Dietary supplementation of Lactobacillus casei alleviates permethrin exposure-induced zebrafish testis damage through modulation of TLR4/NF-κB and AKT/Nrf2 pathways: Oxidative stress, inflammation and ferroptosis [0.03%]
枯草芽孢杆菌饮食补充通过调节TLR4/NF-κB和AKT/Nrf2途径缓解联苯菊酯诱导的斑马鱼睾丸损伤：氧化应激，炎症和铁死亡
Yu Huo,Yuhan Wang,Ningna Ma et al.
Yu Huo et al.
The widespread use of permethrin (Per) poses significant risks to aquatic ecosystems, particularly through reproductive toxicity. This study investigated the protective effects of Lactobacillus casei (L. casei) against Per-induced testicula...
Risk assessment and resistant mechanism of Fusarium graminearum to fluopyram [0.03%]
寡雄腐霉对氟吡菌胺的风险评估及其抗性机制分析
Zhang Jie,Sun SiYu,Guo Yu et al.
Zhang Jie et al.
Fusarium head blight (FHB), caused by the Fusarium graminearum species complex, poses a significant threat to global wheat production and human health due to its high virulence and the ability to produce harmful secondary metabolites. Altho...
CRISPR/Cas9 mediated knockout of laccase2 impairs cuticle tanning and pigmentation in the tobacco cutworm, Spodoptera litura [0.03%]
CRISPR/Cas9介导的漆酶2基因敲除影响烟草天蛾幼虫表皮硬化和着色反应
Yingchuan Peng,Yu He,Xinyi Ling et al.
Yingchuan Peng et al.
Cuticle tanning is a vital physiological process in insects, mediated by the phenol oxidase Laccase2 (Lac2). To elucidate the functional role underlying cuticle formation in the economically important pest Spodoptera litura, SlitLac2 was fu...
Characterization of Caenorhabditis elegans transient receptor potential vanilloid (TRPV) channels and their interactions with insecticidal compounds [0.03%]
小鼠瞬时受体电位香草素（TRPV）通道的特性及其与昆虫化合物的相互作用
Samantha Griffin,Amanda Garbers,Lauren Banina et al.
Samantha Griffin et al.
A number of insecticidal compounds have been found to affect the insect transient receptor potential vanilloid (TRPV) channel. As this receptor is also found in nematodes, we investigated whether these compounds could also interact with the...
Molecular hybridization of indoles and vanillins via α-hydroxyketone linking for discovering new inhibitor of PVY intercellular traffic [0.03%]
通过α-羟基酮连接茚三酮和香兰素类化合物以发现新的PVY胞间运动抑制剂分子杂化体的研究
Feifei Chen,Jiao Li,Fenyan Wang et al.
Feifei Chen et al.
Potato virus Y (PVY) significantly reduces yield in economically important Solanaceae crops, while the limited availability of effective antiviral agents in the market highlights the necessity for exploring innovative antiviral lead structu...
A symbiotic bacterium regulates the detoxification metabolism of deltamethrin in Aedes albopictus [0.03%]
伊蚊的共生菌对高效氯氟氰菊酯解毒代谢的调控作用
Si-Jia Deng,Lei Tu,Lin Li et al.
Si-Jia Deng et al.
The mosquito Aedes albopictus is an important vector of dengue, chikungunya, and Zika; and is a globally distributed invasive mosquito with increasing resistance to insecticides, thereby posing a serious risk to global public health. Symbio...
Antifungal activity and potential inhibition mechanism of 4-(diethylamino)salicylaldehyde against Rhizoctonia solani [0.03%]
4-（二乙氨基）水杨醛的抑菌活性及其潜在抑制机制研究——以立枯丝核菌为对象
Sishi Huang,Xiaoyue Yang,Jing Zhao et al.
Sishi Huang et al.
Rhizoctonia solani is a significant soil-borne pathogenic fungus that poses a significant threat to the economically important agricultural crops. 4-(Diethylamino)salicylaldehyde (DSA) is a secondary metabolite produced by Streptomyces sp. ...
Polysaccharide from discarded tobacco leaves and its anti-TMV activities [0.03%]
烟草废弃物中多糖的提取及其抗TMV活性研究
Yan Wang,Zhengxuan Wang,Yaping Liu et al.
Yan Wang et al.
Natural polysaccharides have been attracted increasing attention in biopesticides for the antiviral effects. Tobacco leaves enriched the polysaccharides and had the potential against tobacco mosaic virus (TMV), however, the chemical structu...
Antifungal activity and underlying mechanism of action of paeonol against Sclerotium rolfsii [0.03%]
白头翁药用成分芍药醇抗病原真菌根霉作用及机制研究
Chunlan Shi,Hongmei Li,Dewei Yang et al.
Chunlan Shi et al.
Southern blight caused by Sclerotium rolfsii threatens Aconitum carmichaelii cultivation. This study evaluated paeonol's antifungal activity and mechanisms against S. rolfsii. Using carrier toxicity assays, paeonol showed potent inhibition ...
Exposure to trans-anethole impairs reproduction and inhibits glutathione-S-transferase (GST) in engorged Rhipicephalus microplus female ticks (Acari: Ixodidae) [0.03%]
丁香酚通过消耗红耳红圆爪螨（Rhipicephalus microplus）雌性饱血蜱的谷胱甘肽转移酶而导致其繁殖受损及死亡率增加
Aline Chaves Reis,Isaac Filipe Moreira Konig,Stefania Priscilla de Souza et al.
Aline Chaves Reis et al.
Rhipicephalus microplus, the cattle tick, is a species of great importance to veterinary medicine and is responsible for massive economic losses in agriculture. In our study, engorged R. microplus females were exposed to the natural product...