Gut microbiota dysbiosis triggered by salinity stress enhances systemic inflammation in spotted scat (Scatophagus argus) [0.03%]
盐度胁迫引起的肠道微生物群失调增强月鱼（斑马拟丽鱼）的全身炎症反应
Yuan Sun,Jiajia Wu,Huixue Li et al.
Yuan Sun et al.
As an ecological disturbance, salinity changes substantially impact aquatic organism health. Gut microbiota plays a pivotal role in host health and exhibits heightened sensitivity to environmental salinity stress; however, the potential cor...
Seventy years of coexistence: Parasites and Mediterranean fish aquaculture [0.03%]
七十年的共生关系：鱼类寄生虫与地中海水产养殖业
Ivona Mladineo,Jerko Hrabar
Ivona Mladineo
What can be regarded as a seedling of the contemporary aquaculture in the Mediterranean began back in the 1950s. The development of the industry did not always align with the development of ichthyopathology, a veterinary discipline aimed at...
Establishment of mud crab (Scylla paramamosain) spermatogonial stem cell line: A potential tool for immunological research [0.03%]
中华绒螯蟹(S.paramamosain)精原干细胞系的建立——免疫学研究的理想模型细胞系
Ying Song,Yanchuang Duan,Haiqing Luo et al.
Ying Song et al.
Spermatogonial stem cells (SSCs) can differentiate into sperm and are important for studying on genetic information transmission of animals. However, the establishment of the SSC line in crustaceans is still in its infancy. This study aimed...
Enhancement of Reactive Oxygen Species metabolism by antioxidant enzyme Cu/Zn-SOD can block betanodavirus-induced necroptosis and suppress viral replication in fish cells [0.03%]
抗氧化酶Cu/Zn-SOD通过增强活性氧代谢抑制鱼细胞中神经坏死病毒诱导的坏死性凋亡及病毒复制
Hong-Jun Liao,Jiann-Ruey Hong
Hong-Jun Liao
Very little is known about oxidative stress as a modulator of signaling between the host and virus in viral nervous necrosis (VNN) within the aquaculture field. In the present study, we examined whether blocking ROS signaling using mitochon...
Dual protection against grouper Rana-Iridovirus (GIV-R) and nervous necrotic virus (NNV) by novel GIV-R-Δ51-NNV-CP chimeric vaccine candidates [0.03%]
新型GIV-R-Δ51-NNV-CPS复合疫苗候选苗对真鲷蓝舌病病毒（GIV-R）和神经坏死病毒（NNV）的双重保护效果
Shan Ding,Yong Li,Qianqian Sun et al.
Shan Ding et al.
Grouper Rana-iridovirus (GIV-R) and nervous necrosis virus (NNV) are two distinct yet very important causative agents in several fish species. However, as of now, no effective treatment has been developed to simultaneously prevent these two...
Evaluation of immune responses and protection in Asian seabass (Lates calcarifer Bloch, 1790) against Vibrio vulnificus using immersion and oral nanoemulsion vaccines [0.03%]
用于亚洲红笛鲷对光源弧菌的浸浴和口服纳米乳佐剂疫苗诱导免疫应答及保护效果评价
Chatchai Rodwihok,Kim D Thompson,Prapansak Srisapoome et al.
Chatchai Rodwihok et al.
Vaccination is an important strategy in aquaculture for enhancing disease resistance and ensuring the health and productivity of cultured fish. This study investigated the distinct systemic and mucosal immune responses elicited by immersion...
NLRC3 regulates RIP2, STING, TBK1, and TRAF6 mediated type I IFN signaling and inflammatory response in large yellow croaker Larimichthys crocea [0.03%]
NLRC3调控大黄鱼 Larimichthys crocea 中的RIP2、STING、TBK1和TRAF6介导的Ⅰ型干扰素信号通路及炎症反应
Yu Qing Xu,Ying Li,Kun Huang Han et al.
Yu Qing Xu et al.
As a member of the NLRs family, NLRC3 has been determined to function in the NF-κB, MAPK, and type I IFN signaling, which are crucial for the host innate immunity and inflammatory response. In this study, an NLRC3 ortholog, named as Lc-NLR...
Chitooligosaccharide enhances immune response and resistance of oyster Crassostrea gigas against Vibrio splendidus [0.03%]
壳寡糖增强太平洋牡蛎Crassostrea gigas 对灿烂弧菌的免疫应答和抗性
Wentong Hao,Ao Xu,Ning Kong et al.
Wentong Hao et al.
Chitooligosaccharide (COS), an eco-friendly and non-toxic functional oligosaccharide, exhibits immune-enhancing effects on a variety of aquatic species. In the present study, the expression levels of cytokines, phagocytic activity of haemoc...
pIgR-like4.2 enhances the antiviral immune response of zebrafish against spring viremia of carp virus [0.03%]
猪R_like4.2增强鲤春病毒病抗病毒免疫反应
Xiaoyun Chen,Chang Cai,Shuai Li et al.
Xiaoyun Chen et al.
The mucosal immune system plays a critical role in defending the body against external pathogens and preserving homeostasis. The polymeric immunoglobulin receptor (PIGR) is a critical component of this system, responsible for facilitating t...
ZFYVE1 suppresses IRF3/7-mediated antiviral innate immunity in black carp [0.03%]
ZFYVE1抑制草鱼IRF3/7介导的抗病毒天然免疫反应
Zewen Yi,Jiaxin Wang,Shasha Tan et al.
Zewen Yi et al.
Zinc finger FYVE-type containing 1 (ZFYVE1), a FYVE-containing protein, exerts a significant function during autophagosome formation and lipid droplet metabolism. Nevertheless, it is currently unclear whether teleost ZFYVE1 influences antiv...