Avermectin disrupts blood-brain barrier integrity in zebrafish larvae via the Wnt/β-catenin signaling pathway [0.03%]
avermectin通过Wnt/β-catenin信号通路破坏斑马鱼幼虫血脑屏障完整性
Wei-Guo Wang,Lin-Jing Du,Huan-Ou Ma et al.
Wei-Guo Wang et al.
Avermectin, a widely used insecticide, has raised widespread concern over its potential toxic risk to non-target organisms. The safety of the nervous system occupies a crucial position in pesticide risk assessment, primarily because it is h...
Functional and genetic validation for indazapyroxamet as an antagonist of insect TRPV channels [0.03%]
用于验证indazapyroxamet作为昆虫TRPV通道拮抗剂的功能和遗传学证
Tianhao Zhou,Zihan Cheng,Yanbing Zhu et al.
Tianhao Zhou et al.
Transient receptor potential vanilloid (TRPV) channels formed by Nanchung (Nan) and Inactive (Iav) subunits are essential for mechanosensation and coordinated locomotion in insects and represent validated targets of several commercial insec...
A novel endophytic Penicillium sp. JL76001 and its metabolite sclerotiorin: A multi-target and sustainable strategy for biocontrol of tomato Fusarium wilt [0.03%]
一株新型内生曲霉JL76001及其代谢产物菌核菌素：一种多靶标和可持续防控番茄枯萎病的策略
Xuecheng Sun,Yutong Feng,Pan Xiang et al.
Xuecheng Sun et al.
Tomato Fusarium wilt, caused by Fusarium oxysporum f. sp. lycopersici (FOL), is a devastating disease that leads to yield losses of up to 67% in severely affected regions. Current control strategies, such as chemical treatments and resistan...
Transcriptomic and physiological evidence for magnolol antifungal activity against fusarium oxysporum f. sp. cubense tropical race 4 [0.03%]
小檗酚抗枯萎病菌的转录组和生理学证据
Wei Zhang,Yushan Liu,Mudassar Ahmad et al.
Wei Zhang et al.
Banana Fusarium wilt, caused by Fusarium oxysporum f. sp. cubense Tropical Race 4 (Foc TR4), ranks among the most devastating soil-borne fungal diseases. Prolonged use of single-target fungicides can lead to environmental contamination, res...
RNA interference targeting BxNDUFA2 impairs mitochondrial function and triggers oxidative stress to control pine wood nematode (Bursaphelenchus xylophilus) [0.03%]
RNA干扰靶向BxNDUFA2可抑制松材线虫线粒体功能及诱导其氧化应激反应以控制线虫危害
Yuda Xu,Xianzhen Zhou,Xianghua Liu et al.
Yuda Xu et al.
Pine wilt disease (PWD), caused by the pine wood nematode (Bursaphelenchus xylophilus, PWN), is a devastating forest disease with limited eco-friendly control strategies, making novel species-specific control methods an urgent research prio...
Synthesis, characterization, and antimicrobial properties of 8-Hydroxyquinoline-based group 4 metal complexes for plant pathogen control [0.03%]
一类基于8-羟基喹啉的第四族金属配合物的合成、表征及抗菌性质研究
Tiankun Zhao,Baoqing Lv,Yinan Ding et al.
Tiankun Zhao et al.
Rice bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is a destructive disease that seriously threatens rice production. Developing effective, low-dose, and low-risk bactericides is therefore important for sustain...
Dietary manganese potentiates BmNPV resistance in silkworms via BmcGLR-mediated activation of BmRelish through BmSTING [0.03%]
锰通过BmcGLR介导的BmSTING-BmRelish信号激活提高家蚕对 Bombyx mori 核型多角体病毒的抗性
Haonan Meng,Xiaochun Jiang,Minhui Yu et al.
Haonan Meng et al.
The silkworm (Bombyx mori) is a vital economic species threatened by Bombyx mori nucleopolyhedrovirus (BmNPV), causing severe losses in sericulture. Here, we demonstrate that dietary Mn2+ supplementation enhances silkworm resistance to BmNP...
Synergistic toxicity of abamectin with nanoplastics in rainbow trout mediated by gut-liver axis disruption: Insights into oxidative stress, metabolic dysregulation, and microbiota change [0.03%]
阿维菌素与纳米塑料协同毒性引起虹鳟鱼肠肝轴紊乱：氧化应激、代谢失调及微生物群变化的启示
Yongxin Shang,Shanshan Zhao,Zhenlu Wang et al.
Yongxin Shang et al.
Abamectin (ABM), a widely used pesticide in aquaculture, may interact with pervasive environmental contaminants like nanoplastics (NPs), potentially altering its toxicity to non-target organisms. This study investigated the synergistic effe...
Post-transcriptional regulation of ABCB1 by miR-34-5p is associated with emamectin benzoate susceptibility in Spodoptera frugiperda [0.03%]
miR-34-5p作用于ABCB1的表观遗传调控与甜菜夜蛾阿维菌素苯甲酸盐敏感性相关性分析
Congsai Wang,Jingdong Li,Zikun Wang et al.
Congsai Wang et al.
Emamectin benzoate serves as a critical insecticide for controlling Spodoptera frugiperda. However, the emergence of resistance to emamectin benzoate poses a significant challenge to effective pest management, and the underlying genetic mec...
Antifungal products and associated mechanisms of action in the fight against Didymella segeticola responsible for tea and tobacco leaf spot diseases [0.03%]
防治茶烟饼病菌（Didymella segeticola）的抗真菌产品及其作用机制
Christian Bailly
Christian Bailly
The fungus Didymella segeticola is a major plant pathogen which causes significant damages to cultures and important economic losses. It is chiefly responsible for leaf spots and leaf blights of tea and tobacco species, and at least seven o...