From asbestos exposure to carcinogenesis: Transcriptomic signatures in malignant pleural mesothelioma [0.03%]
从石棉暴露到致癌:恶性胸膜间皮瘤中的转录组标志物
Diletta Rosati,Bianca Giulia Maurizi,Viola Bianca Serio et al.
Diletta Rosati et al.
Background: The incidence of malignant pleural mesothelioma (MPM) has surged due to widespread asbestos exposure, particularly since the mid-20th century. Despite significant advancements in cancer treatment, an effective...
Estrogen induces the alternative activation of macrophages through binding to estrogen receptor-alpha [0.03%]
雌激素通过与雌激素受体-α结合诱导巨噬细胞向功能替代型表型分化
Amina Belboul,Jason Ashworth,Abdulmannan Fadel et al.
Amina Belboul et al.
Age-related impaired wounds represent a major health burden resulting in considerable morbidity and mortality in the elderly. When injury occurs, monocytes migrate to the damaged site and undergo differentiation into tissue-resident macroph...
m6A demethylase FTO/ALKBH5 promotes diabetes-induced endothelial cell dysfunction by negatively regulating lncRNA H19 [0.03%]
FTO/ALKBH5 去甲基化酶通过负向调节长链非编码 RNA H19 促进糖尿病引起的血管内皮细胞功能障碍
Yanli Luo,Wanjun Luo,Yanan Cao et al.
Yanli Luo et al.
Endothelial cell dysfunction induced by glucose is the most important cause of diabetic vascular complications, which are the leading causes of blindness, disability, renal failure, heart failure, stroke, and even death in diabetic patients...
The multifunctional protein CCN1/CYR61: Bridging physiology and disease [0.03%]
多功能蛋白CCN1/CYR61:连接生理和疾病
Racha Kerek,Joe Sawma Awad,Mariam Bassam et al.
Racha Kerek et al.
The matricellular protein CYR61/CCN1 is a member of the CCN protein family that plays significant roles in a broad range of physiological processes, including development, tissue repair, and inflammation, among others. CCN1 is also implicat...
Cross-feeding between beneficial and pathogenic bacteria to utilize eukaryotic host cell-derived sialic acids and bacteriophages shape the pathogen-host interface milieu [0.03%]
益生菌和致病菌之间交叉喂养利用真核宿主细胞来源的唾液酸及噬菌体影响病原-宿主界面微环境
Darab Ghadimi,Regina Fölster-Holst,Sophia Blömer et al.
Darab Ghadimi et al.
Under an inflamed-intestinal milieu, increased free sialic acids are associated with the overgrowth of some pathogenic bacterial strains. Recently, the protective immunomodulatory activity of gut bacteriophages (phages) has also been highli...
Retraction notice to "Matrine protects neuro-axon from CNS inflammation-induced injury" [Experimental and Molecular Pathology 98 (2015) 124-130] [0.03%]
撤销《小檗胺保护神经轴索免受中枢神经系统炎症引起的损伤》[实验与分子病理学(2015),98(1):124-130]的撤稿通知
Quan-Cheng Kan,Peng Lv,Xiao-Jian Zhang et al.
Quan-Cheng Kan et al.
Morphological characteristics, extracellular vesicle structure and stem-like specificity of human follicular fluid cell subpopulation during osteodifferentiation [0.03%]
人骨细胞分化过程中卵泡液细胞亚群的形态特征、胞外囊结构和干细胞特异性
Wiesława Kranc,Mariusz Kaczmarek,Katarzyna Kowalska et al.
Wiesława Kranc et al.
Extracellular vesicles can play an important role in the processes occurring after stem cell transplantation, preventing cell apoptosis, stimulating immunological processes, and promoting the synthesis of extracellular matrix. Human follicu...
The effects of melatonin on differentiated C2C12 myotubes in the absence of pathology: An oxygen-sparing action and enhancement of pro-survival signalling pathways [0.03%]
褪黑素对正常分化C2C12肌管细胞作用的研究: 一种节省氧气的作用及促进生存信号通路的增强
Garth Wentley,Russel J Reiter,Yong-Xiao Wang et al.
Garth Wentley et al.
Previous research has demonstrated that melatonin protects against muscle damage while also improving the performance of injured muscle. However, its impact on healthy skeletal muscle remains largely unexplored. We exposed differentiated C2...
Gut-lung Axis mediates asthma pathogenesis: Roles of dietary patterns and their impact on the gut microbiota [0.03%]
肠道-肺轴介导哮喘的发生发展:饮食模式及其对肠道菌群影响的作用
Yanbo Liu,Ying Zhou,Haoyue Zhang et al.
Yanbo Liu et al.
The gut-lung axis, a vital signaling network linking the gastrointestinal and pulmonary systems, regulates immune responses and the progression of respiratory diseases. Nutritional components can modulate the gut microbiome and regulate the...
Advances in sepsis research: Insights into signaling pathways, organ failure, and emerging intervention strategies [0.03%]
脓毒症研究进展:信号通路、器官衰竭及新兴干预策略的见解
Yehua Li,Siying Ren,Shenao Zhou
Yehua Li
Sepsis is a complex syndrome resulting from an aberrant host response to infection. A hallmark of sepsis is the failure of the immune system to restore balance, characterized by hyperinflammation or immunosuppression. However, the net effec...