Identification of duck GSDME: Tissue distribution, proteolysis and cellular location [0.03%]
鹅GSDME的鉴定：组织分布、蛋白水解及其细胞定位
Yao Cheng,Shun Chen,Bowen Jiang et al.
Yao Cheng et al.
Gasdermin E (GSDME) is a member of the gasdermin family. Cleavage of mammalian GSDME by apoptotic caspases or granzyme proteases liberates the N-terminal effector domain (GSDME-N), which is capable of forming membrane pores and executing in...
Interferon gamma upregulates the cytokine receptors IFNGR1 and TNFRSF1A in HT-29-MTX E12 cells [0.03%]
干扰素γ通过调节细胞表面受体IFNGR1和TNFRSF1A的表达诱导结肠直肠腺癌细胞系HT-29-MTX E12中的I型主要组织相容性复合体
Brandon Johnson,Paulina Panek,Andy Yu et al.
Brandon Johnson et al.
The intestinal mucosa protects the body from physical damage, pathogens, and antigens. However, inflammatory bowel diseases (IBDs) patients suffer from poor mucosal tissue function, including the lack of an effective cellular and/or mucus b...
The association of cytokine gene polymorphisms with tuberculosis susceptibility in several regional populations [0.03%]
细胞因子基因多态性与几个地区人群结核分枝杆菌易感性的关联分析
Qibin Liu,Xianxiang Chen,Xiyong Dai
Qibin Liu
Purpose: By collecting the data of all relevant articles, the goal of this study was to better understand the relationship between the IL-6/IL-18 polymorphism and susceptibility to tuberculosis in several regional populat...
Meta-Analysis
Cytokine. 2022 Aug:156:155915. DOI:10.1016/j.cyto.2022.155915 2022
Antigens from the parasitic nematode Trichuris suis induce metabolic reprogramming and trained immunity to constrain inflammatory responses in macrophages [0.03%]
猪 whipworm抗原通过代谢重编程和训练免疫限制巨噬细胞的炎症反应
Amin Zakeri,Bart Everts,Andrew R Williams et al.
Amin Zakeri et al.
Regulation of macrophage (Mɸ) function can maintain tissue homeostasis and control inflammation. Parasitic worms (helminths) are potent modulators of host immune and inflammatory responses. They have evolved various strategies to promote i...
Cytokine chemokine network in tumor microenvironment: Impact on CSC properties and therapeutic applications [0.03%]
肿瘤微环境中细胞因子和趋化因子网络对癌症干细胞的影响及治疗应用
Mushtaq Ahmad Nengroo,Ayushi Verma,Dipak Datta
Mushtaq Ahmad Nengroo
A subpopulation of cells in many cancers has stem cell traits, mediates metastasis, and contributes to treatment resistance. These cells are considered as cancer stem cells (CSCs). CSC properties of tumor cells are immensely regulated by cl...
Immunotherapeutic potential of ethanolic olive leaves extract (EOLE) and IL-28B combination therapy in ENU induced animal model of leukemia [0.03%]
ENU诱导的白血病动物模型中橄榄叶乙醇提取物与IL-28B联合免疫治疗的潜力研究
Priyatosh Nath,Debabrata Majumder,Rahul Debnath et al.
Priyatosh Nath et al.
Cytokine therapies have shown promising results against cancers. Cytokines are secreted naturally from different bodily cells. These have fewer side effects but higher specificity than chemotherapy and radiation therapy. In leukemia, change...
Decreased leukocyte exhaustion is associated with decreased IFN-β and increased α-defensin-1 levels in type-2 diabetes [0.03%]
糖尿病患者的免疫细胞衰竭与I型干扰素(IFN-β)水平下降和α-防御素-1(DEFB1)水平升高有关
Sugumar Shruthi,Joy Manohar Sibi,Viswanathan Mohan et al.
Sugumar Shruthi et al.
Pan-leukocyte exhaustion is a physiological process associated with immune homeostasis. Too much of immune exhaustion can lead to immune impairment and increased susceptibility to infections and cancer; too little can lead to chronic inflam...
Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine [0.03%]
白细胞介素33（IL-33）：其生物学及其作为强力分泌性细胞因子的释放机制批判性述评
Corinne Cayrol,Jean-Philippe Girard
Corinne Cayrol
Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic inflammation, viral infection, and cancer. IL-33 is abundant in the ...
LncRNA KCNQ1OT1 knockdown inhibits ox-LDL-induced inflammatory response and oxidative stress in THP-1 macrophages through the miR-137/TNFAIP1 axis [0.03%]
KCNQ1OT1通过miR-137/TNFAIP1轴抑制氧化低密度脂蛋白诱导的THP-1巨噬细胞炎症反应和氧化应激
Can Xu,Lei Chen,Ru-Jing Wang et al.
Can Xu et al.
Both inflammatory response and oxidative stress are regarded as two critical contributors to atherosclerosis. Kcnq1 overlapping transcript 1 (KCNQ1OT1) is an imprinted antisense long non-coding RNA in the kcnq1 locus. Our previous study has...
Marilyn Masih,Sonam Agarwal,Rupinder Kaur et al.
Marilyn Masih et al.
Chemokines belong to a family of chemoattractant cytokines and are well known to have an essential role in various cancer aetiologies. Multiplesubsets of immune cells are recruited and enrolled into the tumor microenvironment through intera...