Viral diversity limits immune diversity in asymptomatic phase of HIV infection [0.03%]
在HIV感染无症状期,病毒多样性限制了免疫多样性
Shingo Iwami,Shinji Nakaoka,Yasuhiro Takeuchi
Shingo Iwami
We propose a new diversity threshold theory which states that the specific CTLs to the viral strain become inactivated (that is, some HIV strain can escape from its specific immune response) when the diversity of HIV strains exceeds some th...
Simon Myers,Charles Fefferman,Nick Patterson
Simon Myers
It is well known that the neutral allelic frequency spectrum of a population is affected by the history of population size. A number of authors have used this fact to infer history given observed allele frequency data. We ask whether perfec...
Eli E Goldwyn,Alan Hastings
Eli E Goldwyn
While spatial synchrony of oscillating populations has been observed in many ecological systems, the causes of this phenomenon are still not well understood. The most common explanations have been the Moran effect (synchronous external stoc...
Analytic approximation of spatial epidemic models of foot and mouth disease [0.03%]
口蹄疫空间流行病模型的解析近似方法研究
P E Parham,B K Singh,N M Ferguson
P E Parham
The effect of spatial heterogeneity in epidemic models has improved with computational advances, yet far less progress has been made in developing analytical tools for understanding such systems. Here, we develop two classes of second-order...
Manojit Roy,Robert D Holt
Manojit Roy
The integration of infectious disease epidemiology with community ecology is an active area of research. Recent studies using SI models without acquired immunity have demonstrated that predation can suppress infectious disease levels. The a...
The ideal free distribution: a review and synthesis of the game-theoretic perspective [0.03%]
理想自由分布:博弈论视角的综述与合意
Vlastimil Krivan,Ross Cressman,Candace Schneider
Vlastimil Krivan
The Ideal Free Distribution (IFD), introduced by Fretwell and Lucas in [Fretwell, D.S., Lucas, H.L., 1970. On territorial behavior and other factors influencing habitat distribution in birds. Acta Biotheoretica 19, 16-32] to predict how a s...
E A Thompson
E A Thompson
In this note, we present the continuous-time Markov rate matrix that models identity by descent (ibd) patterns among four chromosomes in a population. The equilibrium distribution of this Markov process along a chromosome is the set of 4-ge...
Long-range correlations improve understanding of the influence of network structure on contact dynamics [0.03%]
长程关联提升对网络结构影响接触动态的理解
N Peyrard,U Dieckmann,A Franc
N Peyrard
Models of infectious diseases are characterized by a phase transition between extinction and persistence. A challenge in contemporary epidemiology is to understand how the geometry of a host's interaction network influences disease dynamics...
Zhilan Feng,Rongsong Liu,Donald L DeAngelis
Zhilan Feng
We explore the impact of plant toxicity on the dynamics of a plant-herbivore interaction, such as that of a mammalian browser and its plant forage species, by studying a mathematical model that includes a toxin-determined functional respons...
Zhong-Wei Jia,Gong-You Tang,Zhen Jin et al.
Zhong-Wei Jia et al.
This paper presents two new theoretical frameworks to investigate the impact of immigration on the transmission dynamics of tuberculosis. For the basic model, we present new analysis on the existence and stability of equilibria. Then, we us...