Utilization of a tetracycline-inducible system for high-level expression of recombinant proteins in Francisella tularensis LVS [0.03%]
四环素诱导系统在LVS中的应用及重组蛋白的高效表达
Valeria Sheshko,Marek Link,Igor Golovliov et al.
Valeria Sheshko et al.
Francisella tularensis is a Gram-negative intracellular pathogen causing tularemia. A number of its potential virulence factors have been identified, but their biology and functions are not precisely known. Understanding the biological and ...
Genomic islands related to Salmonella genomic island 1; integrative mobilisable elements in trmE mobilised in trans by A/C plasmids [0.03%]
与沙门氏菌基因组岛1相关的基因组岛屿；由A/C质粒通过trmE基因座转座的整合可移动元件
Claire de Curraize,Eliane Siebor,Catherine Neuwirth
Claire de Curraize
Salmonella genomic island 1 (SGI1), an integrative mobilisable element (IME), was first reported 20 years ago, in the multidrug resistant Salmonella Typhimurium DT104 clone. Since this first report, many variants and relatives have been fou...
Identification and characterization of a spreadable IncI1 plasmid harbouring a blaCTX-M-15 gene in an Italian human isolate of Salmonella serovar Napoli [0.03%]
意大利沙门氏菌奈亚比型菌株中携带blaCTX-M-15基因的可移动IncI1质粒的鉴定和表征
Sara Petrin,Massimiliano Orsini,Eleonora Mastrorilli et al.
Sara Petrin et al.
Salmonella enterica subsp. enterica serovar Napoli (S. Napoli) ranks among the top serovars causing human infections in Italy, although not common in other European countries. Isolates are generally pan-susceptible or resistant to aminoglyc...
Reciprocal relation between reporter gene transcription and translation efficiency in fission yeast [0.03%]
裂殖酵母报道基因转录与翻译效率间的互惠关系研究
Suchita Srivastava,Satinderdeep Kaur,Hemant K Verma et al.
Suchita Srivastava et al.
The fission yeast, Schizosaccharomyces pombe, is an excellent model for basic research but is not useful for commercial scale protein expression due to lack of strong expression vectors. Earlier, we showed that the lsd90 promoter elicited s...
Novel class 1 integron harboring antibiotic resistance genes in wastewater-derived bacteria as revealed by functional metagenomics [0.03%]
基于功能元基因组学的废水菌群中新型I类整合子及耐药基因的研究
Bridget B McGivern,Rylie K McDonell,Sydney K Morris et al.
Bridget B McGivern et al.
Combatting antibiotic resistance is critical to our ability to treat infectious diseases. Here, we identified and characterized diverse antimicrobial resistance genes, including potentially mobile elements, from synthetic wastewater treatme...
Insights into the individual evolutionary origins of Yersinia virulence factor effector proteins [0.03%]
耶氏菌效应蛋白毒力因子的个体进化起源研究新见解
Veronica R Moorman,James I Cohen
Veronica R Moorman
Pathogenic Yersinia bacteria, including Y. pseudotubuclosis Y. enterocolitica, and Y. pestis, contain the mosaic plasmid pYV that encodes for, among other things, a number of proteinaceous virulence factors. While the evolutionary histories...
An X1α plasmid from a Salmonella enterica serovar Ohio isolate carrying a novel IS26-bounded tet(C) pseudo-compound transposon [0.03%]
来自伤寒沙门菌俄亥俄血清型分离株的含有新的IS26边界tet(C)假复合转座子的X1α质粒
Carol H Pong,Ruth M Hall
Carol H Pong
The sequence of a conjugative plasmid, pSRC22-2, found in a multiply antibiotic resistant Salmonella enterica serovar Ohio isolate SRC22 originally cultured from swine in 1999, was determined. Plasmid pSRC22-2 has a copy number of approxima...
Transcriptomic analysis of Entamoeba histolytica reveals domain-specific sense strand expression of LINE-encoded ORFs with massive antisense expression of RT domain [0.03%]
衣氏肺孢子虫转录组分析揭示LINE-编码ORF的有义链表达具有领域特异性，而逆转录酶结构域则大量表达反义链
Devinder Kaur,Mridula Agrahari,Shashi Shekhar Singh et al.
Devinder Kaur et al.
LINEs are retrotransposable elements found in diverse organisms. Their activity is kept in check by several mechanisms, including transcriptional silencing. Here we have analyzed the transcription status of LINE1 copies in the early-branchi...
Functional analysis of the catalytic triad of the hAT-family transposase TcBuster [0.03%]
hAT家族转位酶TcBuster催化三联体的功能分析
Lauren E Woodard,Felisha M Williams,Isria C Jarrett et al.
Lauren E Woodard et al.
TcBuster is a hAT-family DNA transposon from the red flour beetle, Tribolium castaneum. The TcBuster transposase is of interest for genome engineering as it is highly active in insect and mammalian cells. To test the predicted catalytic tri...
Plasmid localization of sole rrn operon in genomes of Oecophyllibacter saccharovorans (Acetobacteraceae) [0.03%]
Oecophylla bacterium 基因组中唯一的rrn操纵子定位于质粒上
Kah-Ooi Chua,Wah-Seng See-Too,Hoi-Sen Yong et al.
Kah-Ooi Chua et al.
The bacterium Oecophyllibacter saccharovorans of family Acetobacteraceae is a symbiont of weaver ant Oecophylla smaragdina. In our previous study, we published the finding of novel O. saccharovorans strains Ha5T, Ta1 and Jb2 (Chua et al. 20...