Neutrophil extracellular traps induced by a monoclonal anti-phosphatidylserine/prothrombin antibody activate platelets in vitro [0.03%]
一种抗磷脂抗体通过诱导中性粒细胞胞外诱捕网活化血小板
Suishin Arai,Koki Takai,Hiyori Miyatake et al.
Suishin Arai et al.
Antiphospholipid syndrome (APS) is an autoimmune thrombotic disorder characterized by the presence of antiphospholipid antibodies, including anti-phosphatidylserine/prothrombin antibodies (aPS/PT). While neutrophil extracellular traps (NETs...
Hidden proteins encoded by non-canonical open reading frames: A review [0.03%]
非 canonical 开读框编码的隐藏蛋白:综述
Jiang-Xue Li,Yan-Xia Qin,Zhao Li et al.
Jiang-Xue Li et al.
There is increasing evidence that translation is not limited to annotated protein-coding genes. Ribosome profiling sequencing, mass spectrometry-based proteomics, and immunopeptidomics have identified the productive translation of non-canon...
Automated imaging workflow for FISH-stained tissue microarrays enables assessment of FGFR2 translocations in a large intrahepatic cholangiocarcinoma patient cohort [0.03%]
用于FISH染色组织微阵列的自动化成像工作流程可评估大样本肝内胆管癌患者的FGFR2易位
Isis Lozzi,Jan Schmoranzer,Alexander Arnold et al.
Isis Lozzi et al.
Background: Fibroblast growth factor receptor-2 (FGFR2) translocations are frequently observed in intrahepatic cholangiocarcinoma (iCCA) and represent actionable therapeutic targets. While fluorescence in situ hybridizati...
Charged to death: Energy drinks, smart drugs, and sudden cardiac death [0.03%]
充电至死:能量饮料、聪明药及突发性心脏死亡事件
Francesco Sessa,Federica Ministeri,Mario Chisari et al.
Francesco Sessa et al.
Sudden cardiac death (SCD) in individuals ≤35 years remains a major challenge for cardiology and forensic medicine, often affecting subjects without prior symptoms. At the same time, the consumption of energy drinks (EDs) and the medical o...
Intratumoral collagen correlates with histological grade and patient prognosis in breast cancer [0.03%]
乳腺癌中肿瘤内的胶原与组织学分级及患者预后相关
Chaido Sirinian,Fabio Marchianò,Elpida Kenanidou et al.
Chaido Sirinian et al.
Histological grading, using the Nottingham Grading System (NGS), is a major prognostic indicator for breast cancer. NGS involves the scoring of cancer cell-related morphological features, yet it overlooks tumor microenvironment (TME) compon...
METTL13 at the interface of translational control, protein methylation, and disease biology [0.03%]
METTL13在翻译控制、蛋白质甲基化和疾病生物学的交汇点上的作用
Jiejie He,Yongli Yang,Yan Li
Jiejie He
Methyltransferase-like 13 (METTL13) is a member of the methyltransferase-like (METTL) family characterized by two conserved seven-beta-strand(7BS) catalytic domains. Current evidence identifies METTL13 primarily as a dual protein methyltran...
Biomarkers for congestion assessment and prognosis in acute heart failure: A systematic review [0.03%]
急性心力衰竭患者充血评估与预后生物标志物的系统评价
Andreea Asaftei,Alexandr Ceasovschih,Mihai Constantin et al.
Andreea Asaftei et al.
Congestion is the central pathophysiological mechanism and a major determinant of morbidity and mortality in acute heart failure (AHF). Natriuretic peptides (NPs), although guideline-recommended, provide only an indirect assessment of conge...
NanoString nCounter® analysis of tissue microarray punch samples from colorectal carcinomas with invasive margins of the expansive and infiltrative type [0.03%]
NanoString nCounter® 富集性和浸润性结直肠癌肿瘤边缘组织微阵列样本的分析
Maja Hühns,Caterina Redwanz,Friedrich Prall
Maja Hühns
By a classical approach, the invasive margins of colorectal carcinomas can be typed as expansive or infiltrative, the latter portending a poor prognosis. To gain insight into the tumor biology behind these morphological features, we submitt...
Bacteriological profile of secondary infections following snakebite envenomation's: A systematic literature review [0.03%]
毒蛇咬伤后继发感染的细菌谱系:系统文献综述
Marcos Gabriel Maciel Salazar,Amanda Maria Picelli,Victor Carlos Pardo Ratis da Silva et al.
Marcos Gabriel Maciel Salazar et al.
Introduction: Secondary infection is a significant complication of snakebite envenomation, with considerable impact on clinical outcomes. Identifying the bacterial agents involved is essential for appropriate case managem...
3D virtual histopathology of human breast tissues using an X-ray grating interferometry micro CT system [0.03%]
采用X射线光栅干涉微CT系统的人体乳腺组织三维虚拟病理学研究
Alexandre Pereira,Stefanie Kaser,Zsuzsanna Varga et al.
Alexandre Pereira et al.
Breast cancer remains the most prevalent malignancy among women worldwide. When suspicious lesions are detected, standard clinical workflows rely on histopathological evaluation of excised tissue (biopsy) and the choice of preoperative syst...