Increased progranulin as an independent predictive biomarker for poor prognosis in sepsis [0.03%]
增高的progranulin作为预测脓毒症不良预后的独立生物标志物
Yi Shan,Xiaoli Zhang,Guanghui Zhou et al.
Yi Shan et al.
Background: Recently, many diagnostic biomarkers were reported, but each had its own limitation. However, there is a need for an effective sensitivity and specificity of biomarker in diagnosis and prognosis of sepsis. In ...
IL-6 dependent expansion of inflammatory MDSCs (CD11b+ Gr-1+) promote Th-17 mediated immune response during experimental cerebral malaria [0.03%]
依赖于IL-6的炎症MDSCs(CD11b+Gr-1+)在实验性脑疟疾中促进Th-17介导的免疫应答中的扩张
Saikat Mukherjee,Soubhik Ghosh,Anirban Sengupta et al.
Saikat Mukherjee et al.
Myeloid derived suppressor cells (MDSCs) are a group of heterogeneous cell populations that can suppress T cell responses. Various aspects of MDSCs in regulating immune responses in several cancer and infectious diseases have been reported ...
Borrelia burgdorferi is strong inducer of IFN-γ production by human primary NK cells [0.03%]
Borrelia burgdorferi能强力诱导人类初始NK细胞产生IFN-γ
Marije Oosting,Michelle Brouwer,Hedwig D Vrijmoeth et al.
Marije Oosting et al.
Natural Killer (NK) cells belong to the innate lymphoid lineage and are highly present in the human skin. NK cells can produce a range of pro-inflammatory mediators, including cytokines and chemokines. The role of NK(-T) cells in the immune...
IL12B rs6887695 polymorphism and interaction with alcohol intake in the risk of ulcerative colitis in Japan [0.03%]
日本IL12Brs6887695多态性与饮酒交互作用增加溃疡性结肠炎风险研究
Yoshihiro Miyake,Keiko Tanaka,Chisato Nagata et al.
Yoshihiro Miyake et al.
Background: The interleukin (IL)-23/Th17 pathway plays a critical role in ulcerative colitis (UC). The IL-12p40 subunit, which is shared by IL-23 and IL-12, is encoded by the IL12B gene. The current case-control study inv...
Study on diagnostic value of results of EB virus nucleic acid quantification in whole blood lymphocyte and serum in children with EB virus infection [0.03%]
检测外周血淋巴细胞和血清EB病毒核酸拷贝数的诊断价值研究
Weian Gao,Jinhua Wu,Yiyao Han et al.
Weian Gao et al.
Background: The article aims to study the results of EB virus nucleic acid quantification (EBV-DNA) in whole blood lymphocytes to examine whether serum can diagnose EB virus infection in children. Group A consisted of 65 ...
Corrigendum to "Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP)" [Cytokine 125 (2020) 154853] [0.03%]
关于“白细胞介素-37减轻炎症并损害免疫性血小板减少症（ITP）中的血小板吞噬作用”[细胞因子125（2020）154853]的勘误表
Yajing Zhao,Xiaofei Ni,Pengcheng Xu et al.
Yajing Zhao et al.
Published Erratum
Cytokine. 2022 Jul:155:155900. DOI:10.1016/j.cyto.2022.155900 2022
High occurrence of CRLF2 abnormalities in Mexican children with B-cell acute lymphoblastic leukemia [0.03%]
墨西哥儿童B细胞急性淋巴细胞白血病中CRLF2异常的发生率较高
María Del Rocío Juárez-Velázquez,Dafné Linda Moreno-Lorenzana,Daniel Alejandro Martínez Anaya et al.
María Del Rocío Juárez-Velázquez et al.
The P2RY8-CRLF2 and IGH-CRLF2 rearrangements induce the overexpression of cytokine receptor-like factor 2 (CRLF2) and have been associated with relapse and poor prognosis in B-cell acute lymphoblastic leukemia (B-ALL). Additionally, they ar...
MicroRNA-23a-3p ameliorates acute kidney injury by targeting FKBP5 and NF-κB signaling in sepsis [0.03%]
microRNA-23a-3p通过靶向FKBP5和NF-κB信号通路缓解脓毒症急性肾损伤
Hui Xu,Zenggeng Wang
Hui Xu
Low miR-23a-3p expression in patients with acute kidney injury (AKI) or sepsis has been revealed. However, the specific role of miR-23a-3p in AKI remains unclear. Our study aimed to determine the function of miR-23a-3p in AKI. Exposure to l...
IL-36G promotes cancer-cell intrinsic hallmarks in human gastric cancer cells [0.03%]
人胃癌细胞中IL-36G促进癌症细胞固有的标志物表达
Ngan Le,Ian Luk,David Chisanga et al.
Ngan Le et al.
Interleukin-36 gamma (IL-36G) is a member of the IL-36 subfamily of cytokines and acts as a potent driver of inflammation. IL-36G has been extensively characterized in the pathogenesis of psoriasis and has been recently described to play ro...
Pirfenidone mitigates TGF-β1-mediated fibrosis in an idiopathic inflammatory myositis-associated interstitial lung disease model [0.03%]
吡非尼酮通过建立特发性炎性肌炎相关间质性肺病模型缓解TGF-β1介导的纤维化作用
Habib Layoun,Joelle Hajal,Youakim Saliba et al.
Habib Layoun et al.
Idiopathic inflammatory myositis (IIM) is a group of rare diseases of unknown etiology, with a pathognomonic muscular deficiency. Antisynthetase syndrome is a subtype of IIM with an associated interstitial lung disease (ILD), characterized ...