Thirty-five males with severe (Class 1) G6PD deficiency (c.637G>T) in a North American family of European ancestry [0.03%]
欧洲血统的北美家族中35名具有严重(G6PD c.637G>T)缺陷的男性成员分析
Timothy M Bahr,Archana M Agarwal,Jessica A Meznarich et al.
Timothy M Bahr et al.
In North America, jaundiced neonates are not usually tested for G6PD deficiency if the family is of European ancestry. However, we describe such a family where ≥35 males have had severe (Class I) G6PD deficiency. Many of the jaundiced neon...
Trpv1 and Trpa1 are not essential for Psickle-like activity in red cells of the SAD mouse model of sickle cell disease [0.03%]
在SAD鼠模型中的红细胞内，Trpv1和Trpa1不是Psickle样活性的必需因素
David H Vandorpe,Alicia Rivera,Boris E Shmukler et al.
David H Vandorpe et al.
The molecular identity of Psickle, the deoxygenation-activated cation conductance of the human sickle erythrocyte, remains unknown. We observed in human sickle red cells that inhibitors of TRPA1 and TRPV1 inhibited Psickle, whereas a TRPV1 ...
Malignant histiocytosis with a Langerhans cell subtype: A report on the diagnostic and therapeutic challenge [0.03%]
朗格汉斯细胞型恶性组织细胞增多症：诊断与治疗难题报道
Amel Kime,Claire Bréal,Anne-Ségolène Cottereau et al.
Amel Kime et al.
Analysis of evolutionary conservation of GPI-anchored proteins between humans and mice [0.03%]
人类和小鼠之间GPI锚定蛋白的演化保守性分析
Sushant Kumar,Daria V Babushok
Sushant Kumar
Eltrombopag as second line treatment in patients with primary immune thrombocytopenia: A single center real life experience [0.03%]
原发免疫性血小板减少症患者的二线治疗药物艾曲波帕：单中心真实世界经验
Angelo Gardellini,Francesca Guidotti,Maddalena Feltri et al.
Angelo Gardellini et al.
Glucocorticoid treatment is the standard initial therapy for patients with immune thrombocytopenia (ITP). Despite a rate of 60-80% of initial remissions, only 30 to 50% of adults have a sustained response after discontinuation. Second line ...
Observational Study
Blood cells, molecules & diseases. 2021 Dec:92:102620. DOI:10.1016/j.bcmd.2021.102620 2021
Marshall A Lichtman
Marshall A Lichtman
Zachary Weber,Ashley Sam,Alejandra Pena et al.
Zachary Weber et al.
Abnormally high serum ferritin levels have been reported during pediatric ECMO, attributed to frequent red blood cell transfusion and suggestive of iron overload. However, the utility of ferritin for diagnosing iron overload is complicated ...
Observational Study
Blood cells, molecules & diseases. 2021 Dec:92:102617. DOI:10.1016/j.bcmd.2021.102617 2021
Severe immune thrombocytopenia after COVID-19 vaccination: Report of four cases and review of the literature [0.03%]
COVID-19疫苗接种后出现严重免疫性血小板减少症：四例病例报告及文献回顾
Angelo Gardellini,Francesca Guidotti,Elena Maino et al.
Angelo Gardellini et al.
Isolated central nervous system relapse of acute promyelocytic leukemia with altered morphology in an asymptomatic patient [0.03%]
无症状患者急性早幼粒细胞白血病孤立中枢神经系统复发并形态学改变
Ruhani Sardana,Jayalakshmi P Balakrishna
Ruhani Sardana
Global geographic differences in healthcare utilization for sickle cell disease pain crises in the CASiRe cohort [0.03%]
CASiRe队列中镰状细胞疾病疼痛危象的全球地域医疗利用差异
Crawford Strunk,Immacolata Tartaglione,Connie M Piccone et al.
Crawford Strunk et al.
Background: Sickle cell disease (SCD) is characterized by frequent, unpredictable pain episodes and other vaso-occlusive crises (VOCs) leading to significant healthcare utilization. VOC frequency is often an endpoint in c...