Kiranmye Reddy,Jonathan D Fish,Jennifer Eng et al.
Kiranmye Reddy et al.
Purpose: To assess the prevalence and severity of transfusion-associated iron overload (IO) in childhood cancer survivors (CCS). Patients and methods: ...
Relationship between PCT, CRP, and IL-6 and postoperative delirium in ICU patients and its influencing factors [0.03%]
ICU患者术后谵妄与PCT、CRP和IL-6的关系及其影响因素
Huayong Song,Lijing Shen,Wen Sun et al.
Huayong Song et al.
Objective: To investigate the relationship of procalcitonin (PCT), C-reactive protein (CRP), and interleukin-6 (IL-6) with postoperative delirium (POD) in intensive care unit (ICU) patients, and to identify influencing fa...
Ex vivo culture of hematopoietic stem and progenitor cells with platelet lysate: Investigating proliferation and erythroid-megakaryocytic lineage effects [0.03%]
含血小板 lysate 的体外造血干细胞和祖细胞培养：探究其增殖及红系-巨核系分化的影响
Farnaz Pirsavabi,Zahra Najafi,Mohammad Ebrahimi Siahboomi et al.
Farnaz Pirsavabi et al.
Hematopoietic stem and progenitor cells (HSPCs) are valuable for therapies and research due to their self-renewal and differentiation abilities. The ex vivo culture of these cells necessitates conditions that maintain their unique propertie...
Brian D Chen,Amanda Tapia,Eric Boerwinkle et al.
Brian D Chen et al.
Complete blood counts (CBCs) are commonly measured in clinical practice and are associated with different diseases and traits. Statistical adjustment for blood cell abundance or related traits in these metabolomic epidemiology studies is no...
Oxidantscan: A novel biomarker to assess red blood cell susceptibility to oxidative stress in sickle cell disease [0.03%]
新型生物标志物氧化剂扫描：评估镰状细胞病患者红血细胞氧化应激敏感性
C A Hernández,M J M Traets,W W van Solinge et al.
C A Hernández et al.
Red blood cells (RBC) from patients with sickle cell disease (SCD) are continuously exposed to high levels of oxidative stress, which impacts RBC deformability. In this study, we applied a novel technique (oxidantscan) to measure deformabil...
Effects of G-CSF and 5-FU as conditioning regimens in platelet-targeted gene therapy for hemophilia B [0.03%]
G-CSF和5-FU作为造血干细胞移植预处理方案在板层素靶向基因治疗乙型血友病中的作用研究
Wenjue Xu,Huiyan Han,Binbin Li et al.
Wenjue Xu et al.
Platelet-targeted gene therapy for hemophilia entails modifying a patient's hematopoietic stem cells (HSCs) ex vivo to produce platelets containing coagulation factors, offering a potential cure by localized factor release at injury sites. ...
Anti-sickling efficacy and safety of Sailin-HbS, an indigenous Ayurvedic formulation [0.03%]
防治镰状细胞病的印度传统药物Sailin-HbS及其安全性研究
Shruti Bhatt,Anil Bhansali,Apratim Sai Rajesh et al.
Shruti Bhatt et al.
Sickle Cell Disease (SCD) is a hereditary condition characterized by a mutation in globin chains of hemoglobin. Polymerization of deoxygenated sickle hemoglobin (HbS) leads to rigid sickle shaped red blood cells (RBC), the primary cause of ...
WGCNA and LASSO regression-based selection and validation of microRNA biomarkers of β-thalassemia [0.03%]
基于WGCNA和LASSO回归的微小核糖核酸β型地中海贫血生物标志物的选择与验证
Fang Yang,Ling Shi,Sha Su et al.
Fang Yang et al.
Objective: In patients with severe β-thalassemia, fetal hemoglobin (HbF) upregulation may provide an avenue to better therapeutic outcomes. The mechanisms that regulate the expression of HbF, however, are currently uncle...
A case series of cerebrovascular abnormalities in Townes sickle cell mice visualized with magnetic resonance imaging and angiography [0.03%]
磁共振成像和血管造影下观察到的多只托恩斯镰状细胞病鼠的大脑血管异常案例系列分析
Liana Hatoum,Hannah Song Lee,John N Oshinski et al.
Liana Hatoum et al.
Arterial complications in sickle cell disease (SCD), including stenoses and occlusions, are critical contributors to stroke. Townes SCD mice exhibit neurocognitive deficits and micro-vasculopathy, however stenoses and occlusions that could ...
AI for patient education: Insights from DeepSeek's responses on megaloblastic anemia [0.03%]
用于患者教育的人工智能：来自DeepSeek的巨幼细胞性贫血回复分析给我们的启示
Nidhi Chandrashekar Patil
Nidhi Chandrashekar Patil