The detection of pro-inflammatory cytokines in exudates from dental pulp tissues [0.03%]
牙髓组织渗出物中促炎细胞因子的检测
Qianqian Wu,Shanshan Li,Ran Li et al.
Qianqian Wu et al.
Background: This research aims to quantify pro-inflammatory cytokines from the exudates of dental pulp tissues are helpful in the diagnosis of pulpitis, thus, laying down the foundation for further vital pulp therapy on i...
Interleukin-17 as a predictor of subclinical synovitis in the remission state of rheumatoid arthritis [0.03%]
IL-17预测风湿关节炎缓解期隐匿性滑膜炎症的价值研究
Sanchaita Misra,Sumantro Mondal,Sulagna Chatterjee et al.
Sanchaita Misra et al.
Objectives: To compare the level of pro and anti-inflammatory cytokines, and angiogenic mediators between Rheumatoid arthritis (RA) patients with and without subclinical synovitis (SS) in remission state, to find the corr...
LncRNA NORAD deficiency alleviates kidney injury in mice and decreases the inflammatory response and apoptosis of lipopolysaccharide-stimulated HK-2 cells via the miR-577/GOLPH3 axis [0.03%]
长链非编码RNA NORAD通过miR-577/GOLPH3轴缓解脂多糖诱导的肾损伤及炎症反应和凋亡缺陷
Zhijuan Xie,Lanji Wei,Jianying Chen et al.
Zhijuan Xie et al.
Background: Long noncoding RNAs (lncRNAs) are significant regulators for sepsis-associated acute kidney injury (AKI). Noncoding RNA activated by DNA damage (NORAD) is highly expressed in the serum of patients with neonata...
HuR confers IL-17a-induced migration and invasion of gastric cancer cells via upregulation of Snail translation [0.03%]
通过上调Snail翻译介导胃癌细胞迁移和侵袭的HuR的作用
Ning Liu,Fan Jiang,Mulin Ye et al.
Ning Liu et al.
Human gastric cancer is a leading cause of cancer mortality in the world wide. We found that the expression of IL-17a was significantly increased in gastric cancer cells. Treatment with recombinant IL-17a (rIL-17a) can increase migration, i...
Low expression of hypoxia-inducible factor-1α and differential expression of immune mediators during experimental infection with Leishmania (Viannia) spp [0.03%]
低表达的缺氧诱导因子-1α和在实验性Leishmania(Viannia)感染过程中免疫介质的差异表达
Camila Alves Mota,Daniele Stéfanie Sara Lopes Lera-Nonose,Aline Ávila Brustolin et al.
Camila Alves Mota et al.
Leishmania (Viannia) species are the major agents of cutaneous leishmaniasis (CL) in the Americas. Ulcerative stigmatizing skin lesions generally characterize CL. The microenvironment during Leishmania infection is rich in inflammatory cell...
Kouji Matsushima,De Yang,Joost J Oppenheim
Kouji Matsushima
Early in the 1980s several laboratories mistakenly reported that partially purified interleukin-1 (IL-1) was chemotactic for neutrophils. However, further investigations by us, revealed that our purified IL-1 did not have neutrophil chemota...
Moxibustion regulates the polarization of macrophages through the IL-4/STAT6 pathway in rheumatoid arthritis [0.03%]
温针调节风湿性关节炎状态下巨噬细胞极化的机制研究
Yu-Mei Zhong,Lin-Lin Zhang,Wen-Ting Lu et al.
Yu-Mei Zhong et al.
Objective: To observe the effects of moxibustion on "Shenshu" and "Zusanli" on macrophage polarization and IL-4/STAT6 signaling pathway in rats with rheumatoid arthritis (RA). To further explore the possible anti-inflamma...
Dennis M de Graaf,Lisa U Teufel,Leo A B Joosten et al.
Dennis M de Graaf et al.
The prognostic significance of serum interferon-gamma (IFN-γ) in hormonally dependent breast cancer [0.03%]
激素依赖型乳腺癌患者血清干扰素γ的预后意义分析
Nataša Todorović-Raković,Jelena Milovanović,John Greenman et al.
Nataša Todorović-Raković et al.
Background: Interferon-γ (IFN-γ) is a pleiotropic immunomodulatory cytokine. Because of its contradictory and even dualistic roles in malignancies, its potential as a biomarker remains to be unraveled. ...
Leptin-mediated proinflammatory bone marrow environment in acquired aplastic anemia [0.03%]
获得性再生障碍性贫血中的瘦素介导的骨髓内炎症微环境
Mengying Gao,Meili Ge,Jiali Huo et al.
Mengying Gao et al.
Acquired aplastic anemia (AA), a paradigm of bone marrow failure syndrome, is mainly caused by abnormal immune activation. The enhanced adipogenesis of bone marrow-derived mesenchymal stem cell (BM-MSC) results in a fatty marrow of AA. Lept...