Complement-fixing antibodies against denatured HLA and MICA antigens are associated with antibody mediated rejection [0.03%]
针对变性HLA和MICA抗原的补体结合抗体与抗体介导的排斥反应有关
Junchao Cai,Paul I Terasaki,Dong Zhu et al.
Junchao Cai et al.
Background: We have found antibodies against denatured HLA class I antigens in the serum of allograft recipients which were not significantly associated with graft failure. It is unknown whether transplant recipients also...
Plasmablastic lymphoma presenting as a large intracardiac mass and bilateral pleural effusions [0.03%]
表现为巨大心腔内肿物和双侧胸腔积液的浆细胞样淋巴瘤病例报告
Xin Qing,Elena Enbom,Annie Qing et al.
Xin Qing et al.
Plasmablastic lymphoma (PBL) is a rare aggressive lymphoma arising most frequently in the oral cavity of HIV-infected patients. Rare cases of PBL have been reported in extra-oral sites, as well as in HIV-negative patients. Cardiac involveme...
PGRN promotes migration and invasion of epithelial ovarian cancer cells through an epithelial mesenchymal transition program and the activation of cancer associated fibroblasts [0.03%]
PGRN通过上皮间质转化程序和激活癌相关成纤维细胞促进卵巢癌细胞迁移和侵袭
Taotao Dong,Dong Yang,Rui Li et al.
Taotao Dong et al.
In this paper, we aimed to explore whether progranulin (PGRN) could induce epithelial ovarian cancer cells to undergo an epithelial mesenchymal transition (EMT) program directly and through its activation of cancer associated fibroblasts (C...
Targeting the expression of glutathione- and sulfate-dependent detoxification enzymes in HepG2 cells by oxygen in minimal and amino acid enriched medium [0.03%]
最少和氨基酸富集培养基中的氧气对肝癌HepG2细胞中谷胱甘肽及硫酸依赖型解毒酶表达的影响
Ewa Usarek,Wojciech Graboń,Beata Kaźmierczak et al.
Ewa Usarek et al.
Cancer cells exhibit specific metabolism allowing them to survive and proliferate in various oxygen conditions and nutrients' availability. Hepatocytes are highly active metabolically and thus very sensitive to hypoxia. The purpose of the s...
Annerose Berndt,Cheryl Ackert-Bicknell,Kathleen A Silva et al.
Annerose Berndt et al.
Fibro-osseous lesions in mice are progressive aging changes in which the bone marrow is replaced to various degrees by fibrovascular stroma and bony trabeculae in a wide variety of bones. The frequency and severity varied greatly among 28 d...
Association of mitochondrial mutations with the age of patients having atherosclerotic lesions [0.03%]
线粒体基因突变与动脉粥样硬化患者的年龄之间的关系研究
Margarita A Sazonova,Vasily V Sinyov,Valeria A Barinova et al.
Margarita A Sazonova et al.
Mitochondrial genome mutations are associated with different pathologies. Earlier the authors of the study found an association of some mitochondrial genome mutations with atherosclerosis. In the present study, an attempt to analyze a conne...
Glutaminases in slowly proliferating gastroenteropancreatic neuroendocrine neoplasms/tumors (GEP-NETs): Selective overexpression of mRNA coding for the KGA isoform [0.03%]
胃肠道胰神经内分泌肿瘤(GEP-NETs)中的谷氨酰胺酶：KGA同工异构体的mRNA选择性过表达
Monika Szeliga,Jarosław Ćwikła,Marta Obara-Michlewska et al.
Monika Szeliga et al.
Glutamine (Gln) is a crucial metabolite in cancer cells of different origin, and the expression and activity of different isoforms of the Gln-degrading enzyme, glutaminase (GA), have variable implications for tumor growth and metabolism. Hu...
A study of the expression and localization of toll-like receptors 2 and 9 in different grades of cervical intraepithelial neoplasia and squamous cell carcinoma [0.03%]
宫颈鳞状细胞癌和不同级别的宫颈上皮内瘤变中TLR2、TLR9的表达及定位研究
Arnab Ghosh,Anindya Dasgupta,Arghya Bandyopadhyay et al.
Arnab Ghosh et al.
TLRs are important molecules of innate immune response, those play central role in host pathogen interaction and recognition through pathogen associated molecular patterns (PAMPs). Previous studies have indicated the role of TLRs in many hu...
Effects of Il-33/St2 pathway on alteration of iron and hematological parameters in acute inflammation [0.03%]
IL-33/ST2信号通路在急性炎症中铁和血液学参数改变中的作用研究
Marija S Stankovic,Vladimir Turuntas,Silvio R De Luka et al.
Marija S Stankovic et al.
Aim: The aim of this study was to examine the role of the IL-33/ST2 pathway in pathogenesis of acute inflammation by investigating its possible role in alteration of iron and hematological parameters in experimental model...
Cardiac stem cells transplantation enhances the expression of connexin 43 via the ANG II/AT1R/TGF-beta1 signaling pathway in a rat model of myocardial infarction [0.03%]
心脏干细胞移植通过ANG II/AT1R/TGF-β1信号途径增强心梗大鼠模型中缝隙连接蛋白43的表达
Jingying Hou,Ping Yan,Tianzhu Guo et al.
Jingying Hou et al.
Background: In this study, we hypothesized that CSCs mediated the expression of Cx43 after transplantation post MI via the ANG II/AT1R/TGF-beta1 signaling pathway. ...