Copper exposure elicits pyroptosis and inflammation in bursa of Fabricius and omega-3 reverses this phenomenon by inhibiting NF-κB-NLRP3-GSDMD axis: In vivo, in vitro, and in silico investigations [0.03%]
铜暴露引发法氏囊中炎性焦亡和炎症反应，而ω-3可抑制NF-κB-NLRP3-GSDMD轴逆转上述现象：体内实验、体外实验及分子对接研究
Yufei Cao,Weiyin Zhang,Boran Zhou et al.
Yufei Cao et al.
The overuse of copper (Cu) in feed additives has become a major issue, disrupting animal and ecosystem balance and impairing animal immunity. Omega-3 (ω-3) PUFAs, with immunomodulatory effects, may counteract the immunotoxicity. This study...
Characterization of N-arylamide insecticides to control populations of the green peach aphid, Myzus persicae [0.03%]
N-芳基酰胺类杀虫剂控制桃蚜种群的特性研究
Flinn M O&#x;Hara,Sarah E Mccomic,Zhijun Liu et al.
Flinn M O&#x;Hara et al.
We tested the toxicological profile and influence to feeding behaviors of novel N-arylamide compounds to the green peach aphid, Myzus persicae. Compounds 1 (C9H3Cl2F7N2O) and 2 (C10H3Cl2F8NO) are highly toxic with 4-h LC50 values of 44 ng/m...
Dissipation of penthiopyrad in polyethylene microplastics coexisting soils: Roles of soil properties and microbial communities [0.03%]
五氯硫草灵在土壤中聚乙烯微塑料的消散：土壤性质和微生物群落的作用
Miqi Li,Hui Liu,Kexin Zhang et al.
Miqi Li et al.
Co-existence of fungicides and microplastics in soil may exacerbate the environmental pollution. This study investigated the effects of polyethylene microplastics on the fate of penthiopyrad and soil health. The results showed that the diss...
Effects of afidopyropen treatment and retention on cotton damage caused by Aphis gossypii (Hemiptera: Aphididae) [0.03%]
Afidopyropen对棉蚜(Aphiscottumpiperata(Hemiptera:Aphididae))为害的防治效果及持效性研究
Hui Zha,Xingchen Ren,Ya An et al.
Hui Zha et al.
Cotton aphid (Aphis gossypii Glover) is a harmful pest that affects cotton crops in Xinjiang, China. Afidopyropen is a new type of insecticide that exerts a strong control effect on piercing-sucking pests. In this work, High-performance liq...
Transepithelial transport and mechanism of pyrethroids across Caco-2 cells mediated by transporters [0.03%]
转运蛋白介导的除虫菊酯类化合物跨CaCo-2细胞上皮转运及机制研究
Yuying Liu,Sai Zhang,Tingting Li et al.
Yuying Liu et al.
Oral ingestion is the primary route of human exposure to pesticide residues in agricultural products, with intestinal absorption playing a pivotal role in determining their bioavailability. This study investigated the transepithelial transp...
CRISPR/Cas9 knock-out of nAChR α6 confers resistance to spinosyns in Frankliniella occidentalis and is associated with a higher fitness cost than target-site mutation G275E [0.03%]
弗兰克利马尔斯西ensis西部种中nAChRα6的CRISPR/Cas9敲除可使其对甲氧基丁烯酸盐类化合物产生抗性且比靶点突变G275E适应性更低
A Mocchetti,A A Nikoloudi,J Vontas et al.
A Mocchetti et al.
Thrips are major agricultural pests globally and spinosyn insecticides like spinosad and spinetoram are commonly used for their control. However, numerous cases of resistance have emerged, often linked to mutations in the nicotinic acetylch...
7-Hydroxylathyrol defeats geminivirus through targeting C4 and activating host defense [0.03%]
7-羟基拉他育通过靶向C4并激活宿主防御来对抗植物病毒属病毒
Bi Wang,Xiaoxiao Xu,Wenhao Liang et al.
Bi Wang et al.
Tomato yellow leaf curl virus (TYLCV), which belongs to Geminiviruses, is a notorious plant virus that poses a threat to global agriculture. 7-Hydroxylathyrol is a renowned lathyrane diterpenoid with a broad spectrum of pharmacological acti...
Hydrophilic and lipophilic diblock polymer-based nanoplatform improves the bioactivity of insect growth regulator via inhibiting chitin synthesis [0.03%]
亲疏水两嵌段聚合物纳米平台通过抑制几丁质合成提高昆虫生长调节剂的生物活性
Jie Fan,Shangyuan Wu,Jie Zhang et al.
Jie Fan et al.
Insect growth regulators (IGRs) have shown great potential in green pest management, but their low control efficacy and delayed action limit their widespread application. In recent years, various nanodelivery systems have revolutionized pes...
Nanoscale carbon quantum dots activate antiviral immune responses and modulate the heterogeneous nuclear ribonucleoprotein interface by inducing differential alternative splicing [0.03%]
纳米碳量子点激活抗病毒免疫反应并通过诱导不同的可变剪接来调节异质核核糖核蛋白界面
Tahir Farooq,Muhammad Dilshad Hussain,Dandan Liu et al.
Tahir Farooq et al.
Plant viruses threaten global food security by subverting host defenses, necessitating sustainable solutions. Carbon quantum dots (CQDs)-nanoscale materials with tunable optoelectronic properties and biocompatibility, offer promise in antiv...
Functional and structural insights into P450-mediated resistance: The role of Cyp6g1 and Cyp6g2 in the metabolism of neonicotinoids in Drosophila melanogaster [0.03%]
P450介导的抗性的功能和结构见解：Cyp6g1和Cyp6g2在果蝇Drosophila melanogaster中对新烟碱类物质的代谢中的作用
Alex Giang,Felipe Martelli,Roberto Fusetto et al.
Alex Giang et al.
Insecticide-driven selection pressures have accelerated the evolution and widespread emergence of resistance in insect populations. A major mechanism underlying this resistance is the enhanced metabolic detoxification of insecticides, often...