Piperine and piperine-loaded albumin nanoparticles ameliorate adjuvant-induced arthritis and reduce IL-17 in rats [0.03%]
胡椒碱及白蛋白纳米粒包载胡椒碱对佐剂性关节炎大鼠的治疗作用及其对Th17细胞的影响
Nasser Gholijani,Negar Azarpira,Samira-Sadat Abolmaali et al.
Nasser Gholijani et al.
Aim: Rheumatoid arthritis (RA) is one of the most common chronic, inflammatory, autoimmune diseases affecting mainly the joints. Piperine (PIP), an alkaloid found in black pepper, has anti-inflammatory properties and its ...
Kulthida Vaeteewoottacharn,Sakda Waraasawapati,Phattarin Pothipan et al.
Kulthida Vaeteewoottacharn et al.
Immune evasion is one of the mechanisms by which cancer cells acquire immunity during cancer development and progression. One of these is the increased expression of cluster of differentiation 47 (CD47), a transmembrane glycoprotein that pr...
Corrigendum to "Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST" [Experimental and Molecular Pathology 139 (2024) 104922] [0.03%]
关于“抗体药物偶联物靶向细胞粘附分子1对小肠GIST细胞系的抗肿瘤效应”的勘误声明[实验与分子病理学杂志139(2024)104922]
Makoto Yoshida,Jiayin Yuan,Takako Kihara et al.
Makoto Yoshida et al.
Published Erratum
Experimental and molecular pathology. 2024 Dec:140:104934. DOI:10.1016/j.yexmp.2024.104934 2024
Effects of different hypoxia exposure on myeloid-derived suppressor cells in mice [0.03%]
不同缺氧暴露对小鼠髓系源抑制细胞的影响
Qiying Xu,Huifang Liu,Yi Ye et al.
Qiying Xu et al.
For many people living at high altitudes for long or short periods of time, hypoxia is a challenge affecting many aspects of the body, including the immune system. Recently, myeloid-derived suppressor cells (MDSCs) have emerged as an immune...
Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro [0.03%]
大麻植物中的药用成分对体外培养的炎症Treg和Th17细胞的抗炎作用
Kyle B C Tan,H Denis Alexander,James Linden et al.
Kyle B C Tan et al.
Aims: Phytocannabinoids and terpenes from Cannabis sativa have demonstrated limited anti-inflammatory and analgesic effects in several inflammatory conditions. In the current study, we test the hypothesis that phytocannab...
Age-related decline in goblet cell numbers and mucin content of the human colon: Implications for lower bowel functions in the elderly [0.03%]
年龄相关的人结肠杯状细胞数量和粘蛋白含量的下降及其对老年人结肠功能的影响
Nicholas Baidoo,Gareth J Sanger
Nicholas Baidoo
Background & aims: Older people experience a greater incidence of lower bowel disorders, including constipation. Causes can include factors associated with growing older, such as use of medications or disease, but compoun...
Dexamethasone attenuates low-frequency brainwave disturbances following acute seizures induced by pentylenetetrazol in Wistar rats [0.03%]
地塞米松能缓解戊四氮诱发急性癫痫后Wistar大鼠低频脑电波异常
Rafaella Marques Ribeiro,Esther Padilha da Silveira,Vitoria Corrêa Santos et al.
Rafaella Marques Ribeiro et al.
Seizures are neurological disorders triggered by an imbalance in the activity of excitatory and inhibitory neurotransmitters in the brain. When triggered chronically, this imbalance can lead to epilepsy. Critically, many of the affected ind...
Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST [0.03%]
针对小肠GIST细胞的抗体-药物偶联物靶向细胞黏附分子1的抗肿瘤效应
Makoto Yoshida,Jiayin Yuan,Takako Kihara et al.
Makoto Yoshida et al.
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the alimentary tract. The prognosis depends on the primary site, and small intestinal GISTs have a worse prognosis than gastric GISTs. Molecularly targeted drugs ...
The relationship between tumor immunity and the cGAS-STING pathway in breast cancer: An immunohistochemical study [0.03%]
肿瘤免疫与cGAS-STING信号通路在乳腺癌中的关系：一项免疫组化研究
Haruto Nishida,Naoto Ohara,Ami Kato et al.
Haruto Nishida et al.
Breast cancer (BC) is classified into four major histological subtypes, namely luminal A, luminal B, HER2, and basal-like, and its treatment is based on these subtypes. The use of immune checkpoint inhibitors against BC depends on the expre...
Validation of a targeted next-generation sequencing panel for pancreatic ductal adenocarcinomas [0.03%]
胰腺导管腺癌靶向下一代测序 panels 的验证研究
Marie-Lucie Racu,Andrea Alex Schiavo,Claude Van Campenhout et al.
Marie-Lucie Racu et al.
Pancreatic ductal adenocarcinoma (PDAC) is reported to be amongst the cancers with the lowest survival rate at 5 years. In the present study we aimed to validate a targeted next-generation sequencing (tNGS) panel to use in clinical routine,...