Promoter methylation of APC and RAR-β genes as prognostic markers in non-small cell lung cancer (NSCLC) [0.03%]
APC和RAR-β基因启动子甲基化在非小细胞肺癌中的预后标志物价值研究
Hongxiang Feng,Zhenrong Zhang,Xin Qing et al.
Hongxiang Feng et al.
Aberrant promoter hypermethylations of tumor suppressor genes are promising markers for lung cancer diagnosis and prognosis. The purpose of this study was to determine methylation status at APC and RAR-β promoters in primary NSCLC, and whe...
Co-expression of vascular and lymphatic endothelial cell markers on early endothelial cells present in aspirated coronary thrombi from patients with ST-elevation myocardial infarction [0.03%]
急性ST段抬高性心肌梗死患者冠状动脉抽吸血栓中早期内皮细胞血管和淋巴内皮标记共表达的现象
Jelena Rakocevic,Snezana Kojic,Dejan Orlic et al.
Jelena Rakocevic et al.
Introduction: Angiogenesis is the growth of both new vascular and lymphatic blood vessels from the existing vasculature. During this process, blood endothelial cells (BECs) and lymphatic endothelial cells (LECs) express s...
Early adventitial activation characterized by NADPH oxidase expression and neovascularization in an aortic transplantation model [0.03%]
基于NADPH氧化酶表达和新生血管形成早期外层活化的移植主动脉模型特征研究
Mengyao Sun,Jian Ji,Xiaotong Guo et al.
Mengyao Sun et al.
Increasing evidence has suggested that arterial adventitia may contribute to pathological vessel remodeling by producing reactive oxygen species and promoting neovascularization. However, these processes have not been studied yet in transpl...
Dragana Robajac,Valerie Vanhooren,Romana Masnikosa et al.
Dragana Robajac et al.
Posttranslational modifications (PTM) which accompany pathological conditions affect protein structure, characteristics and modulate its activity. Glycosylation is one of the most frequent PTM influencing protein folding, localisation and f...
New insights on the palate, lung, and nasal epithelium clone (PLUNC) proteins: Based on molecular and functional analysis of its homolog of YH1/SPLUNC1 [0.03%]
基于YH1/SPLUNC1同源分子及功能分析的PLUNC蛋白新见解
Hui Liu,Xiangning Zhang,Jingjing Wu et al.
Hui Liu et al.
The palate, lung, and nasal epithelium clone (PLUNC) proteins are intricate immune molecules and arisen questions from them are still unresolved. In order to identify the role of PLUNC family proteins, we had analyzed its homolog protein YH...
Analysis of mitochondrial DNA heteroplasmic mutations A1555G, C3256T, T3336C, С5178А, G12315A, G13513A, G14459A, G14846А and G15059A in CHD patients with the history of myocardial infarction [0.03%]
汉族患者中线粒体DNA杂合突变A1555G、C3256T、T3336C、С5178А、G12315A、G13513A、G14459A、G14846А和G15059A与冠心病及急性心肌梗死相关性分析
Konstantin Y Mitrofanov,Andrey V Zhelankin,Gulnara M Shiganova et al.
Konstantin Y Mitrofanov et al.
The present study was undertaken in order to advance our earlier studies directed to define genetic risk of atherosclerotic vascular lesion development on a base on the analysis of sets of mutational load relevant to the mitochondrial genom...
Droplet digital polymerase chain reaction detection of HER2 amplification in formalin fixed paraffin embedded breast and gastric carcinoma samples [0.03%]
福尔马林固定石蜡包埋的乳腺癌和胃癌组织样本中HER2扩增的微滴式数字聚合酶链反应检测方法
Yazhen Zhu,Dan Lu,Maruja E Lira et al.
Yazhen Zhu et al.
Rationale: Human epidermal growth factor receptor 2 (HER2) is a key driver of tumorigenesis, and over-expression as a result of HER2 gene amplification has been observed in a number of solid tumors. Recently HER2 has beco...
Genetic alterations in endometrial cancer by targeted next-generation sequencing [0.03%]
靶向下一代测序在子宫内膜癌中的基因改变研究
Ya-Sian Chang,Hsien-Da Huang,Kun-Tu Yeh et al.
Ya-Sian Chang et al.
Many genetic factors play important roles in the development of endometrial cancer. The aim of this study was to investigate genetic alterations in the Taiwanese population with endometrial cancer. DNA was extracted from 10 cases of fresh-f...
Comparative evaluation of the GP5+/6+, MY09/11 and PGMY09/11 primer sets for HPV detection by PCR in oral squamous cell carcinomas [0.03%]
用于口腔鳞状细胞癌样本中HPV检测的GP5+/6+、MY09/11和PGMY09/11引物组的比较评价研究
Sibele Morais Miyata Erhart,Elena Riet Correa Rivero,Maria Luiza Bazzo et al.
Sibele Morais Miyata Erhart et al.
The aim of this study was to evaluate the use of GP5+/6+, MY09/11 and PGMY09/11 primer sets for the detection of human papillomavirus (HPV) DNA by single step polymerase chain reaction (PCR) and nested PCR in formalin-fixed and paraffin-emb...
Comparative Study
Experimental and molecular pathology. 2016 Feb;100(1):13-6. DOI:10.1016/j.yexmp.2015.11.024 2016
Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation-induced cell apoptosis via sphingosine kinase 2 and FAK/AKT pathway [0.03%]
缺氧预处理通过SphK2和FAK/Akt信号通路保护心肌细胞免受缺氧复氧诱导的细胞凋亡损伤
Ruxin Zhang,Ling Li,Li Yuan et al.
Ruxin Zhang et al.
Previous studies have demonstrated that hypoxic preconditioning (HPC) alleviates hypoxia/reoxygenation (H/R) injury. However, the impact and mechanism involved were not fully understood. This study aimed to evaluate the effect of HPC on H/R...