Antibacterial activity and mechanism of a crab-derived i-type lysozyme against multidrug-resistant Vibrio alginolyticus [0.03%]
一种蟹源I型溶菌酶对耐多药发光 vibrio 的抗菌活性及机制研究
Yi Zhang,Ke Xu,Yijing Wu et al.
Yi Zhang et al.
The emergence and rapid spread of multidrug-resistant bacteria in aquaculture environments threatens the healthy development of the aquaculture industry and public health, driving demand for novel antimicrobial agents as alternatives to ant...
Structural and functional analysis of hemocyanin from freshwater crab Barytelphusa cunicularis (Westwood in Sykes, 1836) exhibiting dual enzymatic functions [0.03%]
具有双重酶功能的淡水蟹Barytelphusa cunicularis (Westwood in Sykes，1836)血蓝蛋白的结构和功能分析
Sundararajan Sowmiya,Rangasamy Shanthi,Mullaivanam Ramasamy Sivakumar
Sundararajan Sowmiya
Although hemocyanin is a major oxygen-transport protein in crustaceans, its structural and functional diversity in freshwater crabs remains poorly understood. In this study, hemocyanin from the serum of Barytelphusa cunicularis was isolated...
Genome-wide identification of the collectin family in silver pomfret (Pampus argenteus) and innate immune functions of a novel truncated member PaCL-11b against Vibrio parahaemolyticus [0.03%]
牙鲆 Collectin 家族的基因组鉴定及新型截短成员PaCL-11b抗溶藻弧菌的固有免疫功能
Wenxiaoman Wang,Mengmeng Xu,Yadong Xue et al.
Wenxiaoman Wang et al.
The Collectin family, an important member of the C-type lectin superfamily, participates in innate immune defense through Ca2+-dependent recognition of glycan ligands on pathogen surfaces. In this study, five Collectin family members were i...
Effects of temperature and Nocardia crassostreae on the immune response of the Pacific oyster, Magallana gigas [0.03%]
温度及迟缓爱德华氏菌对太平洋牡蛎（Crassostrea gigas Thunberg）免疫应答的影响
George Mason,Christopher Dwane,Luke A Holmes et al.
George Mason et al.
Summer mortality events continue to threaten Pacific oyster (Magallana gigas) production worldwide, having consequences for local economies and food security, yet the physiological mechanisms underlying these losses remain poorly resolved, ...
Identification and functional characterization of type II interferon receptors (CRFB6, CRFB13 and CRFB17) in Japanese eel (Anguilla japonica) [0.03%]
日本鳗鱼II型干扰素受体(CRFB6、CRFB13和CRFB17)的鉴定及功能分析
Shengnan Su,Changji Lin,Zhanzhuang Zeng et al.
Shengnan Su et al.
In mammals, IFN-γ acts as a critical cytokine that triggers intracellular signaling by binding to specific IFNGR1 and IFNGR2 receptors. Unlike mammals, teleosts possess two members of type II IFN genes (IFN-γ and IFN-γrel), two IFNGR1 pa...
Functional characterization of an IRF7 homologue in large yellow croaker (Larimichthys crocea) [0.03%]
大黄鱼(Larimichthys crocea)IRF7同源基因的功能表征
Wenxing Li,Yuan Feng,Jiamei Liu et al.
Wenxing Li et al.
Interferon regulatory factor 7 (IRF7) functions as a central orchestrator of type I interferon (IFN) responses in mammals, yet the functional mechanisms of its homologue in teleost remains incompletely understood. Here, we characterized an ...
Establishment of a novel brain cell line from grass carp (Ctenopharyngodon idella) with high transfection efficiency and CRISPR/Cas9-mediated genome editing capacity [0.03%]
一种新型高效转染和CRISPR/Cas9基因编辑草鱼脑细胞系的建立
Zi-Ling Qu,Tao Liu,Tang-Kai-Yuan Qin et al.
Zi-Ling Qu et al.
Fish cell lines serve as valuable tools in aquaculture research, particularly in immunology, pathology, and toxicology. In this study, we successfully established a novel cell line derived from brain tissue of grass carp, designated CIB. Th...
Cepharanthine suppresses LMBV replication via cell cycle arrest and immunomodulation [0.03%]
喜树碱抑制LMBV复制通过细胞周期阻滞和免疫调节作用
Bowen Liu,Mengmeng Wang,Zheming Zhang et al.
Bowen Liu et al.
In recent years, the viral disease caused by largemouth bass virus (LMBV) has inflicted severe economic losses on China's largemouth bass (Micropterus salmoides) aquaculture, significantly restricting its development. As targeted antiviral ...
Caffeic acid phenethyl ester induces healthy expansion of adipose tissue and protects against Aeromonas hydrophila infection via p65-dicentracin pathway in high-carbohydrate diet-fed largemouth bass (Micropterus salmoides) [0.03%]
咖啡酸苯乙酯通过p65-双色花内酯途径诱导高碳水化合物饮食下健鲤(Micropterus salmoides)脂肪组织的健康扩张并抵抗 Aeromonas hydrophila 感染
Jie Li,Yi Wang,Chang Liu et al.
Jie Li et al.
High-carbohydrate diet (HCD) is widely used in aquaculture to reduce protein costs, but it often induces pathological adipose tissue hypertrophy, chronic inflammation, and increased susceptibility to bacterial infections. This study investi...
Shrimp TM9SF4 facilitates WSSV infection probably through interacting with viral VP24 and regulating host autophagy [0.03%]
虾TM9SF4通过与病毒VP24相互作用和调节宿主自噬来促进对WSSV的感染
Aixin Li,Shihao Li,Zhanyuan Yang et al.
Aixin Li et al.
Autophagy is a highly conserved cellular process that plays a dual role during viral infection, contributing to antiviral defense while also being exploited by viruses to support their replication. However, the molecular mechanisms by which...