Interplay between growth factor signaling and epigenetic landscapes in stem cell stemness [0.03%]
生长因子信号与干细胞干性表观遗传景观间的相互作用
Sananda Kumar Patra,Dhiraj Gurjar,Bhaskar Saha et al.
Sananda Kumar Patra et al.
Growth factors and cytokines are fundamental regulators of stem cell fate, controlling both self-renewal and differentiation across the embryonic hierarchy. ESCs that originate from the ICM of the blastocyst can self-renew indefinitely and ...
The multifaceted role of acetamide derivative of chalcone: Anti-inflammatory action and impact on osteoclastogenesis, insights on NF-κB and MAPK pathway [0.03%]
醋胺衍生物的多功能作用：抗炎作用和对破骨细胞生成的影响，关于NF-κB和MAPK途径的见解
Sobia Anjum,Tazeem Akram,Unnatti Sharma et al.
Sobia Anjum et al.
Inflammation is a crucial physiological response that maintains tissue homeostasis and protects against various diseases. However, in autoimmune disorders like rheumatoid arthritis (RA), chronic inflammation promotes osteoclastogenesis and ...
Icariin alleviates ovariectomy-induced osteoporosis by promoting M2 macrophage polarization and suppressing osteoclast activation [0.03%]
淫羊藿黄酮/icaritin通过促进M2型巨噬细胞极化和抑制破骨细胞活化治疗卵巢切除诱导的骨质疏松症
Yongdong Yang,Chuan Luo,Xingyu Ren et al.
Yongdong Yang et al.
Background: Osteoporosis is a prevalent skeletal disorder marked by reduced bone strength and increased fragility, especially in postmenopausal women and older adults. Icariin (ICA), a natural flavonoid, has been reported...
Single-cell profiling of the immune landscape at the maternal-fetal interface in unexplained recurrent miscarriage [0.03%]
不明原因反复流产妊娠滋养细胞及免疫微环境的单细胞转录组分析
Wu Huimei,Yu Zhaoyang,Wang Xinwei et al.
Wu Huimei et al.
This study uses single-cell RNA sequencing (scRNA-seq) profiling to explore the heterogeneity of CD4+ T cells at the maternal-fetal interface in URM and normal pregnancy groups, and to investigate the cell subsets associated with URM and th...
EGFR as a context-dependent modulator of endothelial inflammation: A systematic review [0.03%]
EGFR在不同条件下的内皮炎症调节作用：系统综述
Giulia Maria Giacinti,Lorena Souza Castro Altoé,Adriana Madeira Álvares da Silva et al.
Giulia Maria Giacinti et al.
Epidermal growth factor receptor (EGFR), a member of the ErbB family, regulates key cellular processes such as proliferation, survival, and differentiation, and participates in angiogenesis and pathological conditions, including cancer; how...
Harnessing the Power of IL-12: Revolutionizing Cancer Therapy with Combinatorial Strategies [0.03%]
利用IL-12的力量：用组合策略革新癌症治疗
Yuxi Zhang,Jing Tian,Wen Cheng et al.
Yuxi Zhang et al.
Interleukin-12 (IL-12) is a potent immunostimulatory cytokine that enhances T cell and natural killer (NK) cell activation and promotes Th1-type immune responses. However, its clinical application as monotherapy has been hampered by systemi...
Corrigendum to "CCL17 and CCL19 are markers of disease progression in alveolar echinococcosis" [Cytokine 181 (2024) 156669] [0.03%]
“CCL17和CCL19是泡型棘球蚴病进展的标志物”一文中的一处勘误[Cytokine 181 (2024) 156669]
Jiahui Chen,Yuyu Ma,Yumei Liu et al.
Jiahui Chen et al.
Published Erratum
Cytokine. 2026 Jun 12:157178. DOI:10.1016/j.cyto.2026.157178 2026
Efficacy and safety of IgG-pathway inhibitors in adult immune thrombocytopenia: A systematic review and meta-analysis with subgroup analyses of FcRn and SYK inhibitors [0.03%]
免疫球蛋白G通路抑制剂治疗成人免疫性血小板减少症的有效性和安全性：系统评价和-meta分析及FcRn和SYK抑制剂的亚组分析
Mousa Almasalma,Ahmed Hamdy Kandil,Mahmoud Hashem Al-Qadi et al.
Mousa Almasalma et al.
Background: Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by platelet counts
Innovative immune checkpoint modulators: monoclonal antibodies, small molecules, non-coding RNAs, and nanoparticles in cancer immunotherapy [0.03%]
创新的免疫检查点调节剂：用于癌症免疫治疗的单克隆抗体、小分子、非编码RNA和纳米粒子
Sevda Jafari,Habib Zarredar,Alireza Ostadrahimi et al.
Sevda Jafari et al.
Targeting immune checkpoints through diverse therapeutic platforms has emerged as a promising strategy for cancer immunotherapy, offering improved outcomes compared with conventional chemotherapy. Immune checkpoint pathways are critical reg...
Progranulin as a context-dependent regulator of innate immunity in bacterial infections [0.03%]
蛋白原粒素在细菌感染中作为调控先天免疫的环境依赖因子
Camelia Félix-Arellano,Cesar Rivas-Santiago,Eva Salinas et al.
Camelia Félix-Arellano et al.
The outcome of bacterial infections depends on a delicate balance between effective pathogen clearance and the containment of immune-mediated damage. Disruption of this equilibrium promotes both microbial persistence and immunopathology, a ...