Blood Board: A virtual community of practice for classical hematology education and care improvement [0.03%]
血板：古典血液学教育和护理改善的虚拟实践社区
Richard C Godby,Jennifer Gile,Xavier Andrade-Gonzalez et al.
Richard C Godby et al.
Enhancing access to sickle cell disease diagnosis in Africa using the gazelle® portable digital microchip electrophoresis platform [0.03%]
在非洲使用Gazelle便携式数字微芯片电泳平台增强镰状细胞病诊断的可及性
Arwa Fraiwan,Bernard E Ebruke,Abubakar Gezawa et al.
Arwa Fraiwan et al.
Sickle Cell Disease (SCD), a genetic blood disorder, claims the lives of thousands of young children in Africa every year. The World Health Organization estimates that 75% of the diagnosed cases of the disease are within sub-Saharan Africa ...
Albumin fusion of the rVWF fragment rD'D3 reduces internalisation by clearance receptor Stabilin-2 [0.03%]
融合白蛋白减少rVWF片段rD'D3的内吞作用及其与清除受体Stabilin-2的相互作用
Kim G Lieu,Sabine Pestel,Mhairi Maxwell et al.
Kim G Lieu et al.
A recombinant VWF D'D3 albumin fusion protein (rD'D3-FP) has been developed to extend the half-life of co-administered coagulation factor VIII (FVIII) for the treatment of haemophilia A. We examined the impact of albumin fusion of rD'D3 on ...
Managing heavy menstrual bleeding in adolescents with bleeding disorders: Outcomes from a pragmatic LMIC approach [0.03%]
发展中地区实用方法管理青少年出血性疾病患者的重度月经过多结局分析
Sandhya Gupta,Nita Radhakrishnan,Archit Pandharipande et al.
Sandhya Gupta et al.
Background: Heavy menstrual bleeding (HMB) a common manifestation of bleeding disorders in adolescents contributes to anemia, transfusions, and impaired quality-of-life (QOL). Evidence supporting practical management stra...
HbS-β thalassemia mimicking HbSS on DdeI RFLP: Report of a pitfall circumventable by Sanger sequencing and parental testing [0.03%]
HbS-β地中海贫血的DdeI酶切片段多态性（RFLP）分析结果类似HbSS：采用Sanger测序和父母检查可避免误判报告一例
Diksha Dev Yadav,Jasbir Kaur Hira,Sanjeev Chhabra et al.
Diksha Dev Yadav et al.
MRI-derived hepatic fat and its clinical correlates in non-transfusion-dependent thalassemia: a cross-sectional study [0.03%]
非输血依赖性地中海贫血患者肝脏脂肪磁共振值及其临床相关因素：横断面研究
Antonella Meloni,Laura Pistoia,Paolo Ricchi et al.
Antonella Meloni et al.
We quantified hepatic fat fraction (FF) by magnetic resonance imaging (MRI) in non-transfusion-dependent thalassemia (NTDT) patients, and we evaluated its associations with demographic, clinical, and biochemical parameters, tissue iron over...
Inflammatory markers in sickle cell disease during vaso-occlusive crisis [0.03%]
镰状细胞病急性血管阻塞危象期的炎症标志物变化
Kamal Kumar Meher,Pradeep Kumar Mohanty,Satyabrata Meher
Kamal Kumar Meher
Sickle cell disease (SCD) is a monogenic blood disorder in which vaso-occlusive crises (VOC) are the main cause of hospitalization. Along with vascular adhesion, inflammation plays a central role in VOC. This study compared inflammatory and...
Newborn screening for sickle cell disease in Angola: Implementation challenges and emerging data on hemoglobinopathy prevalence [0.03%]
安哥拉镰状细胞病新生儿筛查的实施挑战及血红蛋白病患病率的数据公布
Miguel Brito,Catarina Ginete,Mariana Jacinto et al.
Miguel Brito et al.
Sickle Cell Disease (SCD) is an autosomal recessive disorder with a substantial global burden. Despite its particularly high incidence in sub-Saharan Africa, early diagnosis remains limited in many countries. The objective of this study was...
Exercise training adaptations on cardiorespiratory fitness and quality of life of patients with sickle cell disease: A systematic review [0.03%]
锻炼训练对镰状细胞病患者心肺功能和生活质量影响的系统评价
Gilson Dorneles,Igor da Silva,Bruna Marmett
Gilson Dorneles
This study aims to assess the effect of endurance training on cardiorespiratory adaptations and health-related quality of life (HRQoL) of patients with sickle cell disease (SCD). Three databases (Pubmed, Embase and Web of Science) were sear...
Clinical outcomes and health-system challenges in congenital afibrinogenemia: a single-centre prospective case series [0.03%]
先天性无纤维蛋白原血症的临床转归和卫生系统挑战：一项单中心前瞻性病例系列研究
Nita Radhakrishnan,Savitri Singh,Archit Pandharipande et al.
Nita Radhakrishnan et al.
Background: Congenital afibrinogenemia is a very rare bleeding disorder which is often life threatening. Data are scarce, and only 29 Indian cases have been officially reported to World Federation of Hemophilia, mostly as...