Nuclear staining of fgfr-2/stat-5 and runx-2 in mucinous breast cancer [0.03%]
黏液乳腺癌FGFR-2/STAT-5和RUNX-2的核染色
María May,Julián Mosto,Paula Martinez Vazquez et al.
María May et al.
Mucinous carcinoma (MBC) is a rare subtype of breast cancer characterized by the production of variable amounts of mucin, with a prognosis better than that of non-mucinous carcinomas (NMBC). The aim of this project was to evaluate the expre...
Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases [0.03%]
基于扩增子的下一代测序在小细胞肺癌转移灶诊断中的应用
Lydia Meder,Katharina König,Jana Fassunke et al.
Lydia Meder et al.
Small cell lung carcinoma (SCLC) is the most aggressive entity of lung cancer. Rapid cancer progression and early formation of systemic metastases drive the deadly outcome of SCLC. Recent advances in identifying oncogenes by cancer whole ge...
The association of HPV genotype with the regression, persistence or progression of low-grade squamous intraepithelial lesions [0.03%]
人乳头瘤病毒分型与低度鳞状上皮内病变消退、持续或进展的相关性分析
F A Silveira,G Almeida,Y L Furtado et al.
F A Silveira et al.
Background: Human papillomavirus (HPV) is a highly prevalent sexually transmitted virus causing cytological alterations that precede cervical cancer. Approximately 130 genotypes have been sequenced. Low-grade squamous int...
CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway [0.03%]
CARMA3通过激活NF-κB和抑制P38 MAPK信号通路调控非小细胞肺癌细胞的浸润、迁移及凋亡
Z X Xia,Z X Li,M Zhang et al.
Z X Xia et al.
In our previous study, CARMA3 overexpression in lung cancer cells promoted cell proliferation and invasion; however, the mechanism underlying the role of CARMA3 in cancer cell invasion remained unclear. In the present study, knockdown of CA...
GATA6 is overexpressed in breast cancer and promotes breast cancer cell epithelial-mesenchymal transition by upregulating slug expression [0.03%]
GATA6在乳腺癌中过表达并通过上调slug促进上皮间质转化
Yongchun Song,Tao Tian,Xiao Fu et al.
Yongchun Song et al.
Metastasis is the leading cause of death in breast cancer (BC) patients. However, until now, the mechanisms of BC metastasis remain elusive. GATA6 is a member of the GATA transcription factor family that plays critical regulatory roles in t...
Differentially expressed microRNAs in kidney biopsies from various subtypes of nephrotic children [0.03%]
儿童不同类型的肾病综合征活检标本中差异表达的微小核糖核酸分子谱的研究
Meiling Lu,Cheng Wang,Yunlong Yuan et al.
Meiling Lu et al.
Background: Our previous study showed a set of increased miRNAs in serum or urine from nephrotic syndrome children. In this study, we investigated the renal expression of these miRNAs in nephrotic children and explored th...
PCR-sequencing is a complementary method to amplification refractory mutation system for EGFR gene mutation analysis in FFPE samples [0.03%]
聚合酶链反应测序是福马酸固定石蜡包埋肺癌组织标本表皮生长因子受体基因突变分析的一种补充方法：与等位基因特异性PCR技术比较研究
Junchang Jiang,Chunhua Wang,Xiaoli Yu et al.
Junchang Jiang et al.
Amplification Refractory Mutation System (ARMS) is the most popular technology for EGFR gene mutation analysis in China. Cutoff Ct or ΔCt values were used to differentiate low mutation abundance cases from no mutation cases. In this study,...
C5a receptor enhances hepatocellular carcinoma cell invasiveness via activating ERK1/2-mediated epithelial-mesenchymal transition [0.03%]
C5a受体通过激活ERK1 / 2介导的上皮间质转化增强肝癌细胞侵袭性
Wen-Hao Hu,Zhe Hu,Xian Shen et al.
Wen-Hao Hu et al.
C5a and its receptor, C5a receptor (C5aR), play critical roles in tumor progression. However, mechanisms of C5a-C5aR axis in hepatocellular carcinoma (HCC) cell invasiveness are not fully elucidated. In this study, we found that C5aR expres...
A simple procedure for the extraction of DNA from long-term formalin-preserved brain tissues for the detection of EBV by PCR [0.03%]
一种简单的从长期福尔马林固定的脑组织中提取DNA用于PCR检测EBV的方法
Asma Hassani,Gulfaraz Khan
Asma Hassani
Long-term formalin fixed brain tissues are potentially an important source of material for molecular studies. Ironically, very few protocols have been published describing DNA extraction from such material for use in PCR analysis. In our at...
Fei Ye,Nicholas Chan,Tao Feng et al.
Fei Ye et al.
Background: Cervical cancer is the second most common form of cancer among women. There are over 100 different types of human papillomavirus (HPV), 40 of which are frequently detected in anogenital mucosa. HPV is the prim...