Classification prediction of drug target binding affinity based on the MolrProtTrans model [0.03%]
基于MolrProtTrans模型的药物靶点结合亲和力分类预测
Yicun Lin,Yuanfeng Li,Wei Sun et al.
Yicun Lin et al.
Predicting drug-target interactions is essential for virtual drug screening. While many models predict the binding affinity between small molecules and proteins, they often overemphasize molecular features while overlooking important protei...
Single-entity dual-emissive MOF platform for reliable ratiometric point-of-care detection of amoxicillin residues [0.03%]
基于单一实体的双发射MOF平台用于可靠的比例型阿莫西林残留体外检测
Sameera Sh Mohammed Ameen,Fiasal K Algethami,Khalid M Omer et al.
Sameera Sh Mohammed Ameen et al.
In fluorescence-based sensing, self-referencing ratiometric analysis offers a significant advantage over external referencing by integrating both the probe and reference signals within a single material, rather than relying on two separate ...
Optimized purification workflow for advanced eEF1A studies: Impact of His-tagging on stability, functionality, and yield [0.03%]
用于高级eEF1A研究的优化纯化工作流程：组氨酸标签对稳定性和功能的影响及产量的影响
Pernille Nedergaard Madsen,Pernille Baden Jørgensen,Mille Varisbøl Clausen et al.
Pernille Nedergaard Madsen et al.
The eukaryotic elongation factor 1A (eEF1A) is crucial for translation, delivering aminoacyl-tRNAs to the ribosomal A site. While its bacterial counterpart, elongation factor thermo unstable (EF-Tu), has been extensively studied, the canoni...
Advances in the detection of azodicarbonamide and the metabolic product semicarbazide [0.03%]
偶氮甲酰胺及其代谢产物半胱氨酸亚硝酸盐检测方法的新进展
Zijuan Miao,Bowen Kan,Pan Liu et al.
Zijuan Miao et al.
Azodicarbonamide (ADA) is widely used as a foaming and oxidizing agent in the food and plastic industries. However, long-term exposure to it could cause serious health problems. Its metabolic product, semicarbazide (SEM), has raised health ...
Structural, optical, and electrochemical characterization of TiO2-x thin films for non-enzymatic amperometric glucose sensing [0.03%]
用于安培法无酶葡萄糖检测的TiO2-x薄膜的结构、光学和电化学特性分析
J K Olarte Villamizar,M Zapata Torres,N Cruz González et al.
J K Olarte Villamizar et al.
This work presents a novel approach to non-enzymatic glucose sensing based on oxygen-deficient titanium dioxide (TiO2-x) thin films deposited on metallic titanium substrates. The TiO2-x films were fabricated via RF magnetron reactive sputte...
Affinity-based selection of anti-Feline Leukaemia Virus p27 monoclonal antibodies for efficient lateral flow assay development [0.03%]
基于亲和力的抗猫白血病病毒p27单克隆抗体的选择及其在侧向流动分析中的应用开发
Hadyn Duncan,Elisabeth Domingo-Contreras,Sotirios Athanasiou et al.
Hadyn Duncan et al.
Traditional diagnostic methods like RT-PCR and proviral DNA PCR have limitations, underscoring the need for swift, sensitive alternatives such as lateral flow immunoassays (LFIA). Yet, efficiently identifying monoclonal antibody (mAb) pairs...
Djamali Muhoza,Emily P Esquivel,Stacy R Hunter et al.
Djamali Muhoza et al.
The serine/threonine kinase PAK1 serves as a mediator of cytoskeletal reorganization and cancer-related signaling downstream of the small GTPases. Due to the challenges in purifying PAK1 complexes, a 46-residue peptide from PAK1, is widely ...
Rapid purification of DNA samples from dextran sodium sulfate (DSS) contaminants [0.03%]
一种快速去除十二水硫酸钠(DSS)污染的DNA纯化方法
Adam Yeh,James Saliba,Volker Blank
Adam Yeh
Dextran sodium sulfate (DSS) is widely used to model colonic inflammation and colorectal cancer. However, it is a potent inhibitor of DNA polymerase, necessitating its removal prior to downstream analysis. Currently, there is no robust, wid...
Corrigendum to"Development of a green polymer-based sensor for enhanced iron detection in diverse biological, food and environmental matrices" [Analyt. Biochem. 705 (2025) 115927] [0.03%]
关于“一种基于绿色聚合物的传感器的发展，用于在各种生物、食品和环境基质中增强铁检测”的勘误说明
Rania A Hussien
Rania A Hussien
Published Erratum
Analytical biochemistry. 2025 Nov 17:116012. DOI:10.1016/j.ab.2025.116012 2025
Comparative Analysis of Common Potency Assays for Assessing Human TNF-alpha Neutralising Antibodies [0.03%]
人TNF-α抗体中和活性的常用检测方法比较分析
Rithwik Pradeep,Alexander Zhdanov,Evin Allen
Rithwik Pradeep
Tumour necrosis factor-alpha (TNF-α) plays a central role in inflammation and autoimmune pathology, making it a key therapeutic target. This study systematically evaluated the performance of monoclonal anti-human TNF-α antibodies derived ...