Multiscale biophysical control of epithelial shape transitions during animal development [0.03%]
动物发育过程中上皮形状转换的多尺度生物物理调控
Jianyi Mai,Abhirami Anil Gayathry,David M Richards et al.
Jianyi Mai et al.
The regulation of epithelial cell shape is fundamental to development, homeostasis and disease, and is intricately linked to tissue function. Epithelial morphology emerges from integration of biochemical and mechanical cues across multiple ...
Si Li,Xiang Shi,Xue-Lian Sun et al.
Si Li et al.
Adult neural stem cells (NSCs) persist throughout life in discrete neurogenic niches of the mammalian brain, most prominently the subventricular zone (SVZ), the subgranular zone (SGZ) of the hippocampal dentate gyrus, and the hypothalamic v...
Lei Xia,Anish Ashok Adpaikar,Liling Wen et al.
Lei Xia et al.
Tissue development and regeneration are governed by a dynamic interplay between biochemical signaling programs and biophysical forces that act across molecular, cellular, and tissue scales. Mechanical cues including cytoskeletal tension, ex...
Cilia and flagella - Current insights from diverse experimental systems [0.03%]
纤毛和鞭毛——来自多种实验体系的最新认识
Junmin Pan
Junmin Pan
Editorial for special issue "When should mathematical models be used in biology" [0.03%]
特刊 “在生物学中何时应使用数学模型”的主编评论
Wallace F Marshall
Wallace F Marshall
Conserved machinery, divergent functions: evolutionary plasticity of the STK36/ULK4 kinase complex in ciliogenesis and signaling [0.03%]
保守的机械装置，发散的功能：STK36 / ULK4激酶复合物在纤毛发生和信号传导中的进化塑性
Bowen Wan,Ngai Yin Brad Leung,Mu He
Bowen Wan
The cilium is an ancient organelle in eukaryotes essential for motility, sensory perception, and signaling, and ciliary dysfunction underlies a spectrum of human ciliopathies. In this context, the STK36/ULK4 kinase complex has emerged as a ...
Mingming Zhang,Shuo Han
Mingming Zhang
Understanding the spatiotemporal dynamics of molecular and cellular processes is central to unraveling the mechanisms of development, tissue regeneration, and aging. Chemical biology provides a unique and powerful toolkit to meet this chall...
Siddhartha Chakraborty,Khanh Huy Bui
Siddhartha Chakraborty
Cilia are evolutionarily conserved organelles essential for motility and signaling, and their dysfunction underlies a wide spectrum of human diseases. The ciliate Tetrahymena is a powerful model organism for dissecting ciliary biology due t...
Arica Beisaw,Felix Gunawan
Arica Beisaw
Endothelial origin of hematopoietic stem cells: Insights from new technologies and unresolved questions [0.03%]
造血干细胞的血管内皮起源：新技术带来的启示与未决问题
Xiaochen Ding,Gaoke Liu,Bing Liu et al.
Xiaochen Ding et al.
Recent studies employing advanced technologies have supported the notion that definitive hematopoiesis, including the generation of hematopoietic stem cells (HSCs), originates from hemogenic endothelial cells (HECs). However, controversies ...