Necrostatin-1 attenuates Caspase-1-dependent pyroptosis induced by the RIPK1/ZBP1 pathway in ventilator-induced lung injury [0.03%]
Necrostatin-1通过RIPK1/ZBP1途径依赖的Caspase-1减少通气所致肺损伤中pyroptosis的发展
Rong-Ge Shao,Qiu-Wen Xie,Ling-Hui Pan et al.
Rong-Ge Shao et al.
Background: Ventilator-induced lung injury (VILI) is a complex pathophysiological process leading to acute respiratory distress syndrome (ARDS) and poor outcomes in affected patients. As a form of programmed cell death, p...
Meteorin-like protein (Metrnl): A metabolic syndrome biomarker and an exercise mediator [0.03%]
流星素样蛋白（METRNЛ）：代谢综合征的生物标志物和运动的调节因子
Hamid Alizadeh
Hamid Alizadeh
Metrnl is a secreted protein able to activate different intracellular signaling pathways in adipocytes, macrophages, myocytes and cardiomyocytes with physiological effects of the browning of white adipose tissue (BWT), insulin sensitivity, ...
Ursolic acid represses influenza A virus-triggered inflammation and oxidative stress in A549 cells by modulating the miR-34c-5p/TLR5 axis [0.03%]
乌索酸通过调节miR-34c-5p/TLR5轴抑制尿囊炎病毒诱导的炎症和氧化应激
Xing Wei,Yuying Lan,Zhifei Nong et al.
Xing Wei et al.
Background: Ursolic acid (UA) is a pentacyclic triterpenoid compound with a wide range of anti-tumor, anti-inflammatory, hypotensive and other pharmacological effects. Here, the biological roles and regulatory mechanisms ...
Differential cytokine profiles produced by anti-epileptic drug re-exposure of peripheral blood mononuclear cells derived from severe anti-epileptic drug patients and non-allergic controls [0.03%]
卡马西平过敏重症患者与非过敏对照者外周血单个核细胞对多种抗癫痫药物再刺激产生不同的细胞因子谱式
Yuttana Srinoulprasert,Pongsathorn Kumkamthornkul,Papapit Tuchinda et al.
Yuttana Srinoulprasert et al.
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and drug reactions with eosinophilia and systemic symptoms (DRESS) are the most common severe cutaneous adverse drug reactions (SCARs). Anti-epileptic drugs are one of the most c...
Saga of monokines in shaping tumour-immune microenvironment: Origin to execution [0.03%]
单核因子在塑造肿瘤免疫微环境中的作用：从起源到执行
Naveen Challagundla,Dhruvi Shah,Shivani Yadav et al.
Naveen Challagundla et al.
Cellular communication mediated by cytokines is an important mechanism dictating immune responses, their cross talk and final immune output. Cytokines play a major role in dictating the immune outcome to cancer by regulating the events of d...
Protective effects of intranasal curcumin on silica-induced lung damage [0.03%]
姜黄素鼻腔给药对硅尘致小鼠肺损伤的保护作用研究
Sneha Kumari,Rashmi Singh
Sneha Kumari
Objective: Being anti-inflammatory and an antioxidant in nature, curcumin has been studied for its anti-asthmatic effects, but its impact on silicosis has not been investigated before. It is a form of occupational lung il...
IL-1 family cytokines serve as 'activity recognition receptors' for aberrant protease activity indicative of danger [0.03%]
白细胞介素-1家族细胞因子作为异常蛋白酶活性指示危险信号的“活性识别受体”发挥作用
Seamus J Martin,Valentina Frezza,Pavel Davidovich et al.
Seamus J Martin et al.
Members of the extended IL-1 cytokine family play key roles as instigators of inflammation in numerous infectious and sterile injury contexts and are highly enriched at barrier surfaces such as the skin, lungs and intestinal mucosa. Because...
Factors affecting the induction of uncoupling protein 1 in C2C12 myogenic cells [0.03%]
影响UCP1在C2C12肌细胞中诱导的因素
Takehiro Yamamoto,Zhicheng Diao,Masaru Murakami et al.
Takehiro Yamamoto et al.
Brown/beige adipocytes, which are derived from skeletal muscle/smooth muscle-lineage cells, consume excess energy as heat through the expression of mitochondrial uncoupling protein 1 (UCP1). Previous studies have shown that forced expressio...
The expression of TNF-α in recurrent aphthous stomatitis: A systematic review and meta-analysis [0.03%]
复发性阿弗他溃疡中TNF-α的表达：系统评价和Meta分析
Meircurius Dwi Condro Surboyo,Rizky Merdietio Boedi,Ninuk Hariyani et al.
Meircurius Dwi Condro Surboyo et al.
Objective: The pathogenesis of recurrent aphthous stomatitis (RAS) is related to an increase of pro-inflammatory cytokine, namely tumor necrosis factor α (TNF-α). This cytokine plays an important role in the development...
Impact of cytokines genes polymorphisms and their serum levels on childhood asthma in Egyptian population [0.03%]
细胞因子基因多态性及其血清水平对埃及儿童哮喘的影响研究
Amal S El-Shal,Sally M Shalaby,Hanim M Abdel-Nour et al.
Amal S El-Shal et al.
Background: Asthma is chronic immune-mediated airway inflammation, and it is affected by a complex network of interacting cytokines. To date, the exact role of each cytokine and its genetic polymorphisms in childhood asth...