Unveiling mortality risk factors in paediatric sickle cell disease patients during acute crises in the Democratic Republic of the Congo [0.03%]
在刚果民主共和国小儿缺血病患者急性危象期间揭示死亡风险因素
Paul Muteb Boma,Stéphanie Luntadila Ngimbi,Junior Makiese Kindundu et al.
Paul Muteb Boma et al.
Sickle cell disease (SCD) is a significant health burden in the Democratic Republic of the Congo (DRC). This study aims to identify predictive factors of mortality in SCD children admitted to emergency care in Lubumbashi, DRC. We performed ...
Effect of voxelotor on murine bone marrow and peripheral blood with hematopoietic progenitor cell mobilization for gene therapy of sickle cell disease [0.03%]
voxelotor对造血祖细胞动员的小鼠骨髓和外周血的影响基因治疗方案用于治疗镰状细胞疾病
Avital Mendelson,Yunfeng Liu,Weili Bao et al.
Avital Mendelson et al.
In preparation for hematopoietic stem cell mobilization and collection, current ex vivo gene therapy protocols for sickle cell disease require patients to undergo several months of chronic red cell transfusion. For health care equity, alter...
Regarding γ' fibrinogen levels as a biomarker of COVID-19 respiratory disease severity [0.03%]
关于将γ'纤维蛋白原水平作为COVID-19呼吸道疾病严重程度的生物标志物的问题
Sangsang Wang,Diao Yu,Junwu Zhang
Sangsang Wang
Bio-net dataset: AI-based diagnostic solutions using peripheral blood smear images [0.03%]
生物网络数据集：使用周边血涂片图像的AI基础诊断方案
Usman Ali Shams,Isma Javed,Muhammad Fizan et al.
Usman Ali Shams et al.
Peripheral blood smear examination is one of the basic steps in the evaluation of different blood cells. It is a confirmatory step after an automated complete blood count analysis. Manual microscopy is time-consuming and requires profession...
Unmasking the morphological alteration of erythrocytes among women suffering from PCOS [0.03%]
揭开患有PCOS的女性红细胞形态改变的面纱
Sutithi Dey,Ipsita Chakraborty,Payel Biswas et al.
Sutithi Dey et al.
Dyslipidemia is frequently observed in polycystic ovarian syndrome (PCOS). Changes in plasma lipid levels potentially alter erythrocyte membrane lipid composition due to lack of inbuilt lipid synthesis machinery. Therefore, development of m...
Characterization of a cohort of Angolan children with sickle cell anemia treated with hydroxyurea [0.03%]
接受羟基脲治疗的安哥拉患镰状细胞贫血症儿童群体的特征分析
Brígida Santos,Catarina Ginete,Elisângela Gonçalves et al.
Brígida Santos et al.
Background: Sickle Cell Anemia (SCA) is a monogenic disease, although its severity and response to treatment are very heterogeneous. Objectives: ...
Impact of CD34 positive cell dose in donor graft on the outcomes after haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide - A retrospective single-center study with a Japanese cohort [0.03%]
供者移植物中CD34阳性细胞剂量对移植后环磷酰胺联合单倍体外周血干细胞移植预后的影响-一项包含日本患者队列的单中心回顾性研究
Yumiko Maruyama,Hidekazu Nishikii,Naoki Kurita et al.
Yumiko Maruyama et al.
Background: Haploidentical peripheral blood stem cell transplantation (haplo-PBSCT) with post-transplant cyclophosphamide (PTCy) is an important therapeutic option for patients lacking an HLA-matched donor. However, the s...
Measurement of red cell, plasma and blood volume: Essential components of diagnostic and research studies of oxygen transport [0.03%]
红细胞、血浆和全血容量的测定：氧运输诊断和研究的重要组成部分
Marshall A Lichtman,Josef T Prchal
Marshall A Lichtman
Calcium flux alterations in erythrocytes from sickle cell mice: The relevance of mean corpuscular volume [0.03%]
异常血红蛋白小鼠红细胞钙稳态的变化:平均红细胞体积的意义
Luis E F Almeida,Meghann L Smith,Sayuri Kamimura et al.
Luis E F Almeida et al.
Red blood cells (RBC) from patients with sickle cell disease (SCD) have elevated calcium levels at baseline, which are further elevated upon deoxygenation. Here we examined baseline calcium levels and calcium flux in RBCs from a mouse model...
Clonal hematopoiesis and acquired genetic abnormalities of the red cell: An historical review [0.03%]
克隆性血液生成和获得性的红细胞遗传异常：历史回顾
Marshall A Lichtman
Marshall A Lichtman
Several syndromes affecting the red cell that mimic those induced by germline mutations may result from a somatic mutation that accompanies a myeloid malignancy. These syndromes are most notable in cases of myelodysplastic syndrome, but the...