In-silico functional analysis of hypothetical proteins from Lactiplantibacillus plantarum plasmids reveals enrichment of cell envelope proteins [0.03%]
乳植菌植生亚种质粒上假想蛋白质的计算机功能分析显示细胞包膜蛋白富集
Dimple Davray,Ram Kulkarni
Dimple Davray
Lactiplantibacillus plantarum is one of the important species of lactic acid bacterium (LAB) found in diverse environments, with many strains exhibiting probiotic properties. In our previous study, 41.6% of protein families (PFs) encoded by...
CFTR and dystrophin encoding plasmids carrying both luciferase reporter gene, nuclear import specific sequences and triple helix sites [0.03%]
包含荧光素酶报告基因、核输入特异性序列和三链结构结合位点的编码囊性纤维化跨膜传导调节器(CFTR)和肌营养不良蛋白的质粒
Delphine Maze,Caroline Girardin,Nathalie Benz et al.
Delphine Maze et al.
Duchenne Muscular Dystrophy and Cystic Fibrosis are two major monogenetic diseases which could be treated by non-viral gene therapy. For this purpose, plasmid DNA (pDNA) coding for the functional genes requires its equipment with signal mol...
Olivia Kosterlitz,Jana S Huisman
Olivia Kosterlitz
Conjugation is a central characteristic of plasmid biology and an important mechanism of horizontal gene transfer in bacteria. However, there is little consensus on how to accurately estimate and report plasmid conjugation rates, in part du...
Plasmid classifications [0.03%]
质粒分类学
M Pilar Garcillán-Barcia,Santiago Redondo-Salvo,Fernando de la Cruz
M Pilar Garcillán-Barcia
Plasmids are universally present in bacteria and play key roles in the dissemination of genes such as antibiotic resistance determinants. Major concepts in Plasmid Biology derive from the efforts to classify plasmids. Here, we review the ma...
Calcium-responsive plasmid copy number regulation is dependent on discrete YopD domains in Yersinia pseudotuberculosis [0.03%]
耶尔森菌属伪结核耶尔森菌中的YopD的几个独立区域调控钙依赖性的质粒拷贝数变化
Pit Engling,Tifaine Héchard,Tomas Edgren et al.
Pit Engling et al.
Yersinia pathogenicity depends mainly on a Type III Secretion System (T3SS) responsible for translocating effector proteins into the eukaryotic target cell cytosol. The T3SS is encoded on a 70 kb, low copy number virulence plasmid, pYV. A k...
Polluted wetlands contain multidrug-resistance plasmids encoding CTX-M-type extended-spectrum β-lactamases [0.03%]
污染湿地中含有编码CTX-M型广谱β-内酰胺酶的耐多药质粒
Ryan T Botts,Dawne M Page,Joseph A Bravo et al.
Ryan T Botts et al.
While most detailed analyses of antibiotic resistance plasmids focus on those found in clinical isolates, less is known about the vast environmental reservoir of mobile genetic elements and the resistance and virulence factors they encode. ...
Reprogramming Targeted-Antibacterial-Plasmids (TAPs) to achieve broad-host range antibacterial activity [0.03%]
重新编程特异性靶向抗菌质粒(TAP)，以实现广谱抗菌活性
Sarah Djermoun,Audrey Reuter,Elisabeth Derollez et al.
Sarah Djermoun et al.
The emergence and spread of antimicrobial resistance results in antibiotic inefficiency against multidrug resistant bacterial strains. Alternative treatment to antibiotics must be investigated to fight bacterial infections and limit this gl...
Anand P Maurya,Alessandro Lazdins,Helen Wilson et al.
Anand P Maurya et al.
Replication control of many plasmids is mediated by the balance between the positive and negative effects of Rep protein binding repeated sequences (iterons) associated with the replication origin, oriV. Negative control is thought to be me...
SSR identification and phylogenetic analysis in four plant species based on complete chloroplast genome sequences [0.03%]
基于完整叶绿体基因组序列的四种植物中SSR标记的鉴定和亲缘分析
Yueyi Zhu,Xianwen Zhang,Shufeng Yan et al.
Yueyi Zhu et al.
The effective utilization of traditional Chinese medicine (TCM) has been challenged by the difficulty to accurately distinguish between similar plant varieties. The stability and conservation of the chloroplast genome can aid in resolving g...
Carriage of three plasmids in a single human clinical isolate of Clostridioides difficile [0.03%]
单个人临床分离艰难梭菌中三种质粒的携带情况
Anna M Roseboom,Quinten R Ducarmon,Bastian V H Hornung et al.
Anna M Roseboom et al.
A subset of clinical isolates of Clostridioides difficile contains one or more plasmids and these plasmids can harbor virulence and antimicrobial resistance determinants. Despite their potential importance, C. difficile plasmids remain poor...