Challenges in insecticide resistance management: Implications of alternating selection in the yellow fever mosquito, Aedes aegypti [0.03%]
杀虫剂抗性治理的挑战——交替选择对黄热病媒介埃及伊蚊的影响
Dylan Brown,Michael Dub,Josh Manganaris et al.
Dylan Brown et al.
Insecticide resistance in Aedes aegypti is driven by multiple mechanisms, yet the dynamics of their development under defined selection regimes remain unclear. Here, we established laboratory selection lines from a field-collected parental ...
Bombyx mori RPS3 participates in the UV damage repair of Bombyx mori nucleopolyhedrovirus by interacting with Bm65 [0.03%]
家蚕RPS3通过与Bm65互作参与家蚕核型多角体病毒紫外线损伤修复
Qi Tang,Jiayin Huang,Qiannan Su et al.
Qi Tang et al.
UV radiation in sunlight easily causes the inactivation of baculovirus biopesticides. However, the DNA repair mechanisms of most baculoviruses after UV radiation remain unclear. Bombyx mori nucleopolyhedrovirus (BmNPV) Bm65 has been proven ...
Novel amide derivatives containing acylthiourea link targeting insect ryanodine receptors: Design, synthesis, insecticidal activity, and mechanism [0.03%]
含有酰基硫脲键的新型酰胺衍生物靶向昆虫Ryanodine受体：设计、合成、杀虫活性及作用机制研究
Weibin Xie,Hongyuan Zhang,Wei Wei et al.
Weibin Xie et al.
Diamide insecticides targeting insect ryanodine receptors (RyRs) have been widely used for pest control, but have faced growing challenges from resistance driven by RyR mutations. To address this issue, 22 novel amide derivatives containing...
Fusion dsRNAs targeting proteasome subunits HvPSMD1 and HvProsα2 induce high mortality across developmental stages of Henosepilachna vigintioctopunctata [0.03%]
针对蛋白酶体亚基HvPSMD1和HvProsα2的融合dsRNA诱导二十八星瓢虫各发育阶段高致死率
Ahmad Ali Anjum,Larib Rana,Jianxing Li et al.
Ahmad Ali Anjum et al.
Henosepilachna vigintioctopunctata is a major defoliating pest of solanaceous crops in Asia, traditionally managed through chemical insecticides. RNA interference (RNAi) represents a promising and environmentally safe alternative for its co...
Pocket-based lead optimization strategy for the design of laccase inhibitors as potential antifungal agents [0.03%]
基于先导化合物的优化策略在漆酶抑制剂和潜在抗真菌剂中的应用
Xiaoming Zhang,Xuebo Zhang,Xingxing Lu et al.
Xiaoming Zhang et al.
Plant pathogenic fungi are becoming increasingly resistant to antifungal agents, necessitating the development of novel fungicides targeting new pathways. 4-chlorocinnamaldehyde thiosemicarbazide (PMDD-5Y) was the first compound reported to...
Inhibitory activity and antifungal mechanism of venturicidin A against Pyricularia oryzae [0.03%]
Venturicidin A对稻瘟病菌的抑制活性及抑菌机理研究
Yinan Wang,Lin Qi,Fei Liu et al.
Yinan Wang et al.
Rice blast, caused by Pyricularia oryzae, is a devastating disease threatening global rice production. Microbial secondary metabolites represent promising alternatives for disease control. Venturicidin A (VentA), isolated from Streptomyces ...
Responses and regulatory mechanisms of soil microbiome and antibiotic resistome to carbendazim and ZnO nanoparticles [0.03%]
苯并咪唑和氧化锌纳米颗粒对土壤微生物组和抗性基因的影响及作用机制研究
Shunli Xiao,Conglai Zheng,Jing Yang et al.
Shunli Xiao et al.
Exogenous pollutants may alter the profile of antibiotic resistance genes (ARGs) in soil. Substantial application of a fungicide carbendazim (CBD) and ZnO nanoparticles (nZnO) in modern agriculture has led to serious combined pollution in s...
FgNR gene regulates growth, pathogenicity, and fungicide sensitivity in Fusarium graminearum [0.03%]
FgNR基因调控镰孢菌的生长、致病性和杀菌剂敏感性
Bingyang Hu,Mingcan Yin,Xuhao Guo et al.
Bingyang Hu et al.
Fusarium graminearum is the predominant pathogenic fungus causing Fusarium head blight, posing significant threats to food security and agricultural development. In this study, gene knockout technology was employed to construct FgNR (nitrat...
Insights on the translocation, metabolism, and subcellular distribution of mandipropamid enantiomers in spinach (Spinacia oleracea L.) and the effect of cultivation condition and heavy metal lead (Pb) [0.03%]
研究自色甘酸对映体在菠菜中次生代谢、亚细胞分布及其在不同栽培条件和重金属铅胁迫下的转运特性得的见解
Aihui Zhang,Wenhao Xiong,Zhiyun Yang et al.
Aihui Zhang et al.
The fate of pesticides within crops is a critical determinant of environmental risk, influenced by various factors such as cultivation conditions and exogenous substances, which necessitate thorough investigation. This study examines the tr...
Multi-omics analyses reveal that DMDS-induced embryonic developmental arrest leads to eggshell damage and secondary suppression of chitin biosynthesis in Meloidogyne incognita [0.03%]
多组学分析揭示DMDS诱导的卵形拟松鼠猴囊肿胚胎发育停滞导致卵壳损伤及二次抑制虫甲壳质生物合成
Jingyi Liu,Xin Wang,Xiaoyue Sun et al.
Jingyi Liu et al.
Root-knot nematode (RKN) eggs have a multilayered structure that allows them to survive long-term in soil, serving as a major source of reinfestation. Dimethyl disulfide (DMDS), an efficient and environmentally friendly fumigant alternative...