Conditional gene genealogies given the population pedigree for a diploid Moran model with selfing [0.03%]
二倍体 Moran 自交模型中给定群体世系的条件基因世系
Maximillian Newman,John Wakeley,Wai-Tong Louis Fan
Maximillian Newman
We introduce a stochastic model of a population with overlapping generations and arbitrary levels of self-fertilization versus outcrossing. We study how the global graph of reproductive relationships, or population pedigree, influences the ...
Seth D Temple,Elizabeth A Thompson
Seth D Temple
If two haplotypes share the same alleles for an extended gene tract, these haplotypes are likely to be derived identical-by-descent from a recent common ancestor. Identity-by-descent segment lengths are correlated via unobserved ancestral t...
The TMRCA of general genealogies in populations with deterministically varying size [0.03%]
具有确定变化人口规模的种群中一般系谱的TMRCA
Alejandro H Wences,Lizbeth Peñaloza,Matthias Steinrücken et al.
Alejandro H Wences et al.
We study the time to the most recent common ancestor (TMRCA) of a sample of finite size in a wide class of genealogical models for populations with deterministically varying size. This is made possible by recently developed results on inhom...
Alan Flatrès,Geoff Wild
Alan Flatrès
Individuals can be subject to brood failure for many reasons, e.g. egg predation. Some species have adopted a strategy to compensate for fitness loss due to brood failure. In some bird species, individuals that experience brood failure can ...
Using mathematical constraints to explain narrow ranges for allele-sharing dissimilarities [0.03%]
利用数学约束解释等位基因共享差异的狭窄范围
Xiran Liu,Zarif Ahsan,Noah A Rosenberg
Xiran Liu
Allele-sharing dissimilarity (ASD) statistics are measures of genetic differentiation for pairs of individuals or populations. Given the allele-frequency distributions of two populations-possibly the same population-the expected value of an...
Parthenogenesis, sexual conflict, and selection on fertilization rates in switching environments [0.03%]
倍性转换、性别冲突和交配率的选择
Xiaoyuan Liu,Jon W Pitchford,George W A Constable
Xiaoyuan Liu
In the face of varying environments, organisms exhibit a variety of reproductive modes, from asexuality to obligate sexuality. Should reproduction be sexual, the morphology of the sex cells (gametes) produced by these organisms has importan...
Mathematical bounds on r2 and the effect size in case-control genome-wide association studies [0.03%]
病例对照全基因组关联研究中r2和效应大小的数学限制条件分析
Sanjana M Paye,Michael D Edge
Sanjana M Paye
Case-control genome-wide association studies (GWAS) are often used to find associations between genetic variants and diseases. When case-control GWAS are conducted, researchers must make decisions regarding how many cases and how many contr...
Evolution between two competing macrophyte populations along a resource gradient leads to collapse in a bistable lake ecosystem [0.03%]
资源梯度下两种挺水植物竞争种群的进化导致双稳态湖泊生态系统崩溃
Sirine Boucenna,Gael Raoul,Vasilis Dakos
Sirine Boucenna
While it is known that shallow lake ecosystems may experience abrupt shifts (ie tipping points) from a clear water state to a contrasting turbid alternative state as a result of eutrophication, the role of evolutionary processes and the imp...
Fabian Freund,Johannes Wirtz,Yichen Zheng et al.
Fabian Freund et al.
Copy number of genes in gene families can be highly variable among individuals and may continue to change across generations. Here, we study a model of duplication-selection interaction, which is related to Haigh's mutation-selection model ...
Eco-evolutionary dynamics of anthelmintic resistance in soil-transmitted helminths [0.03%]
土壤传播线虫的抗虫演化动态
Swati Patel,Kelsey Lyberger,Carolin Vegvari et al.
Swati Patel et al.
Anthelmintic resistance (AR) of soil-transmitted helminth parasites against the most widely available drugs is an ongoing concern for both human-infecting and livestock-infecting species. There has been substantial evidence of AR in livesto...