Expression of the extracellular electron transfer pathway of Acidithiobacillus ferrooxidans enabling Fe(III)-citrate reduction and anodic respiration in Escherichia coli [0.03%]
利用大肠杆菌呼吸菌株表达铁氧化细菌嗜酸硫铁菌的细胞外电子传递途径实现Fe(III)-柠檬酸还原和胞外呼吸作用
Helena Fuchs,Charlotte Ashworth-Güth,Gero Frisch et al.
Helena Fuchs et al.
Exoelectrogens are capable of transferring electrons through a defined route outside of the cell, making them ideal for microbial fuel cells, electrosynthesis and biosensing applications. Engineering well characterized hosts and transferrin...
Metabolic engineering of microbial pathways for 5-aminolevulinic acid biosynthesis: Recent advances and biotechnological applications [0.03%]
用于生物合成左旋谷氨酰胺酸的微生物代谢工程研究：近期研究成果和生物技术应用
Shahid Mahmood,Abdullah Arsalan,Muhammad Shoaib et al.
Shahid Mahmood et al.
5-Aminolevulinic acid (5-ALA) is a basic precursor in the bioproduction of tetrapyrrole compounds, such as heme, chlorophyll, and vitamin B12. Its extensive applications in agriculture, medicine, cosmetics and animal feed industry have garn...
Modular pathway engineering for enhancing terpenoid production in plants [0.03%]
模块化途径工程在植物中增强萜类化合物的生产
Yeo Jin Lee,Sun-Hwa Ha
Yeo Jin Lee
Terpenoids represent a structurally diverse and industrially valuable class of plant metabolites, encompassing mono-, sesqui-, di-, tri-, and tetraterpenoids, with broad applications in fragrances, pharmaceuticals, pigments, and beyond. In ...
Orthogonal quorum sensing circuits enable dynamic regulation in Escherichia coli [0.03%]
正交准度感知线路能够使大肠杆菌进行动态调节
Michael J Ream,Kristala L J Prather
Michael J Ream
Engineers have effectively employed quorum sensing (QS) in a variety of applications to dynamically regulate gene expression. Particular emphasis has been placed on the class of well-studied systems that use acyl homoserine lactones (AHL) a...
Bioprocess optimisation via joint machine learning and metabolic modelling [0.03%]
基于联合机器学习和代谢模型的生物工艺优化
Guido Zampieri,Viktor Sandner,Suraj Verma et al.
Guido Zampieri et al.
Optimisation of the design-build-test-learn cycle remains a bottleneck for developing and efficiently manufacturing the next generation of bioproducts. To address this challenge, research has traditionally focused on either data-driven or m...
Enabling supratheoretical isopropanol yields from carbon-negative glucose fermentations with a Clostridium acetobutylicum- Clostridium ljungdahlii coculture [0.03%]
利用Clostridium acetobutylicum-Clostridium ljungdahlii共培养体系从碳负值葡萄糖发酵中获得超理论异丙醇 yield
Noah B Willis,Jonathan K Otten,Hyeongmin Seo et al.
Noah B Willis et al.
Synthetic microbial cocultures, which combine the designed capabilities of multiple microbes into one process, have significant potential for sustainable production of fuels and chemicals. Most studies of defined cocultures have tested rela...
Single Cell Oil Enriched in Ricinoleic Acid Biosynthesis from Glucose via Metabolically Rewired Oleaginous Yeast [0.03%]
一种通过代谢重组的生脂酵母以葡萄糖为原料生物合成蓖麻油酸单细胞油脂的研究
Yizi Yu,Ran Lu,Mei-Li Sun et al.
Yizi Yu et al.
Ricinoleic acid, an industrially high-value hydroxy fatty acid traditionally sourced from castor seed oil. However, plant-based production is plagued by challenges such as inherent toxicity, environmental risks, and unstable supply. Microbi...
Engineering robust Saccharomyces cerevisiae for high-yield sabinene production from lignocellulosic hydrolysate [0.03%]
工程设计耐受性的酿酒酵母用于木质纤维素水解液高效高产右旋樟脑烯
Dong Meng,Shuai Wang,Xu Li et al.
Dong Meng et al.
Microbial synthesis of sabinene from lignocellulosic biomass represents a sustainable and green alternative to traditional production methods. However, achieving high productivity is often hampered by inefficient substrate utilization and s...
High-yield trichodermin production in Trichoderma taxi via in silico-driven exporter identification and systems metabolic engineering [0.03%]
基于计算驱动的转运蛋白鉴定及系统代谢工程策略高效生产曲霉素抗生素_trichodermin
Mingjian Luan,Bingbing Xie,Yu Wan et al.
Mingjian Luan et al.
Trichodermin, a sesquiterpenoid with notable antifungal, plant growth-regulating, and antitumor activities, holds broad application potential in medicine and agriculture. However, its low native production in Trichoderma presents a signific...
Combining Pathway Engineering and Precursor Enrichment to Build a Multi-Trait Soybean Platform for Aquaculture Feed Applications [0.03%]
结合途径工程和前体物富集构建用于水产饲料应用的多性状大豆平台
Hyojin Kim,Truyen Quach,Kiyoul Park et al.
Hyojin Kim et al.
Oilseed crops offer a scalable aquaculture feed production platform for generating oils with long-chain ω-3 polyunsaturated fatty acids and high-value antioxidants, but metabolic flux through heterologous pathways is often constrained by p...