Amitosis as a strategy of cell division-Insight from the proliferation of Tetrahymena thermophila macronuclei [0.03%]
无有丝分裂细胞增殖策略——模式生物 Thermophila tetrahymana 宏核的自我复制机制研究
Yun-Xin Fu,Guangying Wang,Kai Chen et al.
Yun-Xin Fu et al.
Cell division is a necessity of life which can be either mitotic or amitotic. While both are fundamental, amitosis is sometimes considered a relic of little importance in biology. Nevertheless, eukaryotes often have polyploid cells, includi...
Gain-loss-duplication models for copy number evolution on a phylogeny: Exact algorithms for computing the likelihood and its gradient [0.03%]
谱系上基因组拷贝数进化的增减扩模型：似然及其梯度的精确算法计算问题
Miklós Csűrös
Miklós Csűrös
Gene gain-loss-duplication models are commonly based on continuous-time birth-death processes. Employed in a phylogenetic context, such models have been increasingly popular in studies of gene content evolution across multiple genomes. Whil...
A hidden Markov model to estimate homozygous-by-descent probabilities associated with nested layers of ancestors [0.03%]
用于估计多层祖先背景下同源杂合概率的隐马尔可夫模型
Tom Druet,Mathieu Gautier
Tom Druet
Inbreeding results from the mating of related individuals and has negative consequences because it brings together deleterious variants in one individual. Genomic estimates of the inbreeding coefficients are preferred to pedigree-based esti...
Extinction threshold and large population limit of a plant metapopulation model with recurrent extinction events and a seed bank component [0.03%]
具有反复灭绝事件和种子库成分的植物元种群模型的灭绝阈值和大人口限制
Apolline Louvet
Apolline Louvet
We introduce a new model for plant metapopulations with a seed bank component, living in a fragmented environment in which local extinction events are frequent. This model is an intermediate between population dynamics models with a seed ba...
Gene drives and population persistence vs elimination: The impact of spatial structure and inbreeding at low density [0.03%]
基因驱动和种群持续存在与消除：低密度下的空间结构和近交的影响
P J Beaghton,Austin Burt
P J Beaghton
Synthetic gene drive constructs are being developed to control disease vectors, invasive species, and other pest species. In a well-mixed random mating population a sufficiently strong gene drive is expected to eliminate a target population...
Noah A Rosenberg,Maciej F Boni
Noah A Rosenberg
Evolution of cooperation with respect to fixation probabilities in multi-player games with random payoffs [0.03%]
具有随机收益的多玩家博弈中合作以固定概率进化的研究
Dhaker Kroumi,Éloi Martin,Sabin Lessard
Dhaker Kroumi
We study the effect of variability in payoffs on the evolution of cooperation (C) against defection (D) in multi-player games in a finite well-mixed population. We show that an increase in the covariance between any two payoffs to D, or a d...
The effects of epistasis and linkage on the invasion of locally beneficial mutations and the evolution of genomic islands [0.03%]
上位性与连锁对局部有利突变的入侵以及基因组岛屿进化的影响
Martin Pontz,Reinhard Bürger
Martin Pontz
We study local adaptation of a peripheral population by investigating the fate of new mutations using a haploid two-locus two-allele continent-island migration model. We explore how linkage, epistasis, and maladaptive gene flow affect the i...
Kenichi Aoki,Joe Yuichiro Wakano
Kenichi Aoki
We propose a predator-prey model to explain diachronic changes in Palaeolithic diet breadth. The fraction of rapidly-reproducing hard-to-catch hares and birds among small animals in the hominin diet shows a significant increase between the ...
The curse of the plateau. Measuring confidence in human mortality estimates at extreme ages [0.03%]
极端年龄的人口死亡率估计的置信度测量：“平台效应”的诅咒
Carlo Giovanni Camarda
Carlo Giovanni Camarda
In recent years, the importance of describing mortality at the limits of the life span has led to a number of relevant and controversial studies. Whereas considerable efforts have been devoted to collecting data and estimating models on the...