Increased salivary levels of TNF-α and IL-10 in patients with Crohn's disease [0.03%]
克罗恩病患者的唾液TNF-α和IL-10水平升高
Fernanda Brito,Millena Cobra,Heloisa Fernandes Queiroz Curcio et al.
Fernanda Brito et al.
Background and objective: Salivary cytokines can provide information about oral health and systemic diseases. We aimed to assess the salivary concentration of inflammatory cytokines in outpatients with Crohn's disease (CD...
Translational perspectives of next-generation cytokine therapies for musculoskeletal disorders [0.03%]
下一代细胞因子治疗肌肉骨骼疾病的转化视角
Alexander Kalinkovich,Gregory Livshits
Alexander Kalinkovich
Musculoskeletal disorders (MSDs) are a leading cause of chronic pain and disability worldwide, yet available pharmacological treatments remain largely ineffective or palliative. Increasing evidence indicates that chronic inflammation in MSD...
Association of the T-786C polymorphism of the nitric oxide synthase 3 gene with acute coronary syndrome or premature coronary artery disease: A systematic review and meta-analysis [0.03%]
一氧化氮合酶基因T-786C多态性与急性冠脉综合征或早发冠心病的关联：系统评价和meta分析
Himanshu Rai,J J Coughlan,Daniel O&#x;Callaghan et al.
Himanshu Rai et al.
A systematic review and a study level meta-analysis was conducted to assess the association between the T-786C polymorphism of the nitric oxide synthase 3 (NOS3) gene with acute coronary syndrome (ACS) or premature coronary artery disease (...
The IL-23/IL-17Axis in cutaneous verrucae: evidence from serum cytokine analysis in HPV infection [0.03%]
人乳头瘤病毒感染中银屑病的IL-23/IL-17轴：来源于血清细胞因子分析的证据
Harun Yildirim,Savas Ozturk,Hakan Ayyildiz et al.
Harun Yildirim et al.
Background: Cutaneous verrucae (warts) are benign epidermal proliferations caused by human papillomavirus (HPV) infection. The host immune response particularly T helper 17 (Th17) related cytokines such as interleukin-17A...
Maternal and early-life longitudinal cytokine profiles in a South African birth cohort: the impact of HIV [0.03%]
南非出生队列中母亲和生命早期细胞因子纵向谱型：HIV的影响
Tusekile S Kangwa,Catherine J Wedderburn,Jenna F Annandale et al.
Tusekile S Kangwa et al.
Introduction: During pregnancy, exposure to maternal HIV and a disrupted cytokine environment may impact foetal immune development and health outcomes through cytokine-mediated mechanisms. We evaluated (i) peripheral bloo...
Development of a cholera toxin B subunit-adjuvanted Helicobacter pylori multi-epitope vaccine and evaluation of its immunization effect in mice [0.03%]
development of a cholera toxin b subunit-adjuvanted helicobacter pylori multi-epitope vaccine and evaluation of its immunization effect in mice
Ke Liang,Shuang Wu,Sihang Dong et al.
Ke Liang et al.
This study used epitope screening technology to identify dominant T/B cell epitopes from the Helicobacter pylori virulence factors UreB, CagA, VacA and HpaA, (UCVH) and develop an effective vaccine. These epitopes were fused in series with ...
Adipose tissue macrophages in metabolic inflammation and disease: Insights from single-cell and multi-omics studies [0.03%]
单细胞和多组学研究揭示代谢性炎症和疾病中脂肪组织巨噬细胞的作用
Qining Huang,Jingwen Tang,Xiaozheng Shu et al.
Qining Huang et al.
Adipose tissue macrophages (ATMs) have emerged as central regulators at the interface of immunity and metabolism. Accumulating evidence indicates that ATMs play multifaceted roles in the initiation and progression of obesity-associated meta...
Th1/Th2 cytokine imbalance with novel IL-17F elevation in Iraqi transfusion-dependent beta-thalassemia: a dual-platform diagnostic study [0.03%]
伊拉克输血依赖性β地中海贫血患者中新型的白细胞介素-17F升高及辅助平台的诊断研究
Suzan Sabbar Mutlag,Ghaith A Al-Tameemi,Mohammed Abdul-Mounther Othman
Suzan Sabbar Mutlag
Background: Beta-thalassemia (β-Thal) is an inherited hemoglobin disorder caused by defective β-globin synthesis, resulting in ineffective erythropoiesis, chronic hemolytic anemia, and altered iron metabolism; it is hig...
The significance of vascular endothelial growth factor and systemic inflammatory reaction in bladder cancer patients [0.03%]
血管内皮生长因子和全身性炎症反应在膀胱癌中的意义分析
Zofia Strojny,Dominika Kanikowska,Alina Kanikowska et al.
Zofia Strojny et al.
Bladder cancer (BCa) is the most frequently diagnosed malignancy of the urinary system and is characterized by a multifactorial etiology. Multiple growth factors have been implicated in BCa progression. This cross-sectional study investigat...
Caffeic acid attenuates stress-induced colon inflammation and barrier disruption in Sprague-Dawley rats [0.03%]
咖啡酸通过减轻大鼠结肠炎症和屏障功能障碍从而缓解压力诱导的肠易激综合征症状
Sangita Mazumder,Itishree Dubey,Arushi Gupta et al.
Sangita Mazumder et al.
Chronic stress promotes colonic inflammation by sustaining activation of the hypothalamic-pituitary-adrenal (HPA) axis, inducing oxidative stress, and disrupting barrier integrity, thereby exacerbating inflammatory bowel disease and irritab...