppression and activation may provide more prognostic information than assessment of single markers in localized prostate cancer. We therefore sought to determine th...
Association between PSA density and pathologically significant prostate cancer: The impact of prostate volume [0.03%]
PSA密度与病理显著前列腺癌之间的联系：前列腺体积的影响
Nativ Omri,Malshy Kamil,Kastin Alexander et al.
Nativ Omri et al.
Background: The early diagnosis of prostate cancer (PCa) is mainly based on prostate-specific antigen (PSA) blood levels and digital rectal examination. However, this approach may result in a high rate of negative biopsie...
Effect of Eriocalyxin B on prostatic inflammation and pelvic pain in a mouse model of experimental autoimmune prostatitis [0.03%]
埃里微紫花前素B对实验性自身免疫性前列腺炎小鼠模型的前列腺炎症和盆腔疼痛的影响
Li-Gang Zhang,Zi-Qiang Yu,Cheng Yang et al.
Li-Gang Zhang et al.
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disease in males. Eriocalyxin B (EriB), a natural diterpenoid purified from Isodon eriocalyx var. laxiflora, was previously reported to ha...
18 F-labeled 1,2,3-triazole-linked Glu-urea-Lys-based PSMA ligands have good pharmacokinetic properties for positron emission tomography imaging of prostate cancer [0.03%]
基于18F标记的1,2,3-三唑连接的Glu-尿素-Lys的PSMA配体在前列腺癌正电子发射断层成像中具有良好的药代动力学特性
Byoung Se Lee,So Young Chu,Woon Jung Jung et al.
Byoung Se Lee et al.
Background: Prostate-specific membrane antigen (PSMA) is increasingly recognized as an excellent target for prostate cancer imaging and therapy. Finding compounds with a high target-to-nontarget ratio are an important cha...
Sudden PSA rise to ≥20 ng/ml and prostate cancer diagnosis in the United States: A population-based study [0.03%]
PSA水平突然升高至≥20ng/ml与美国前列腺癌诊断：一项人群研究
Fernandino L Vilson,Shufeng Li,James D Brooks et al.
Fernandino L Vilson et al.
Purpose: While prostate-specific antigen (PSA) screening protocols vary, many clinicians have anecdotes of screened men with low PSA levels that rise significantly and are associated with high-risk prostate cancer (PC). W...