The association between abnormal glucose metabolism and rheumatoid arthritis [0.03%]
异常糖代谢与类风湿性关节炎的关系
Xiaoyu Zhang,Fanyan Meng,Zhidan Wang et al.
Xiaoyu Zhang et al.
The research has found that the incidence of rheumatoid arthritis (RA) combined with Type 2 Diabetes Mellitus (T2DM) and insulin resistance (IR) is higher than that in the general population. This indicates that there is an association mech...
Genetic and epigenetic determinants of fetal alcohol spectrum disorders: Toward a precision medicine approach [0.03%]
胎儿酒精谱系障碍的遗传和表观遗传决定因素:迈向精准医学方法
Francesco Sessa,Marco Carotenuto,Davide Ferorelli et al.
Francesco Sessa et al.
Fetal Alcohol Spectrum Disorders (FASD) encompass a continuum of neurodevelopmental and physical impairments resulting from prenatal alcohol exposure (PAE). Despite widespread recognition of ethanol's teratogenic effects, the clinical varia...
Celecoxib and naproxen disrupt autophagy and activate EGR1 in kidney tubules [0.03%]
塞来昔布和萘普生干扰自噬并激活肾小管中的EGR1
Samaneh Haghighi,Arezoo Haghighi,Zoltán S Zádori et al.
Samaneh Haghighi et al.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for their analgesic effects, although the possible COX-independent impact on the kidneys is largely unknown. Kidney damage is often associated with defective autophagy and autoph...
Retraction notice to "Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone" [Experimental and Molecular Pathology 76 (2004) 242-252] [0.03%]
有关干扰素α-2b抑制全长HCV1a感染性克隆的负链RNA和蛋白质表达的文章的撤稿通知[实验与分子病理学2004年76卷242-252页]
Ramesh Prabhu,Virendra Joshi,Robert F Garry et al.
Ramesh Prabhu et al.
Ayako Inoda,Keiko Suzuki,Hiroyuki Tomita et al.
Ayako Inoda et al.
The endothelial glycocalyx, a carbohydrate-rich layer lining the vascular endothelium, plays a critical role in maintaining vascular homeostasis by regulating permeability, leukocyte adhesion, and inflammatory signaling. Its degradation has...
Cell-specific functions of STAT3 in osteoarthritis and its therapeutic potential [0.03%]
STAT3在骨关节炎中的细胞特异性功能及其治疗潜力
Cai Zhang,Jingyuan Gao,Lu Chen et al.
Cai Zhang et al.
Osteoarthritis (OA) represents a prevalent chronic joint disorder, which is pathologically characterized by cartilage degeneration. At present, effective therapeutic interventions for OA remains relatively infrequent, highlighting the urgen...
Automated quantification of collagen proportionate area correlates with molecular and histological markers of fibrosis in CCl4-treated rats [0.03%]
胶原含量定量与四氯化碳所致大鼠肝纤维化分子和组织学标志物的相关性研究
Bernie Efole,Mathilde Mouchiroud,Alexandra Dubé et al.
Bernie Efole et al.
Liver fibrosis results from chronic liver injury and is characterized by excessive accumulation of extracellular matrix due to sustained wound-healing responses. Although histological evaluation remains the gold standard for fibrosis assess...
Angelo Santoro,Yuri Vincenzo Ferrara,Alfonso De Angelis
Angelo Santoro
Cystinosis is a autosomal recessive lysosomal storage disorder caused by mutations in the CTNS gene, which encodes cystinosin, a cystine transporter. The defective function of cystinosin leads to cystine accumulation in the lysosome, result...
Platelet-derived growth factor-C contributes to kidney inflammation in experimental hypertension with little effect on the peritubular capillary network [0.03%]
血小板源性生长因子-C在实验性高血压肾炎中的作用及其对肾周毛细血管网络影响较小
Ina V Martin,Christian Dippel,Eva M Buhl et al.
Ina V Martin et al.
Background and aims: Platelet-Derived Growth Factor (PDGF)-C plays a significant role in kidney fibrosis, angiogenesis, and hypertension. While its involvement in the healing of damaged glomerular capillaries is well reco...
Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma [0.03%]
过氧化物酶在肾细胞癌的瘤内毛细血管和临近透明细胞周围的近端小管上皮细胞中高表达
Roberto Silva,Jorge Reis Almeida,Ana Rita Coelho et al.
Roberto Silva et al.
Peroxidasin (PXDN), is a heme peroxidase with a critical role in the crosslinking of type IV collagen, being essential for basement membrane integrity. Overexpression of PXDN has been associated with poor clinical outcomes in many cancers; ...