Peace Emele,Paul M Mayer
Peace Emele
Protonated aldehydes can be formed in the gas phase by proton-transfer reactions with atmospheric water. This work explored the unimolecular chemistry of protonated aldehydes in the gas phase using tandem mass spectrometry and theory, focus...
Editorial: Artificial Intelligence in Ion Mobility Spectrometry-Mass Spectrometry for Omics Research [0.03%]
omics研究中基于人工智能的离子淌度谱-质谱方法学及其应用评论文章
Aivett Bilbao,Xueyun Zheng
Aivett Bilbao
Top-Down Proteomics of Skinned Human Muscle Fibers Reveals Proteoform-Resolved Fiber-to-Fiber Variability [0.03%]
对去皮的人类肌纤维的自上而下蛋白质组学分析揭示了蛋白变体解析下的肌纤维间差异性
Mallory C Wilson,Zhan Gao,Justin R Lopez et al.
Mallory C Wilson et al.
Human skeletal muscle is composed of highly heterogeneous single muscle fibers (multinucleated single cells) that are commonly classified as fast or slow fiber types, yet proteoform-resolved characterization of individual human muscle fiber...
Investigation of the Protective Effect of Stemona Alkaloids on Acute Lung Injury via LC-MS/MS-Based Sphingolipid Metabolomic Profiling [0.03%]
基于LC-MS/MS的鞘脂代谢组学谱图研究尺翰生物碱对急性肺损伤保护作用
Hang Ma,Yao Qin,Chang Su et al.
Hang Ma et al.
The dried roots of S. tuberosa (known as "Baibu" in traditional Chinese medicine) have long been used for the treatment of pulmonary infections. Alkaloids are recognized as the principal bioactive constituents underlying their therapeutic e...
Data-Independent Acquisition Enhancement of a Competitive Activity-Based Protein Profiling Platform for Kinase Inhibitor Screening [0.03%]
一种用于激酶抑制剂筛选的具有竞争力的基于活性的蛋白质图谱平台的数据非依赖性采集增强方法
Ravi Tharakan,Yanyan Qu,Michele Ceribelli et al.
Ravi Tharakan et al.
Kinase inhibitors represent a vital class of therapeutic agents widely used in cancer research, immunology, and other disease areas. Mass spectrometry (MS) employing specially designed small-molecule kinase-binding probes has become an esse...
Advances in Mass Spectrometry Instrumentation and Methodology for Analysis of Alternative Protein Isoforms [0.03%]
用于替代蛋白质异构体分析的质谱仪器和方法学研究进展
Micah D Lehe,Raghad Almofeez,Erin D Jeffery et al.
Micah D Lehe et al.
Proteoforms represent the many final protein products that can be generated by a protein-coding gene. A key source of proteomic variation is alternative splicing (AS), with at least 90% of human genes undergoing AS to cause protein sequence...
HPLC-MS/MS Method for Monitoring of L-Asparaginase Activity by Using Asparagine and Aspartic Acid Plasma Levels [0.03%]
基于血浆天冬酰胺和天冬氨酸水平测定L-天冬酰胺酶活性的LC-MS/MS方法
Cem Kaplan,İbrahim Daniş,Durişehvar Özer Ünal
Cem Kaplan
The effectiveness of L-asparaginase and therefore the effectiveness of acute lymphoblastic leukemia treatment will be understood by determining the substrates of the enzyme, L-asparagine and L-glutamine. For this purpose, the high-performan...
PSLite Online: A Portable, Modern Web Application to Analyze Top-Down Mass Spectrometry Fragmentation Data [0.03%]
PSLite在线版：一个便携的现代网络应用，用于分析顶部向下质谱裂解数据
Ryan T Fellers,Joseph B Greer,Bryan P Early et al.
Ryan T Fellers et al.
PSLite Online is a modern, web-based application designed to facilitate the analysis of top-down mass spectrometry fragmentation data, particularly for targeted proteoform studies. As a successor to the Windows-only ProSight Lite, PSLite On...
Selected Ion Flow-Tube Mass Spectrometry (SIFT-MS) of Mo(CO)6 and W(CO)6 Vapours With Positive and Negative Reagent Ions [0.03%]
用正、负试剂离子研究Mo(CO)6和W(CO)6蒸汽的选定离子流动管质谱(SIFT-MS)
Kseniya Dryahina,Patrik Španěl,Stanislav Musil et al.
Kseniya Dryahina et al.
Selected ion flow-tube mass spectrometry (SIFT-MS) was used to characterise the gas-phase ion-molecule reactions of the eight standard reagent ions H3O+, NO+, O2 +˙, OH-, O-˙, O2 -˙, NO2 - and NO3 - with molybdenum and tungsten hexacarbo...
High-Resolution MS/MS Characterization of Vine Leaf Flavonols and Flavanonols of Fungal-Resistant Varieties [0.03%]
高分辨率质谱表征抗真菌品种葡萄叶黄酮醇和黄烷醇
Mirko De Rosso,Roberto Carraro,Itay Maoz et al.
Mirko De Rosso et al.
In viticulture, major challenges such as the effects of climate change and the use of phytochemicals to control grapevine pathogens can be mitigated by using vine varieties that are highly tolerant to fungal diseases and suitable for cultiv...