Emily N Kukan,Gabrielle L Fabiano,Brian A Cobb
Emily N Kukan
The sialic acid-binding immunoglobulin-like lectins (Siglecs) are a family of receptors expressed widely on cells of the hematopoietic system. Siglecs recognize terminal sialic acid residues on glycans and often initiate intracellular signa...
Bali Pulendran
Bali Pulendran
The origins, manifestations, and potential treatments of allergic disorders [0.03%]
过敏性疾病的起源、表现及潜在治疗方法
Donata Vercelli,Stephen J Galli
Donata Vercelli
Durability of immune responses to SARS-CoV-2 infection and vaccination [0.03%]
针对SARS-CoV-2感染和疫苗接种的免疫反应持久性
Mehul S Suthar
Mehul S Suthar
Infection with SARS-CoV-2 in humans has caused a pandemic of unprecedented dimensions. SARS-CoV-2 is primarily transmitted through respiratory droplets and targets ciliated epithelial cells in the nasal cavity, trachea, and lungs by utilizi...
Early life microbiome influences on development of the mucosal innate immune system [0.03%]
生命早期微生物组对黏膜先天免疫系统发育的影响
Aline Ignacio,Sonia Czyz,Kathy D McCoy
Aline Ignacio
The gut microbiota is well known to possess immunomodulatory capacities, influencing a multitude of cellular signalling pathways to maintain host homeostasis. Although the formation of the immune system initiates before birth in a sterile e...
Feng Shao
Feng Shao
B cell clonality in cancer [0.03%]
癌症中的B细胞克隆性
E A Bryushkova,N V Mushenkova,M A Turchaninova et al.
E A Bryushkova et al.
Carcinogenesis in the process of long-term co-evolution of tumor cells and immune environment essentially becomes possible due to incorrect decisions made, remembered, and reproduced by the immune system at the level of clonal populations o...
Matthew C Woodruff,Caterina E Faliti,Ignacio Sanz
Matthew C Woodruff
The integration of multi-'omic datasets into complex systems-wide assessments has become a mainstay in immunologic investigation. This focus on high-dimensional data collection and analysis was on full display in the investigation of COVID-...
Michael J Peluso,Mohamed Abdel-Mohsen,Timothy J Henrich et al.
Michael J Peluso et al.
Since the onset of the COVID-19 pandemic, significant progress has been made in developing effective preventive and therapeutic strategies against severe acute SARS-CoV-2 infection. However, the management of Long COVID (LC), an infection-a...
Jose R Conejo-Garcia,Paulo C Rodriguez
Jose R Conejo-Garcia