CiATG13 induces autophagy to regulate CiHSP70 to promote GCRV replication [0.03%]
CiATG13通过诱导自噬调节CiHSP70来促进GCRV的复制
Yanxia Jiang,Li Wu,Yingqi Gao et al.
Yanxia Jiang et al.
Ctenopharyngodon idella (grass carp) is the dominant species in freshwater aquaculture, but its farming industry is severely threatened by grass carp haemorrhagic disease (GCHD) caused by grass carp reovirus (GCRV). Autophagy plays a crucia...
Antibacterial mechanisms of magnolol against Streptococcus agalactiae and immunomodulatory effects in Schizothorax prenanti [0.03%]
Magnolol的抗菌机制及其在西藏裸鲤体内的免疫调节效应研究
Yilin Wang,Kun Peng,Longjun Deng et al.
Yilin Wang et al.
Streptococcus agalactiae is an important zoonotic pathogen with an expanding host range and increasing antibiotic resistance, presenting a significant risk to the aquaculture in China. Therefore, developing effective treatment approaches an...
Exploring hemopexin's antibacterial activity in bony fish: An immunological study of PoHpx-a [0.03%]
骨鱼血红素结合蛋白PoHpx-a的抗菌活性研究
Sheng-Han Gao,Yi-Qi Zhou,Wen Du et al.
Sheng-Han Gao et al.
Hemopexin (Hpx) is a conserved acute-phase protein that participates in the immune regulation and anti-bacterial response of higher vertebrates. However, the immunological function of Hpx in bony fish remains largely unclear. In this study,...
2,6-Dibromophenol inhibits fin regeneration in zebrafish larvae via Wnt-mediated immune cell recruitment [0.03%]
2,6-二溴苯酚通过Wnt介导的免疫细胞募集抑制斑马鱼幼体的鳍再生
Yuhan Huang,Wenya Tie,Zijian Li et al.
Yuhan Huang et al.
2,6-Dibromophenol (2,6-DBP), a typical brominated phenolic disinfection byproduct, is frequently detected in drinking water after disinfection. However, its effect on tissue regeneration has not been previously reported. In this study, usin...
Cooperative roles of Pm-RORα splice variants in modulating the immune response in the pearl oyster P. f. martensii [0.03%]
三角帆文蛤(Pinna ficus martensii)中Pm-RORα拼接变异体在免疫应答中的协同作用
Zhihao Chen,Xueru Liang,Guixuan Chen et al.
Zhihao Chen et al.
RAR-related orphan receptor alpha (RORα), a core member of the NR1F subgroup within the nuclear receptor superfamily, critically regulates lipid metabolism and immune responses. This study identified the Pm-RORα (Pm-RORα1 and Pm-RORα2) ...
Toll-like receptor 2 (TLR2) functions as a key regulator of inflammatory responses to Vibrio parahaemolyticus infection in the Manila clam (Ruditapes philippinarum) [0.03%]
toll-like受体2(tlr2)通过调节副溶血性弧菌感染的魁阁蛤(ruditapes philippinarum)炎症反应发挥作用
Jiaxin Liang,Tian Yu,Haodong Feng et al.
Jiaxin Liang et al.
Toll-like receptor 2 (TLR2) is a pivotal pattern-recognition receptor in innate immunity. It is well characterized in vertebrates but remains poorly understood in mollusks. In this study, we identified a TLR2 homolog (RpTLR2) in Ruditapes p...
Identification of two MAPK transcripts in the colonial ascidian Botryllus schlosseri: involvement in immune and stress responses and potential roles in colony growth [0.03%]
两个MAPK转录子在群居索藻Botryllus schlosseri中的鉴定：对免疫和压力响应的参与及可能对群体生长的作用
Laura Drago,Francesca Frisoni,Gianfranco Santovito et al.
Laura Drago et al.
Mitogen-activated protein kinase (MAPK) pathways are evolutionarily conserved signalling cascades that regulate fundamental cellular processes such as proliferation, differentiation, and stress responses. In the colonial ascidian Botryllus ...
Evolution and functional diversification of CDK genes in bivalves: insights from Chlamys nobilis under biotic and abiotic stresses [0.03%]
双壳类动物CDK基因的进化与功能多样化：来自受生物和非生物胁迫影响下的冠蚌的见解
Zeyang Zheng,Ziru Huang,Shitong Liu et al.
Zeyang Zheng et al.
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and transcriptional control, and play critical roles in stress responses. However, systematic studies and functional characterizations of the CDK gene family in bi...
Newly identified TRAF7 interacts with TAK1 and regulates immune response in Chlamys farreri [0.03%]
新型TRAF7与TAK1互作并调控栉孔扇贝免疫反应
Xiaoxue Lin,Zihao Zhang,Xiaolong Chu et al.
Xiaoxue Lin et al.
Tumor necrosis factor receptor-associated factor 7 (TRAF7) is an atypical member of the TRAF family, with well-established roles in modulating vertebrate innate immunity, apoptosis, and intracellular signal transduction. In contrast, its fu...
Molecular cloning and functional characterization of PIASx from Epinephelus coioides reveals its negative regulatory role in antiviral immunity [0.03%]
石斑鱼PIASx的分子克隆及功能表征揭示其在抗病毒免疫中的负调节作用
Shaozhu Kang,Qiongyue Xu,Xiaohui Zheng et al.
Shaozhu Kang et al.
The protein inhibitor of activated signal transduction and transcription activation (STAT) (PIAS) family is a key class of signal transduction modulators that regulate innate immune signaling pathways activated by transcription factors incl...