The role of lactate and lactylation in ischemic cardiomyopathy: Mechanisms and gene expression [0.03%]
乳酸和乳酰化在缺血性心肌病中的作用:机制与基因表达
Mei Zhang,Xue Kong,Chenlu Wu et al.
Mei Zhang et al.
Ischemic cardiomyopathy (ICM) is a significant global public health issue, with its pathophysiology encompassing atherosclerotic plaque formation, thrombosis, hypoperfusion, ischemic cell death, and left ventricular remodeling. Lactate is n...
Dynamic full-field optical coherence tomography for extemporaneous high-resolution imaging of adrenal glands [0.03%]
用于肾上腺即刻高分辨成像的动态全场光学相干断层扫描术
Irene A Spiridon,Michel Vix,Didier Mutter et al.
Irene A Spiridon et al.
Background: There is an interindividual variance in postoperative adrenocortical capacity, and the minimal functional remnant size is unknown. New imaging technologies may allow for improved intraoperative assessment of a...
Diagnostic next-generation sequencing to detect MYD88 L265P in Lymphoplasmacytic lymphoma compared to ddPCR [0.03%]
淋巴浆细胞性淋巴瘤中诊断性新一代测序检测MYD88 L265P与ddPCR的对比研究
Lauren M Wainman,Guohong Huang,Donald C Green et al.
Lauren M Wainman et al.
Lymphoplasmacytic lymphoma (LPL) is a B-cell lymphoproliferative disorder typically involving the bone marrow with infiltration by small lymphocytes and plasma cells. Studies have identified MYD88 L265P mutation as a diagnostic marker to di...
Hyperinsulinemic male LEW.1WR1 rats show early signs of impaired liver metabolism [0.03%]
高胰岛素血症的公LEW.1WR1大鼠表现出肝代谢受损的早期迹象
Madushika Wimalarathne,Bailey L Bowser,Albert B Arul et al.
Madushika Wimalarathne et al.
Weanling LEW.1WR1 (1WR1) rats are susceptible to type 1 diabetes (T1D) and hyperinsulinemic. Similar to human patients with T1D, these animals are susceptible to developing fatty liver infiltrates. Insulin resistance-related steatosis can l...
Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer [0.03%]
基质金属蛋白酶-3与前列腺癌细胞增殖和迁移有关是一项强大的预后因素
Ai Sato,Kiyoshi Takagi,Mio Yamaguchi-Tanaka et al.
Ai Sato et al.
Prostate cancer is a common malignancy in men around the world, and it is crucial to explore novel biomarkers to improve its treatment. Prostate cancer cells typically invade the surrounding stroma, and remodeling of the extracellular matri...
Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice [0.03%]
地中海饮食可改善肝健康但与西方饮食相比不能预防阿魏酸甲烷致A/J小鼠结肠肿瘤发生的发展学派
Weimin Guo,Nicholas Crossland,Jimmy W Crott
Weimin Guo
Introduction: Abundant evidence indicates that the Mediterranean (MED) diet pattern is beneficial for health, especially cardiovascular health. Epidemiological evidence indicates that the MED diet also affords protection ...
Role of A1 adenosine receptor in cardiovascular diseases: Bridging molecular mechanisms with therapeutic opportunities [0.03%]
A1腺苷受体在心血管疾病中的作用:连接分子机制与治疗机会
Warisara Parichatikanond,Ratchanee Duangrat,Narawat Nuamnaichati et al.
Warisara Parichatikanond et al.
Adenosine serves as a critical homeostatic regulator, exerting influence over physiological and pathological conditions in the cardiovascular system. During cellular stress, increased extracellular adenosine levels have been implicated in c...
Modulation of IL-6 receptor/STAT3 downstream signaling in rheumatoid arthritis patients [0.03%]
类风湿关节炎患者IL-6受体/STAT3下游信号通路的调节
Fabio Cacciapaglia,Simone Perniola,Stefano Stano et al.
Fabio Cacciapaglia et al.
Interleukin-6 (IL-6) is a relevant cytokine in rheumatoid arthritis (RA) pathogenesis, potentially activating Janus kinases (JAK)-1, -2, and tyrosine kinase 2 (TYK2), and thus, three signal transducer and activator of transcription (STAT)-1...
Transcriptomic analysis of the HPT axis in a model of oligoasthenozoospermia induced by Adenine in rats [0.03%]
腺嘌呤诱导的大鼠少弱精子症模型下HPT轴的转录组分析
Nan Yang,Xiao-Ge Wei,Kaiying Li et al.
Nan Yang et al.
Male infertility is most commonly caused by oligozoospermia, and its pathogenesis is still poorly understood at the molecular level. This study used RNA sequencing (RNA-Seq) technology to identify candidate genes and regulatory pathways tha...
Corrigendum to "Suppression of miR-143-3p contributes to the anti-fibrosis effect of atorvastatin on myocardial tissues via the modulation of Smad2 activity" [Experimental and Molecular Pathology 112 (2020) 104346] [0.03%]
关于“miR-143-3p的抑制作用通过调节Smad2活性对阿托伐他汀抗心肌纤维化的影响”一文的勘误通知(实验与分子病理学杂志,2020,112(104346))
Bo Yu,Ming Yu,Hongli Zhang et al.
Bo Yu et al.
Published Erratum
Experimental and molecular pathology. 2024 Dec:140:104945. DOI:10.1016/j.yexmp.2024.104945 2024