digitalMALDI: A Single-Particle-Based Mass Spectrometric Detection System for Biomolecules [0.03%]
数字MALDI：一种基于单颗粒的生物分子质谱检测系统
Dapeng Chen,Wayne A Bryden,Michael McLoughlin et al.
Dapeng Chen et al.
The development of a real-time system for characterizing individual biomolecule-containing aerosol particles presents a transformative opportunity to monitor respiratory conditions, including infections and lung diseases. Existing molecular...
Allen Martin,Alena N Joignant,Matt Farrell et al.
Allen Martin et al.
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a class of emerging contaminants that have been in use industrially since the 1940s. Their long-term and extensive commercial use has led to their ubiquitous presence in the environme...
Sodiation of Enhanced Green Fluorescent Protein (EGFP) in Basic Solution Studied by Electrospray Mass Spectrometry [0.03%]
电喷雾质谱研究碱性溶液中增强型绿色荧光蛋白(EGFP)的钠化反应
Kenzo Hiraoka,Satoshi Ninomiya,Stephanie Rankin-Turner et al.
Kenzo Hiraoka et al.
In our previous work, the sodiation of melittin, cytochrome c, and ubiquitin in a 1 mM NaOH water/methanol solution was studied by electrospray mass spectrometry. It was suggested that the α-helix is more resistant to sodiation than the β...
Application of Online Multi-Internal Standard Calibration for Determination of Iodine by ICP-MS [0.03%]
在线多内标法用于ICP-MS测定碘的应用研究
Long-Hua Zhou,Xing-Chen Lin,Li-Li Suo et al.
Long-Hua Zhou et al.
This study presents a comprehensive evaluation of the application of online multi-internal standard calibration (M.ISC) in determining iodine concentrations through inductively coupled plasma mass spectrometry (ICP-MS). Notably, M.ISC strea...
Bothersome Back Exchange in MALDI Plume and Its Impact on Hydrogen/Deuterium Exchange Mass Spectrometry Analysis [0.03%]
基质辅助激光解吸电离(MALDI)离子源中的反向回流及其对氢氘交换质谱分析的影响
Xianwen Lou,Michel van Houtem,René P M Lafleur et al.
Xianwen Lou et al.
One critical issue in hydrogen/deuterium exchange mass spectrometry (HDX MS) analysis is the deleterious back exchange. Herein, we report that when matrix-assisted laser desorption/ionization (MALDI) is used, the MALDI process itself can al...
Cryogenic TOF-SIMS Around Sublimation Temperature of Quench-Condensed Noble Gas (Ne, Ar, and Kr) Films [0.03%]
次临界升华温度下惰性气体（Ne、Ar和Kr）淬火凝聚薄膜的低温TOF-SIMS分析
Taku T Suzuki
Taku T Suzuki
A possible TOF-SIMS analysis of surface phase transitions has recently been proposed for limited cases such as polymers and ionic liquids. In the present study, we have extended this analysis to quench-condensed noble gas films. The newly d...
Performance Optimization of a Large Geometry High Resolution-Secondary Ion Mass Spectrometer (HR-SIMS) for High Precision Measurements of Oxygen Isotopic Composition (δ18O) and U-Pb Geochronology in Zircon [0.03%]
大型几何高分辨率二次离子质谱仪（HR-SIMS）的性能优化在锆石中的氧同位素组成（δ18O）和U-Pb定年中的精准测量中的应用
Deeksha Khandelwal,Pankaj Kumar,P V Kumar et al.
Deeksha Khandelwal et al.
A large geometry high resolution secondary ion mass spectrometer (HR-SIMS) has been established as a part of the National Geochronology Facility (NGF) at Inter-University Accelerator Centre (IUAC), New Delhi. The performance of the instrume...
Ghost Peaks of Aromatic Metabolites Induced by Corona Discharge Artifacts in LC-ESI-MS/MS [0.03%]
LC-ESI-MS/MS分析中由冠状放电伪影引起的芳香代谢物的鬼峰
Yayoi Hongo,Daisuke Fukuyama,Lee Chuin Chen et al.
Yayoi Hongo et al.
LC-ESI-MS/MS is a preferred method for detecting and identifying metabolites, including those that are unpredictable from the genome, especially in basal metazoans like Cnidaria, which diverged earlier than bilaterians and whose metabolism ...
Molecular Ion: An Extended, Fully Collective, and More Contemporary Definition [0.03%]
分子离子的扩展定义：整体性、全面性和时代感更强的新视角
Caroline P Carvalho,Thiago C Canevari,Marcos N Eberlin
Caroline P Carvalho
Tian Autumn Qiu
Tian Autumn Qiu
The spatial information of xenobiotics distribution, metabolism, and toxicity mechanisms in situ has drawn increasing attention in both pharmaceutical and environmental toxicology research to aid drug development and environmental risk asse...